Hashimoto Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0677607
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Genes

308 genes associated with the disease Hashimoto Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACP1 acid phosphatase 1, soluble
ADA adenosine deaminase
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AIM2 absent in melanoma 2
AIRE autoimmune regulator
AMH anti-Mullerian hormone
APOA1 apolipoprotein A-I
AQP3 aquaporin 3 (Gill blood group)
AQP4 aquaporin 4
ATN1 atrophin 1
ATXN2 ataxin 2
AVP arginine vasopressin
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BLK BLK proto-oncogene, Src family tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG3 BTG family, member 3
C1S complement component 1, s subcomponent
C3 complement component 3
C6ORF47 chromosome 6 open reading frame 47
CA10 carbonic anhydrase X
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD19 CD19 molecule
CD1A CD1a molecule
CD1C CD1c molecule
CD24 CD24 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD68 CD68 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDX2 caudal type homeobox 2
CEP128 centrosomal protein 128kDa
CHDH choline dehydrogenase
CLCNKB chloride channel, voltage-sensitive Kb
CLDN1 claudin 1
CLDN7 claudin 7
COL1A1 collagen, type I, alpha 1
COX2
CSF1R colony stimulating factor 1 receptor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAP death-associated protein
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DIO2 deiodinase, iodothyronine, type II
DNASE1 deoxyribonuclease I
DOCK11 dedicator of cytokinesis 11
DPP4 dipeptidyl-peptidase 4
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
ECD ecdysoneless homolog (Drosophila)
EDN1 endothelin 1
EDNRA endothelin receptor type A
EOMES eomesodermin
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F11R F11 receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN3 fibrillin 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCRL1 Fc receptor-like 1
FCRL2 Fc receptor-like 2
FCRL3 Fc receptor-like 3
FCRLA Fc receptor-like A
FLNB filamin B, beta
FOXD3 forkhead box D3
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS6 growth arrest-specific 6
GAST gastrin
GATA3 GATA binding protein 3
GEM GTP binding protein overexpressed in skeletal muscle
GHRH growth hormone releasing hormone
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPX3 glutathione peroxidase 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H2AJ histone cluster 1, H2aj
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGH immunoglobulin heavy locus
IKZF2 IKAROS family zinc finger 2 (Helios)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL33R interleukin 33 receptor
IL34 interleukin 34
IL37 interleukin 37
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
INS insulin
IP6K3 inositol hexakisphosphate kinase 3
IRAK2 interleukin-1 receptor-associated kinase 2
IRF8 interferon regulatory factor 8
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG1 jagged 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LPP LIM domain containing preferred translocation partner in lipoma
LTA lymphotoxin alpha
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MBIP MAP3K12 binding inhibitory protein 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCAM1 neural cell adhesion molecule 1
NCOA4 nuclear receptor coactivator 4
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PCNA proliferating cell nuclear antigen
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDLIM7 PDZ and LIM domain 7 (enigma)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAT plasminogen activator, tissue
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLG polymerase (DNA directed), gamma
PPARG peroxisome proliferator-activated receptor gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCE protein kinase C, epsilon
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RAB4A RAB4A, member RAS oncogene family
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
RENBP renin binding protein
RET ret proto-oncogene
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SCARB1 scavenger receptor class B, member 1
SCGB3A2 secretoglobin, family 3A, member 2
SDK2 sidekick cell adhesion molecule 2
SEC23B Sec23 homolog B (S. cerevisiae)
SELENOS selenoprotein S
SEPP1 selenoprotein P, plasma, 1
SETD2 SET domain containing 2
SH2D1A SH2 domain containing 1A
SIRT1 sirtuin 1
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A27 solute carrier family 25, member 27
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SOAT1 sterol O-acyltransferase 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
TAS2R38 taste receptor, type 2, member 38
TBX1 T-box 1
TBX2 T-box 2
TBX21 T-box 21
TERT telomerase reverse transcriptase
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
THRB thyroid hormone receptor, beta
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)
TK1 thymidine kinase 1, soluble
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TPO thyroid peroxidase
TRIM60 tripartite motif containing 60
TSHB thyroid stimulating hormone, beta
TSHR thyroid stimulating hormone receptor
TTC7A tetratricopeptide repeat domain 7A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UNC93B1 unc-93 homolog B1 (C. elegans)
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
WDR11 WD repeat domain 11
ZFAT zinc finger and AT hook domain containing