| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0986708 |
| H3-3B | H3.3 histone B | 0.0493253 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.048559 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0483386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0469368 |
| KLF10 | Kruppel-like factor 10 | 0.0460986 |
| SQSTM1 | sequestosome 1 | 0.0384639 |
| JUN | jun proto-oncogene | 0.0357484 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0353126 |
| TXNIP | thioredoxin interacting protein | 0.0339887 |
| IRF1 | interferon regulatory factor 1 | 0.0323892 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0309429 |
| TMSB10 | thymosin beta 10 | 0.0305726 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0300486 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0296457 |
| HDAC9 | histone deacetylase 9 | 0.0266775 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.026286 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0261207 |
| RPL23 | ribosomal protein L23 | 0.0251789 |
| HMGB2 | high mobility group box 2 | 0.0251009 |
| SERTAD2 | SERTA domain containing 2 | 0.0244035 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0239497 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0238261 |
| LMNA | lamin A/C | 0.0238203 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0235976 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0232278 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0225485 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0222357 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0218439 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0216376 |
| SDC4 | syndecan 4 | 0.0213705 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0210415 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0206122 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0204108 |
| AHNAK | AHNAK nucleoprotein | 0.0196084 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0190213 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0186732 |
| MT1X | metallothionein 1X | 0.0179385 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.017704 |
| AHR | aryl hydrocarbon receptor | 0.0176471 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0174577 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0174303 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0174169 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0169265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0168362 |
| RPS24 | ribosomal protein S24 | 0.0168353 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0168056 |
| RPL37A | ribosomal protein L37a | 0.0166871 |
| JMJD1C | jumonji domain containing 1C | 0.0165062 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0164695 |
| INSIG1 | insulin induced gene 1 | 0.016381 |
| B2M | beta-2-microglobulin | 0.0162452 |
| ZFP36 | ZFP36 ring finger protein | 0.0159419 |
| CADM1 | cell adhesion molecule 1 | 0.015871 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0158572 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0157993 |
| MED13 | mediator complex subunit 13 | 0.0157809 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0155913 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0154448 |
| RPL5 | ribosomal protein L5 | 0.0153672 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0153057 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0152911 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0152487 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0152177 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.015161 |
| UPP1 | uridine phosphorylase 1 | 0.0151138 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0147679 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0147149 |
| PKM | pyruvate kinase, muscle | 0.014659 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0145821 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.014458 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0143644 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0142987 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0142728 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0141415 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0140465 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.014017 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0140047 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0139883 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0138542 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0138472 |
| ADM | adrenomedullin | 0.013735 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0136765 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0136715 |
| AUTS2 | autism susceptibility candidate 2 | 0.0136607 |
| MT1E | metallothionein 1E | 0.013622 |
| S100A9 | S100 calcium binding protein A9 | 0.0135864 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0135263 |
| RACK1 | receptor for activated C kinase 1 | 0.0135222 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0134321 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0133576 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0133307 |
| PLEC | plectin | 0.0133036 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0132147 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0131586 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0131391 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0131291 |
| RPL7 | ribosomal protein L7 | 0.0130686 |
| ACTN4 | actinin, alpha 4 | 0.0129401 |
| TNPO1 | transportin 1 | 0.0129251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.286512 |
| COL6A3 | collagen, type VI, alpha 3 | -0.138071 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0889596 |
| FN1 | fibronectin 1 | -0.0865914 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0694322 |
| COL5A1 | collagen, type V, alpha 1 | -0.0601861 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.057162 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0538425 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0537262 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0516855 |
| CALU | calumenin | -0.050923 |
| CDH13 | cadherin 13 | -0.050326 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0485272 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0465629 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0427689 |
| IL6 | interleukin 6 | -0.0421791 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0411575 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0389883 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0388702 |
| NDRG1 | N-myc downstream regulated 1 | -0.0387697 |
| LOX | lysyl oxidase | -0.0386133 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0382655 |
| POTEF | POTE ankyrin domain family, member F | -0.036532 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0363314 |
| GLIS3 | GLIS family zinc finger 3 | -0.0363119 |
| CALD1 | caldesmon 1 | -0.0354362 |
| VIM | vimentin | -0.0352757 |
| LMAN1 | lectin, mannose-binding, 1 | -0.03508 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0347928 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0346489 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0344649 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0341475 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0340551 |
| COL1A2 | collagen, type I, alpha 2 | -0.0337628 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0333615 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0333151 |
| MAP1B | microtubule-associated protein 1B | -0.0323378 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0301974 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0298363 |
| HLA-B | major histocompatibility complex, class I, B | -0.0297405 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0292192 |
| RAI14 | retinoic acid induced 14 | -0.0287012 |
| COPA | coatomer protein complex, subunit alpha | -0.0277855 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.026837 |
| CDK13 | cyclin-dependent kinase 13 | -0.0264128 |
| TMEM165 | transmembrane protein 165 | -0.026337 |
| SEC24A | SEC24 family member A | -0.0261211 |
| COG5 | component of oligomeric golgi complex 5 | -0.0260069 |
| TNS3 | tensin 3 | -0.0259627 |
| LOXL2 | lysyl oxidase-like 2 | -0.0259533 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0257557 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0256975 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0256311 |
| PRSS23 | protease, serine, 23 | -0.0253244 |
| SEC24D | SEC24 family member D | -0.0246287 |
| TPM1 | tropomyosin 1 (alpha) | -0.0244163 |
| MAP4 | microtubule-associated protein 4 | -0.0243248 |
| VEGFC | vascular endothelial growth factor C | -0.0240032 |
| PGK1 | phosphoglycerate kinase 1 | -0.0239131 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.023502 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0233937 |
| VEGFA | vascular endothelial growth factor A | -0.0224863 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0218851 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0217113 |
| EGFR | epidermal growth factor receptor | -0.0216888 |
| RAB1A | RAB1A, member RAS oncogene family | -0.021683 |
| RNF145 | ring finger protein 145 | -0.0216358 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0214549 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0204986 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0203207 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0198406 |
| RTN4 | reticulon 4 | -0.0197754 |
| SBF2 | SET binding factor 2 | -0.0195865 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0195343 |
| NAV1 | neuron navigator 1 | -0.0195127 |
| MMP12 | matrix metallopeptidase 12 | -0.0195047 |
| SRP54 | signal recognition particle 54kDa | -0.0193746 |
| MYO1E | myosin IE | -0.0190355 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0189406 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0185497 |
| CANX | calnexin | -0.0183846 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.018251 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0182306 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0181555 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0178616 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0175485 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0175029 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0174448 |
| ECE1 | endothelin converting enzyme 1 | -0.0173788 |
| NBAS | neuroblastoma amplified sequence | -0.0173267 |
| HLA-C | major histocompatibility complex, class I, C | -0.0172193 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0172007 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0170945 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0167961 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0166419 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0166413 |
| COL7A1 | collagen, type VII, alpha 1 | -0.016486 |
| RUNX1 | runt-related transcription factor 1 | -0.016362 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0163219 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0163215 |
