Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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235 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACE angiotensin I converting enzyme
ACER3 alkaline ceramidase 3
ACOT1 acyl-CoA thioesterase 1
ACOT2 acyl-CoA thioesterase 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AIM1 absent in melanoma 1
AMBRA1 autophagy/beclin-1 regulator 1
ANKRD13A ankyrin repeat domain 13A
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APLNR apelin receptor
APLP2 amyloid beta (A4) precursor-like protein 2
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP1 Rho GTPase activating protein 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATF7IP activating transcription factor 7 interacting protein
ATG13 autophagy related 13
ATL3 atlastin GTPase 3
AVPR1A arginine vasopressin receptor 1A
BAK1 BCL2-antagonist/killer 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCL6B B-cell CLL/lymphoma 6, member B
BTN3A2 butyrophilin, subfamily 3, member A2
C14ORF169 chromosome 14 open reading frame 169
C15ORF54 chromosome 15 open reading frame 54
C16ORF82 chromosome 16 open reading frame 82
C20ORF202 chromosome 20 open reading frame 202
C2CD4A C2 calcium-dependent domain containing 4A
CARD17 caspase recruitment domain family, member 17
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCBE1 collagen and calcium binding EGF domains 1
CCDC144NL coiled-coil domain containing 144 family, N-terminal like
CCNYL1 cyclin Y-like 1
CEACAM18 carcinoembryonic antigen-related cell adhesion molecule 18
CEP164 centrosomal protein 164kDa
CHEK1 checkpoint kinase 1
CKAP5 cytoskeleton associated protein 5
CLMP CXADR-like membrane protein
CMTR1 cap methyltransferase 1
COG8 component of oligomeric golgi complex 8
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL5A3 collagen, type V, alpha 3
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSO cathepsin O
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DCLRE1B DNA cross-link repair 1B
DEPDC7 DEP domain containing 7
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIRC1 disrupted in renal carcinoma 1
DNAH2 dynein, axonemal, heavy chain 2
DSCAM Down syndrome cell adhesion molecule
EBI3 Epstein-Barr virus induced 3
EGFL6 EGF-like-domain, multiple 6
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERCC1 excision repair cross-complementation group 1
ETV7 ets variant 7
EXOC2 exocyst complex component 2
FAM109A family with sequence similarity 109, member A
FAM111A family with sequence similarity 111, member A
FAM120B family with sequence similarity 120B
FBXO6 F-box protein 6
FBXW12 F-box and WD repeat domain containing 12
FIGLA folliculogenesis specific basic helix-loop-helix
FLT4 fms-related tyrosine kinase 4
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GBP3 guanylate binding protein 3
GJD3 gap junction protein, delta 3, 31.9kDa
GPR4 G protein-coupled receptor 4
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HAPLN1 hyaluronan and proteoglycan link protein 1
HEATR4 HEAT repeat containing 4
HIPK3 homeodomain interacting protein kinase 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPS5 Hermansky-Pudlak syndrome 5
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
ILK integrin-linked kinase
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
INTS4P2 integrator complex subunit 4 pseudogene 2
IPO7 importin 7
ITGA1 integrin, alpha 1
ITPK1 inositol-tetrakisphosphate 1-kinase
ITSN1 intersectin 1 (SH3 domain protein)
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCNK17 potassium channel, two pore domain subfamily K, member 17
KDM1B lysine (K)-specific demethylase 1B
KDR kinase insert domain receptor
KIAA1549L KIAA1549-like
KIAA1551 KIAA1551
KIAA1586 KIAA1586
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KMT2A lysine (K)-specific methyltransferase 2A
LACE1 lactation elevated 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAP3 leucine aminopeptidase 3
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCTL lactase-like
LHX1 LIM homeobox 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LOC284441 actin-related protein 2 pseudogene
LOC440461 Rho GTPase activating protein 27 pseudogene
LOC641367 cyclin Y-like 1 pseudogene
MB21D1 Mab-21 domain containing 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKI67 marker of proliferation Ki-67
MLKL mixed lineage kinase domain-like
MRGPRE MAS-related GPR, member E
MTO1 mitochondrial tRNA translation optimization 1
MYO1B myosin IB
NCAPG non-SMC condensin I complex, subunit G
NCOA3 nuclear receptor coactivator 3
NLRP2 NLR family, pyrin domain containing 2
NR2E1 nuclear receptor subfamily 2, group E, member 1
NTSR1 neurotensin receptor 1 (high affinity)
NUMB numb homolog (Drosophila)
NUP98 nucleoporin 98kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OSBPL5 oxysterol binding protein-like 5
OVCH2 ovochymase 2 (gene/pseudogene)
PAEP progestagen-associated endometrial protein
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCDH12 protocadherin 12
PCNX pecanex homolog (Drosophila)
PCSK7 proprotein convertase subtilisin/kexin type 7
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEK2 pleckstrin 2
PLVAP plasmalemma vesicle associated protein
POM121L1P POM121 transmembrane nucleoporin-like 1, pseudogene
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRF1 perforin 1 (pore forming protein)
PTAFR platelet-activating factor receptor
PTBP1 polypyrimidine tract binding protein 1
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRK protein tyrosine phosphatase, receptor type, K
PTRF polymerase I and transcript release factor
PUS3 pseudouridylate synthase 3
QPRT quinolinate phosphoribosyltransferase
QRICH1 glutamine-rich 1
RAB19 RAB19, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RASIP1 Ras interacting protein 1
RBM15 RNA binding motif protein 15
RBM7 RNA binding motif protein 7
RET ret proto-oncogene
RIMBP3C RIMS binding protein 3C
RNF213 ring finger protein 213
RNF26 ring finger protein 26
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SEC1P secretory blood group 1, pseudogene
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH2B3 SH2B adaptor protein 3
SHISA6 shisa family member 6
SIDT2 SID1 transmembrane family, member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLFN11 schlafen family member 11
SLFN12 schlafen family member 12
SNORA4 small nucleolar RNA, H/ACA box 4
SNX19 sorting nexin 19
SNX3 sorting nexin 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNE2 spectrin repeat containing, nuclear envelope 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBS2 thrombospondin 2
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR3 toll-like receptor 3
TM4SF18 transmembrane 4 L six family member 18
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM135 transmembrane protein 135
TMEM41B transmembrane protein 41B
TNK1 tyrosine kinase, non-receptor, 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM21 tripartite motif containing 21
TRIM26 tripartite motif containing 26
TRIM36 tripartite motif containing 36
TRIM44 tripartite motif containing 44
TRIM56 tripartite motif containing 56
TRIP11 thyroid hormone receptor interactor 11
TSKS testis-specific serine kinase substrate
TUBAL3 tubulin, alpha-like 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP28 ubiquitin specific peptidase 28
USP48 ubiquitin specific peptidase 48
VAX1 ventral anterior homeobox 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WARS tryptophanyl-tRNA synthetase
XDH xanthine dehydrogenase
ZBP1 Z-DNA binding protein 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF143 zinc finger protein 143
ZNF366 zinc finger protein 366
ZNF618 zinc finger protein 618
ZNF702P zinc finger protein 702, pseudogene
ZNF788 zinc finger family member 788
ZNF792 zinc finger protein 792

low expression

Symbol Name
ARMCX5 armadillo repeat containing, X-linked 5
BTBD10 BTB (POZ) domain containing 10
FBXO28 F-box protein 28
GTF2IP1 general transcription factor IIi pseudogene 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
ZFP69 ZFP69 zinc finger protein
ZNF140 zinc finger protein 140
ZNF562 zinc finger protein 562