Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4II-01A-11R-A266-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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364 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4II-01A-11R-A266-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAMP angio-associated, migratory cell protein
AASDH aminoadipate-semialdehyde dehydrogenase
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABT1 activator of basal transcription 1
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACTL6A actin-like 6A
ACTL8 actin-like 8
ADAM20 ADAM metallopeptidase domain 20
ADRBK1 adrenergic, beta, receptor kinase 1
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AGTPBP1 ATP/GTP binding protein 1
AK2 adenylate kinase 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AMD1 adenosylmethionine decarboxylase 1
ANAPC5 anaphase promoting complex subunit 5
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD29 ankyrin repeat domain 29
ANO1 anoctamin 1, calcium activated chloride channel
APLN apelin
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL5A ADP-ribosylation factor-like 5A
ARMC1 armadillo repeat containing 1
ATF6B activating transcription factor 6 beta
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP11B ATPase, class VI, type 11B
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATXN1 ataxin 1
BAG6 BCL2-associated athanogene 6
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL10 B-cell CLL/lymphoma 10
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BSDC1 BSD domain containing 1
BTBD9 BTB (POZ) domain containing 9
C11ORF24 chromosome 11 open reading frame 24
C15ORF54 chromosome 15 open reading frame 54
C16ORF70 chromosome 16 open reading frame 70
C17ORF105 chromosome 17 open reading frame 105
C19ORF26 chromosome 19 open reading frame 26
C1ORF204 chromosome 1 open reading frame 204
C2ORF69 chromosome 2 open reading frame 69
C2ORF76 chromosome 2 open reading frame 76
C4ORF32 chromosome 4 open reading frame 32
C6ORF106 chromosome 6 open reading frame 106
C6ORF15 chromosome 6 open reading frame 15
C6ORF25 chromosome 6 open reading frame 25
C8ORF74 chromosome 8 open reading frame 74
CA5A carbonic anhydrase VA, mitochondrial
CALML5 calmodulin-like 5
CASKIN1 CASK interacting protein 1
CCL11 chemokine (C-C motif) ligand 11
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD2AP CD2-associated protein
CD3EAP CD3e molecule, epsilon associated protein
CEACAM19 carcinoembryonic antigen-related cell adhesion molecule 19
CEP83 centrosomal protein 83kDa
CEP85 centrosomal protein 85kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CHD7 chromodomain helicase DNA binding protein 7
CHKA choline kinase alpha
CKB creatine kinase, brain
CLEC17A C-type lectin domain family 17, member A
CLEC18A C-type lectin domain family 18, member A
CLEC18B C-type lectin domain family 18, member B
CLTC clathrin, heavy chain (Hc)
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNKSR3 CNKSR family member 3
CNOT11 CCR4-NOT transcription complex, subunit 11
COPS5 COP9 signalosome subunit 5
CPT1A carnitine palmitoyltransferase 1A (liver)
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CSPP1 centrosome and spindle pole associated protein 1
CTTN cortactin
CTTNBP2NL CTTNBP2 N-terminal like
CUL1 cullin 1
CXCL5 chemokine (C-X-C motif) ligand 5
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DEFB4A defensin, beta 4A
DEGS2 delta(4)-desaturase, sphingolipid 2
DENR density-regulated protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
EFR3A EFR3 homolog A (S. cerevisiae)
EIF4E eukaryotic translation initiation factor 4E
ELL elongation factor RNA polymerase II
EMC8 ER membrane protein complex subunit 8
ENTHD1 ENTH domain containing 1
EPHA8 EPH receptor A8
ERCC8 excision repair cross-complementation group 8
ESM1 endothelial cell-specific molecule 1
ESRP1 epithelial splicing regulatory protein 1
ESYT3 extended synaptotagmin-like protein 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM131C family with sequence similarity 131, member C
FAM153C family with sequence similarity 153, member C, pseudogene
FAM162A family with sequence similarity 162, member A
FAM170A family with sequence similarity 170, member A
FAM216A family with sequence similarity 216, member A
FAM21A family with sequence similarity 21, member A
FAM43B family with sequence similarity 43, member B
