| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.230415 |
| SQSTM1 | sequestosome 1 | 0.134776 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.126135 |
| EGR1 | early growth response 1 | 0.0970033 |
| KLF10 | Kruppel-like factor 10 | 0.0969355 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0915109 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.0794341 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0763238 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0760191 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0755075 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0612237 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0609135 |
| TXNIP | thioredoxin interacting protein | 0.0554479 |
| JUN | jun proto-oncogene | 0.053644 |
| B2M | beta-2-microglobulin | 0.0516289 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0495967 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0494477 |
| PLAU | plasminogen activator, urokinase | 0.0491639 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.047724 |
| MT2A | metallothionein 2A | 0.0465336 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0448403 |
| PTMA | prothymosin, alpha | 0.0447423 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0437 |
| HLA-B | major histocompatibility complex, class I, B | 0.0432404 |
| H1-0 | H1.0 linker histone | 0.0420361 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0419583 |
| ZFP36 | ZFP36 ring finger protein | 0.0416204 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0411137 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0401166 |
| FAT1 | FAT atypical cadherin 1 | 0.0398921 |
| S100A6 | S100 calcium binding protein A6 | 0.0362771 |
| INSIG1 | insulin induced gene 1 | 0.0355415 |
| TMSB10 | thymosin beta 10 | 0.0351836 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0351526 |
| LMNA | lamin A/C | 0.0344614 |
| VIM | vimentin | 0.0336693 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0325028 |
| CD83 | CD83 molecule | 0.0323077 |
| SPAG9 | sperm associated antigen 9 | 0.0310716 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0304452 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0302589 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0300291 |
| AHR | aryl hydrocarbon receptor | 0.0287148 |
| FTL | ferritin, light polypeptide | 0.0286022 |
| IER3 | immediate early response 3 | 0.0278806 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0272971 |
| CENPF | centromere protein F, 350/400kDa | 0.0268936 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0265214 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0261279 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.025642 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.025207 |
| IL6ST | interleukin 6 signal transducer | 0.0249651 |
| FOSL1 | FOS-like antigen 1 | 0.0243302 |
| PER1 | period circadian clock 1 | 0.0241503 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0241157 |
| RPS6 | ribosomal protein S6 | 0.0240026 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0237641 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0225477 |
| PLEC | plectin | 0.0218759 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0215596 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213774 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0209353 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0208588 |
| TMSB4X | thymosin beta 4, X-linked | 0.0207612 |
| H3-3B | H3.3 histone B | 0.0202354 |
| SDC4 | syndecan 4 | 0.0200275 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0199498 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0198577 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0197136 |
| HMGA1 | high mobility group AT-hook 1 | 0.019678 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0196295 |
| HLA-A | major histocompatibility complex, class I, A | 0.0194271 |
| S100A10 | S100 calcium binding protein A10 | 0.0193054 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0192195 |
| MCL1 | myeloid cell leukemia 1 | 0.0190716 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0189646 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.018848 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0188279 |
| ACTG1 | actin gamma 1 | 0.018567 |
| RBM25 | RNA binding motif protein 25 | 0.0185305 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0182986 |
| ATF3 | activating transcription factor 3 | 0.0182299 |
| PKM | pyruvate kinase, muscle | 0.0181879 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0179691 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0177719 |
| RPL26 | ribosomal protein L26 | 0.0177284 |
| RPL37A | ribosomal protein L37a | 0.0176516 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0176001 |
| IER2 | immediate early response 2 | 0.0175853 |
| ANXA5 | annexin A5 | 0.0174859 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0174387 |
| EREG | epiregulin | 0.0168846 |
| CADM1 | cell adhesion molecule 1 | 0.0168553 |
| IRF1 | interferon regulatory factor 1 | 0.0168139 |
| WAC | WW domain containing adaptor with coiled-coil | 0.016715 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0166475 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0163174 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0163081 |
| RPS19 | ribosomal protein S19 | 0.0162665 |
| DENND4A | DENN/MADD domain containing 4A | 0.0161908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.0502155 |
| HMGA2 | high mobility group AT-hook 2 | -0.0465829 |
| EFNA5 | ephrin-A5 | -0.0417868 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0410761 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0275617 |
| NDRG1 | N-myc downstream regulated 1 | -0.0272054 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0261933 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0257912 |
| GLIS3 | GLIS family zinc finger 3 | -0.0254643 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0200734 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.018457 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0184165 |
| CTBP2 | C-terminal binding protein 2 | -0.0184163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0182245 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.017016 |
| INTS6 | integrator complex subunit 6 | -0.0157959 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0156756 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0151612 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0151289 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0145968 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0145784 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0144865 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0142912 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0140383 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0139495 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0137844 |
| CD109 | CD109 molecule | -0.0134613 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0134142 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0133106 |
| PRELID2 | PRELI domain containing 2 | -0.0132201 |
| RAI14 | retinoic acid induced 14 | -0.0130957 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0128126 |
| TMEM165 | transmembrane protein 165 | -0.0127512 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0126732 |
| LOXL2 | lysyl oxidase-like 2 | -0.0125028 |
| GPC6 | glypican 6 | -0.0124964 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0124557 |
| TNS3 | tensin 3 | -0.0123317 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0120183 |
| SMYD3 | SET and MYND domain containing 3 | -0.0119822 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0116227 |
| FAM13A | family with sequence similarity 13, member A | -0.0115539 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0115392 |
| FLNB | filamin B, beta | -0.0114535 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0110291 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0110208 |
| COPA | coatomer protein complex, subunit alpha | -0.010752 |
| RAD51B | RAD51 paralog B | -0.0106992 |
| FN1 | fibronectin 1 | -0.0106916 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0105415 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0104842 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0102316 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0101207 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0100737 |
| VEGFA | vascular endothelial growth factor A | -0.00979811 |
| COG5 | component of oligomeric golgi complex 5 | -0.00960143 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00955565 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.00942853 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00940727 |
| SYT1 | synaptotagmin I | -0.00930612 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00929254 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.00909996 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00904853 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0090072 |
| COG6 | component of oligomeric golgi complex 6 | -0.00892952 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00891779 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00884189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.00858556 |
| NAV1 | neuron navigator 1 | -0.00854442 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00849572 |
| FRY | furry homolog (Drosophila) | -0.00848647 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.00842726 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.00835421 |
| STC2 | stanniocalcin 2 | -0.00817874 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0081331 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00810816 |
| ASPH | aspartate beta-hydroxylase | -0.00805179 |
| EXOC4 | exocyst complex component 4 | -0.00803271 |
| AEBP2 | AE binding protein 2 | -0.00802967 |
| PTK2 | protein tyrosine kinase 2 | -0.00800844 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.00798286 |
| SUCO | SUN domain containing ossification factor | -0.00789702 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.00784948 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00781587 |
| HDLBP | high density lipoprotein binding protein | -0.00765749 |
| PRKCA | protein kinase C, alpha | -0.00760325 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00755696 |
| CDK13 | cyclin-dependent kinase 13 | -0.00741166 |
| RIC1 | RAB6A GEF complex partner 1 | -0.00733593 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.00729787 |
| CALU | calumenin | -0.00726883 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00718695 |
| LRRC23 | leucine rich repeat containing 23 | -0.00716701 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.00701271 |
| NRP1 | neuropilin 1 | -0.00700488 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0069421 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00692378 |
| OXR1 | oxidation resistance 1 | -0.00692268 |
| HELZ | helicase with zinc finger | -0.00684971 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.00680985 |
