Hedgehog 'on' state Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5632684
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Genes

73 proteins participating in the Hedgehog 'on' state pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BOC BOC cell adhesion associated, oncogene regulated
CDC73 cell division cycle 73
CDON cell adhesion associated, oncogene regulated
CSNK1A1 casein kinase 1, alpha 1
CUL3 cullin 3
DHH desert hedgehog
DZIP1 DAZ interacting zinc finger protein 1
EFCAB7 EF-hand calcium binding domain 7
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
GAS1 growth arrest-specific 1
GAS8 growth arrest-specific 8
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPR161 G protein-coupled receptor 161
GRK2 G protein-coupled receptor kinase 2
HHIP hedgehog interacting protein
IHH indian hedgehog
IQCE IQ motif containing E
ITCH itchy E3 ubiquitin protein ligase
KIF3A kinesin family member 3A
KIF7 kinesin family member 7
NUMB numb homolog (Drosophila)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTCH1 patched 1
PTCH2 patched 2
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SEM1 SEM1 26S proteasome subunit
SHH sonic hedgehog
SMO smoothened, frizzled class receptor
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPOP speckle-type POZ protein
SPOPL speckle-type POZ protein-like
SUFU suppressor of fused homolog (Drosophila)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
ULK3 unc-51 like kinase 3