FAM49B family with sequence similarity 49, member B
FAM69A family with sequence similarity 69, member A
FAM74A3 family with sequence similarity 74, member A3
FAM74A4 family with sequence similarity 74, member A4
FAM84B family with sequence similarity 84, member B
FAM8A1 family with sequence similarity 8, member A1
FAM91A1 family with sequence similarity 91, member A1
FARSB phenylalanyl-tRNA synthetase, beta subunit
FBXO33 F-box protein 33
FBXO9 F-box protein 9
FGF22 fibroblast growth factor 22
FXR1 fragile X mental retardation, autosomal homolog 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL galanin/GMAP prepropeptide
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GALR2 galanin receptor 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GATA5 GATA binding protein 5
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLMN glomulin, FKBP associated protein
GLO1 glyoxalase I
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GOLGA7 golgin A7
GPR157 G protein-coupled receptor 157
GPR52 G protein-coupled receptor 52
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HBS1L HBS1-like translational GTPase
HDAC1 histone deacetylase 1
HEATR3 HEAT repeat containing 3
HIST1H1A histone cluster 1, H1a
HIST1H3E histone cluster 1, H3e
HK2 hexokinase 2
HLTF helicase-like transcription factor
HOMER1 homer scaffolding protein 1
HPDL 4-hydroxyphenylpyruvate dioxygenase-like
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HYAL4 hyaluronoglucosaminidase 4
HYPM huntingtin interacting protein M
IGHMBP2 immunoglobulin mu binding protein 2
IL17A interleukin 17A
IL20 interleukin 20
IMPAD1 inositol monophosphatase domain containing 1
INGX inhibitor of growth family, X-linked, pseudogene
ISCA1 iron-sulfur cluster assembly 1
IZUMO1 izumo sperm-egg fusion 1
JMY junction mediating and regulatory protein, p53 cofactor
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCTD5 potassium channel tetramerization domain containing 5
KDM2A lysine (K)-specific demethylase 2A
KDM5B lysine (K)-specific demethylase 5B
KIAA1210 KIAA1210
KIF3A kinesin family member 3A
KRTAP19-1 keratin associated protein 19-1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LARP4B La ribonucleoprotein domain family, member 4B
LEP leptin
LINC00161 long intergenic non-protein coding RNA 161
LINC00238 long intergenic non-protein coding RNA 238
LINC01548 long intergenic non-protein coding RNA 1548
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
LRRC58 leucine rich repeat containing 58
LRRC8B leucine rich repeat containing 8 family, member B
LYPLA1 lysophospholipase I
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MEIOB meiosis specific with OB domains
METAP1 methionyl aminopeptidase 1
METAP2 methionyl aminopeptidase 2
METTL8 methyltransferase like 8
MFN1 mitofusin 1
MFSD8 major facilitator superfamily domain containing 8
MIAT myocardial infarction associated transcript (non-protein coding)
MINA MYC induced nuclear antigen
MOB4 MOB family member 4, phocein
MPV17L MPV17 mitochondrial membrane protein-like
MREG melanoregulin
MRPL15 mitochondrial ribosomal protein L15
MRPL21 mitochondrial ribosomal protein L21
MRPL42 mitochondrial ribosomal protein L42
MRPS10 mitochondrial ribosomal protein S10
MRS2 MRS2 magnesium transporter
MTFR1 mitochondrial fission regulator 1
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
MYO1H myosin IH
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDP Norrie disease (pseudoglioma)
NDRG1 N-myc downstream regulated 1
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEK1 NIMA-related kinase 1
NEU2 sialidase 2 (cytosolic sialidase)
NEUROD4 neuronal differentiation 4
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OASL 2'-5'-oligoadenylate synthetase-like
OPRD1 opioid receptor, delta 1
OR1N2 olfactory receptor, family 1, subfamily N, member 2
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OTUD6B OTU domain containing 6B
PADI6 peptidyl arginine deiminase, type VI
PAQR3 progestin and adipoQ receptor family member III
PC pyruvate carboxylase
PCDHGA11 protocadherin gamma subfamily A, 11
PHF20L1 PHD finger protein 20-like 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNP purine nucleoside phosphorylase
PNPLA1 patatin-like phospholipase domain containing 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POU5F1B POU class 5 homeobox 1B
