| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.149034 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.133929 |
| PTMA | prothymosin, alpha | 0.058699 |
| LDHA | lactate dehydrogenase A | 0.0580602 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0570864 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0533916 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0533257 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0476575 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0471817 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0461481 |
| WAC | WW domain containing adaptor with coiled-coil | 0.046105 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0417581 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0396988 |
| YBX3 | Y box binding protein 3 | 0.0380639 |
| SET | SET nuclear proto-oncogene | 0.037313 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036477 |
| CANX | calnexin | 0.0333423 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.032977 |
| MKI67 | marker of proliferation Ki-67 | 0.0327148 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.031581 |
| ECT2 | epithelial cell transforming 2 | 0.0315514 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0310944 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0302144 |
| ZFR | zinc finger RNA binding protein | 0.0300995 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0289278 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0287924 |
| CD44 | CD44 molecule (Indian blood group) | 0.0275508 |
| CENPF | centromere protein F, 350/400kDa | 0.0275486 |
| UBB | ubiquitin B | 0.0273084 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272993 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0272022 |
| HMGB2 | high mobility group box 2 | 0.0269109 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0266966 |
| FNIP1 | folliculin interacting protein 1 | 0.02642 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0258972 |
| KIF4A | kinesin family member 4A | 0.0257915 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0257184 |
| EGR1 | early growth response 1 | 0.0252658 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0250652 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.024612 |
| HDAC9 | histone deacetylase 9 | 0.024594 |
| HJURP | Holliday junction recognition protein | 0.0244297 |
| KIF5B | kinesin family member 5B | 0.0239834 |
| RIGI | RNA sensor RIG-I | 0.0236954 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0233976 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0227581 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0226843 |
| TPX2 | TPX2, microtubule-associated | 0.0226218 |
| TMSB10 | thymosin beta 10 | 0.0225655 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0224383 |
| PDS5B | PDS5 cohesin associated factor B | 0.0221689 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0218851 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0218356 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0218222 |
| DNER | delta/notch-like EGF repeat containing | 0.0217958 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0215977 |
| PTMS | parathymosin | 0.0213883 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0209492 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0207941 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205475 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0204173 |
| NAV3 | neuron navigator 3 | 0.0203612 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0202737 |
| TMF1 | TATA element modulatory factor 1 | 0.0202074 |
| ANXA2 | annexin A2 | 0.0200784 |
| RBM39 | RNA binding motif protein 39 | 0.0200452 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0200274 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0200262 |
| ZNF638 | zinc finger protein 638 | 0.0200169 |
| ANLN | anillin, actin binding protein | 0.0199722 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0199111 |
| SAFB2 | scaffold attachment factor B2 | 0.0197986 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0197518 |
| ZNF670 | zinc finger protein 670 | 0.0194513 |
| SUGP2 | SURP and G patch domain containing 2 | 0.0192778 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0192269 |
| CEP295 | centrosomal protein 295kDa | 0.0191249 |
| FLNA | filamin A, alpha | 0.0190722 |
| CENPE | centromere protein E, 312kDa | 0.019063 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.018987 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0189834 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0189795 |
| RLF | rearranged L-myc fusion | 0.0188305 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0188032 |
| SEC24A | SEC24 family member A | 0.0187497 |
| ATM | ATM serine/threonine kinase | 0.018688 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0186698 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0186025 |
| PDE8A | phosphodiesterase 8A | 0.0185061 |
| DIAPH3 | diaphanous-related formin 3 | 0.018396 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0183335 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0183102 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0181162 |
| IPO7 | importin 7 | 0.018072 |
| RAI1 | retinoic acid induced 1 | 0.0180604 |
| TBCA | tubulin folding cofactor A | 0.01799 |
| YME1L1 | YME1-like 1 ATPase | 0.0179396 |
| ABI1 | abl-interactor 1 | 0.0178543 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.017834 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0174925 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.288987 |
