Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7095-01A-21R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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225 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7095-01A-21R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A1BG-AS1 A1BG antisense RNA 1
AACS acetoacetyl-CoA synthetase
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABI2 abl-interactor 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACO1 aconitase 1, soluble
ADAM9 ADAM metallopeptidase domain 9
ADRBK1 adrenergic, beta, receptor kinase 1
AGPS alkylglycerone phosphate synthase
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALKBH5 AlkB family member 5, RNA demethylase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKDD1A ankyrin repeat and death domain containing 1A
ANKRD13D ankyrin repeat domain 13 family, member D
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AQP10 aquaporin 10
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
BANF2 barrier to autointegration factor 2
BCAP31 B-cell receptor-associated protein 31
BCORL1 BCL6 corepressor-like 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRMS1L breast cancer metastasis-suppressor 1-like
BZW1 basic leucine zipper and W2 domains 1
C1ORF53 chromosome 1 open reading frame 53
C2ORF47 chromosome 2 open reading frame 47
CABP2 calcium binding protein 2
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPG capping protein (actin filament), gelsolin-like
CCDC116 coiled-coil domain containing 116
CCNK cyclin K
CD68 CD68 molecule
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDRT15 CMT1A duplicated region transcript 15
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CIR1 corepressor interacting with RBPJ, 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CORO1B coronin, actin binding protein, 1B
DCTN1 dynactin 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DENR density-regulated protein
DISP2 dispatched homolog 2 (Drosophila)
DNAAF3 dynein, axonemal, assembly factor 3
DNASE1L1 deoxyribonuclease I-like 1
DNM1P46 dynamin 1 pseudogene 46
DNMBP dynamin binding protein
DQX1 DEAQ box RNA-dependent ATPase 1
DSTYK dual serine/threonine and tyrosine protein kinase
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DUSP10 dual specificity phosphatase 10
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EFNB2 ephrin-B2
EHD2 EH-domain containing 2
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EMP3 epithelial membrane protein 3
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
ERLIN2 ER lipid raft associated 2
FAM126B family with sequence similarity 126, member B
FAM189B family with sequence similarity 189, member B
FAM83G family with sequence similarity 83, member G
FGF11 fibroblast growth factor 11
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLRT2 fibronectin leucine rich transmembrane protein 2
GALT galactose-1-phosphate uridylyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GGN gametogenetin
GLDC glycine dehydrogenase (decarboxylating)
GPR132 G protein-coupled receptor 132
GSTP1 glutathione S-transferase pi 1
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HAT1 histone acetyltransferase 1
HEATR3 HEAT repeat containing 3
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IRF2BP2 interferon regulatory factor 2 binding protein 2
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITGB6 integrin, beta 6
KCNK7 potassium channel, two pore domain subfamily K, member 7
KCTD11 potassium channel tetramerization domain containing 11
KDM2A lysine (K)-specific demethylase 2A
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA0391 KIAA0391
KIAA1161 KIAA1161
KIFAP3 kinesin-associated protein 3
LEP leptin
LETM2 leucine zipper-EF-hand containing transmembrane protein 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMTK3 lemur tyrosine kinase 3
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LTB4R2 leukotriene B4 receptor 2
MAPK7 mitogen-activated protein kinase 7
MBOAT7 membrane bound O-acyltransferase domain containing 7
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MOSPD3 motile sperm domain containing 3
MTSS1 metastasis suppressor 1
MTX2 metaxin 2
MYO1B myosin IB
MYO1C myosin IC
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NRIP1 nuclear receptor interacting protein 1
NUBPL nucleotide binding protein-like
NUTM2F NUT family member 2F
OLA1 Obg-like ATPase 1
ORC2 origin recognition complex, subunit 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PC pyruvate carboxylase
PCDHB11 protocadherin beta 11
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA8 protocadherin gamma subfamily A, 8
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFN1 profilin 1
PHF23 PHD finger protein 23
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEK2 pleckstrin 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PLTP phospholipid transfer protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLM polymerase (DNA directed), mu
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRAP1 proline-rich acidic protein 1
PROSC proline synthetase co-transcribed homolog (bacterial)
PSKH1 protein serine kinase H1
PSKH2 protein serine kinase H2
PXN paxillin
RABGAP1L RAB GTPase activating protein 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD21L1 RAD21-like 1 (S. pombe)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RASGEF1A RasGEF domain family, member 1A
RASIP1 Ras interacting protein 1
RCE1 Ras converting CAAX endopeptidase 1
RFPL3 ret finger protein-like 3
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RNF170 ring finger protein 170
RNLS renalase, FAD-dependent amine oxidase
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RTP2 receptor (chemosensory) transporter protein 2
SCRN3 secernin 3
SERINC3 serine incorporator 3
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SGOL2 shugoshin-like 2 (S. pombe)
SHPK sedoheptulokinase
SMG6 SMG6 nonsense mediated mRNA decay factor
SNTA1 syntrophin, alpha 1
SOCS6 suppressor of cytokine signaling 6
SOX15 SRY (sex determining region Y)-box 15
SP3 Sp3 transcription factor
SPATC1L spermatogenesis and centriole associated 1-like
SPATS2L spermatogenesis associated, serine-rich 2-like
SSB Sjogren syndrome antigen B (autoantigen La)
SSH3 slingshot protein phosphatase 3
STK17B serine/threonine kinase 17b
STON2 stonin 2
STRADB STE20-related kinase adaptor beta
SUFU suppressor of fused homolog (Drosophila)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUMO1 small ubiquitin-like modifier 1
SUMO1P3 SUMO1 pseudogene 3 (functional)
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D25 TBC1 domain family, member 25
TBCE tubulin folding cofactor E
TECPR2 tectonin beta-propeller repeat containing 2
TFE3 transcription factor binding to IGHM enhancer 3
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THEM4 thioesterase superfamily member 4
TM2D2 TM2 domain containing 2
TMEM134 transmembrane protein 134
TMEM237 transmembrane protein 237
TMEM249 transmembrane protein 249
TMEM63C transmembrane protein 63C
TMEM65 transmembrane protein 65
TNK1 tyrosine kinase, non-receptor, 1
TRIM28 tripartite motif containing 28
TRIM58 tripartite motif containing 58
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TSKS testis-specific serine kinase substrate
TSPAN5 tetraspanin 5
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2MP1 ubiquitin-conjugating enzyme E2M pseudogene 1
UBQLN2 ubiquilin 2
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
ULK1 unc-51 like autophagy activating kinase 1
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR12 WD repeat domain 12
WISP3 WNT1 inducible signaling pathway protein 3
ZBTB4 zinc finger and BTB domain containing 4
ZNF460 zinc finger protein 460
ZNF480 zinc finger protein 480
ZNF543 zinc finger protein 543
ZNF766 zinc finger protein 766
ZNF805 zinc finger protein 805
ZSCAN22 zinc finger and SCAN domain containing 22

low expression

Symbol Name
ARMCX5 armadillo repeat containing, X-linked 5
CHIC1 cysteine-rich hydrophobic domain 1
RGPD6 RANBP2-like and GRIP domain containing 6
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZNF175 zinc finger protein 175
ZNF20 zinc finger protein 20
ZNF845 zinc finger protein 845