Heart Block Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway. (Human Phenotype Ontology, HP_0012722)
External Link https://www.disgenet.org/browser/0/1/0/C0018794
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Genes

48 genes associated with the disease Heart Block in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
BTNL2 butyrophilin-like 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALCR calcitonin receptor
CALR calreticulin
CAPG capping protein (actin filament), gelsolin-like
CD46 CD46 molecule, complement regulatory protein
CLCA2 chloride channel accessory 2
COX1
COX2
COX3
CXCL10 chemokine (C-X-C motif) ligand 10
DES desmin
EGR2 early growth response 2
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
GAL galanin/GMAP prepropeptide
GLDN gliomedin
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LDB3 LIM domain binding 3
LMNA lamin A/C
MPZ myelin protein zero
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MYBPC3 myosin binding protein C, cardiac
MYOCD myocardin
ND1
NKX2-5 NK2 homeobox 5
PANX1 pannexin 1
PEX7 peroxisomal biogenesis factor 7
PHYH phytanoyl-CoA 2-hydroxylase
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
REG1A regenerating islet-derived 1 alpha
RO60 Ro60, Y RNA binding protein
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
TGFB1 transforming growth factor, beta 1
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TRIM21 tripartite motif containing 21
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTR transthyretin