| MT2A | metallothionein 2A | -0.0594304 |
| ASPH | aspartate beta-hydroxylase | -0.0422578 |
| RPLP1 | ribosomal protein, large, P1 | -0.041821 |
| OSMR | oncostatin M receptor | -0.0382008 |
| VIM | vimentin | -0.0378723 |
| RPL23 | ribosomal protein L23 | -0.0373208 |
| NF1 | neurofibromin 1 | -0.0357553 |
| FTL | ferritin, light polypeptide | -0.0355289 |
| RPLP2 | ribosomal protein, large, P2 | -0.0317873 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0315507 |
| RPL35A | ribosomal protein L35a | -0.0309763 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0297728 |
| SBF2 | SET binding factor 2 | -0.0292777 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0290617 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0285309 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0267004 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0265253 |
| PRELID2 | PRELI domain containing 2 | -0.0256342 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0253589 |
| RPL12 | ribosomal protein L12 | -0.0244836 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0241143 |
| PFN1 | profilin 1 | -0.0240421 |
| IKBIP | IKBKB interacting protein | -0.0235319 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0226807 |
| FN1 | fibronectin 1 | -0.0226143 |
| TXNRD1 | thioredoxin reductase 1 | -0.022598 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0225031 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0224788 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0223795 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0222052 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021844 |
| CFDP1 | craniofacial development protein 1 | -0.0217201 |
| TUT4 | terminal uridylyl transferase 4 | -0.0214976 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0213499 |
| OLA1 | Obg-like ATPase 1 | -0.0212724 |
| ZNF148 | zinc finger protein 148 | -0.0211858 |
| ITGAV | integrin, alpha V | -0.0211093 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.021009 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.020943 |
| NDRG1 | N-myc downstream regulated 1 | -0.0208217 |
| FBXO11 | F-box protein 11 | -0.020768 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0206629 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0206133 |
| PHIP | pleckstrin homology domain interacting protein | -0.020259 |
| ATP11A | ATPase, class VI, type 11A | -0.0202399 |
| CALU | calumenin | -0.0197486 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | -0.0197013 |
| RPS13 | ribosomal protein S13 | -0.0195895 |
| GPHN | gephyrin | -0.0194478 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -0.0193001 |
| TCF12 | transcription factor 12 | -0.0192873 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0190094 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0189768 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0189115 |
| RPL36A | ribosomal protein L36a | -0.0189083 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0188748 |
| GLG1 | golgi glycoprotein 1 | -0.0187304 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0184462 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0184138 |
| AREG | amphiregulin | -0.018361 |
| SRP54 | signal recognition particle 54kDa | -0.0183544 |
| SETD5 | SET domain containing 5 | -0.0183329 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.018319 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0180491 |
| GAN | gigaxonin | -0.0179748 |
| RPS25 | ribosomal protein S25 | -0.0179588 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0179404 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0173756 |
| CEP350 | centrosomal protein 350kDa | -0.0173212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0172921 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0172721 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0171646 |
| ZNF292 | zinc finger protein 292 | -0.0171181 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.017106 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0170796 |
| RASAL2 | RAS protein activator like 2 | -0.017036 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0170337 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0168985 |
| DEK | DEK proto-oncogene | -0.0168623 |
| ATXN2 | ataxin 2 | -0.0168597 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0167931 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0166024 |
| COG5 | component of oligomeric golgi complex 5 | -0.0163756 |
| MAP1B | microtubule-associated protein 1B | -0.0163151 |
| MYO9B | myosin IXB | -0.016192 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0161745 |
| PTK2 | protein tyrosine kinase 2 | -0.0161667 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0161478 |
| GOLGB1 | golgin B1 | -0.0161049 |
| STC1 | stanniocalcin 1 | -0.0160381 |
| NBEA | neurobeachin | -0.016026 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0160204 |
| BLOC1S6 | biogenesis of lysosomal organelles complex-1, subunit 6, pallidin | -0.0158739 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0158074 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.015627 |
| CREB1 | cAMP responsive element binding protein 1 | -0.0156227 |
| RPS16 | ribosomal protein S16 | -0.0156185 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0155083 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0155075 |