PPARD peroxisome proliferator-activated receptor delta
PPAT phosphoribosyl pyrophosphate amidotransferase
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP6R3 protein phosphatase 6, regulatory subunit 3
PPT2 palmitoyl-protein thioesterase 2
PRRC2A proline-rich coiled-coil 2A
PRSS37 protease, serine, 37
PRSS53 protease, serine, 53
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTRH2 peptidyl-tRNA hydrolase 2
PUS7 pseudouridylate synthase 7 (putative)
RAET1L retinoic acid early transcript 1L
RB1CC1 RB1-inducible coiled-coil 1
RCE1 Ras converting CAAX endopeptidase 1
RNF139 ring finger protein 139
RNF149 ring finger protein 149
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPE ribulose-5-phosphate-3-epimerase
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL7L1 ribosomal protein L7-like 1
RPP40 ribonuclease P/MRP 40kDa subunit
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPS6KL1 ribosomal protein S6 kinase-like 1
RRP1B ribosomal RNA processing 1B
RUVBL1 RuvB-like AAA ATPase 1
RWDD4 RWD domain containing 4
SCN1A sodium channel, voltage gated, type I alpha subunit
SCP2 sterol carrier protein 2
SEC61G Sec61 gamma subunit
SERBP1 SERPINE1 mRNA binding protein 1
SIKE1 suppressor of IKBKE 1
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC10A7 solute carrier family 10, member 7
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMG8 SMG8 nonsense mediated mRNA decay factor
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNCB synuclein, beta
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA41 small nucleolar RNA, H/ACA box 41
SPATC1L spermatogenesis and centriole associated 1-like
SPRR4 small proline-rich protein 4
SPZ1 spermatogenic leucine zipper 1
SRPK1 SRSF protein kinase 1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STPG2 sperm-tail PG-rich repeat containing 2
STRN3 striatin, calmodulin binding protein 3
STX11 syntaxin 11
STYX serine/threonine/tyrosine interacting protein
SULT4A1 sulfotransferase family 4A, member 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAS2R31 taste receptor, type 2, member 31
TAS2R5 taste receptor, type 2, member 5
TBC1D22B TBC1 domain family, member 22B
TBC1D23 TBC1 domain family, member 23
TBC1D32 TBC1 domain family, member 32
TBPL2 TATA box binding protein like 2
TCEA1 transcription elongation factor A (SII), 1
TGS1 trimethylguanosine synthase 1
TLX1 T-cell leukemia homeobox 1
TMEM192 transmembrane protein 192
TMEM241 transmembrane protein 241
TMEM45A transmembrane protein 45A
TMEM65 transmembrane protein 65
TMEM68 transmembrane protein 68
TMEM70 transmembrane protein 70
TP53TG5 TP53 target 5
TPCN2 two pore segment channel 2
TRIB1 tribbles pseudokinase 1
TRIM65 tripartite motif containing 65
TRIML1 tripartite motif family-like 1
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TTC13 tetratricopeptide repeat domain 13
TTC14 tetratricopeptide repeat domain 14
TTYH2 tweety family member 2
TUBA4B tubulin, alpha 4b
TUBD1 tubulin, delta 1
UBE2K ubiquitin-conjugating enzyme E2K
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE4B ubiquitination factor E4B
UBFD1 ubiquitin family domain containing 1
UBQLN1 ubiquilin 1
ULK1 unc-51 like autophagy activating kinase 1
UNC5CL unc-5 homolog C (C. elegans)-like
UNC93A unc-93 homolog A (C. elegans)
UNK unkempt family zinc finger
USP16 ubiquitin specific peptidase 16
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VEZT vezatin, adherens junctions transmembrane protein
VMP1 vacuole membrane protein 1
VN1R1 vomeronasal 1 receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WBP2 WW domain binding protein 2
WDR59 WD repeat domain 59
WRB tryptophan rich basic protein
XPO5 exportin 5
YPEL2 yippee-like 2 (Drosophila)
ZACN zinc activated ligand-gated ion channel
ZBED9 zinc finger, BED-type containing 9
ZBTB32 zinc finger and BTB domain containing 32
ZC3H12A zinc finger CCCH-type containing 12A
ZFP91 ZFP91 zinc finger protein
ZMYM1 zinc finger, MYM-type 1
ZMYM6 zinc finger, MYM-type 6
ZNF451 zinc finger protein 451
ZNF713 zinc finger protein 713

low expression

Symbol Name
CHMP3 charged multivesicular body protein 3
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
EXOC7 exocyst complex component 7
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
NONO non-POU domain containing, octamer-binding
PCBP2 poly(rC) binding protein 2
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit