Heart development Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
Description The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. (Gene Ontology, GO_0007507)
External Link https://www.wikipathways.org/pathways/WP1591.html
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Genes

44 proteins participating in the Heart development pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
BHLHE40 basic helix-loop-helix family, member e40
BMP10 bone morphogenetic protein 10
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ERBB3 erb-b2 receptor tyrosine kinase 3
FGF10 fibroblast growth factor 10
FGF8 fibroblast growth factor 8 (androgen-induced)
FOXA2 forkhead box A2
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXH1 forkhead box H1
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
HAND1 heart and neural crest derivatives expressed 1
HAND2 heart and neural crest derivatives expressed 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IRX4 iroquois homeobox 4
ISL1 ISL LIM homeobox 1
MAPK1 mitogen-activated protein kinase 1
MEF2C myocyte enhancer factor 2C
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX2-5 NK2 homeobox 5
NOTCH1 notch 1
PITX2 paired-like homeodomain 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SHH sonic hedgehog
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SMYD1 SET and MYND domain containing 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
TBX1 T-box 1
TBX2 T-box 2
TBX20 T-box 20
TBX5 T-box 5
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C