Hematocrit Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value. (Experimental Factor Ontology, EFO_0004348)
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Genes

61 genes associated with the trait Hematocrit in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.49765
PRKCE protein kinase C, epsilon 1.19892
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.1894
HK1 hexokinase 1 1.12979
TMPRSS6 transmembrane protease, serine 6 1.11353
TP53TG1 TP53 target 1 (non-protein coding) 1.06921
FAM155A family with sequence similarity 155, member A 0.981631
TFR2 transferrin receptor 2 0.897125
HFE hemochromatosis 0.836775
RFX8 RFX family member 8, lacking RFX DNA binding domain 0.718407
PALLD palladin, cytoskeletal associated protein 0.710687
IL17A interleukin 17A 0.622149
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 0.622117
MEGF10 multiple EGF-like-domains 10 0.555773
DMD dystrophin 0.522567
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 0.492916
ALX4 ALX homeobox 4 0.469648
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.36354
MACROD2 MACRO domain containing 2 0.343942
PACRG PARK2 co-regulated 0.320752
SNX29 sorting nexin 29 0.304878
SERGEF secretion regulating guanine nucleotide exchange factor 0.261736
EML6 echinoderm microtubule associated protein like 6 0.250017
NRG1 neuregulin 1 0.234685
HPCAL1 hippocalcin-like 1 0.228768
C4ORF22 chromosome 4 open reading frame 22 0.213253
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.208159
DPP6 dipeptidyl-peptidase 6 0.199041
RAG1 recombination activating gene 1 0.187652
PHTF2 putative homeodomain transcription factor 2 0.186734
GRIK4 glutamate receptor, ionotropic, kainate 4 0.185931
PTPRD protein tyrosine phosphatase, receptor type, D 0.172614
SOX5 SRY (sex determining region Y)-box 5 0.171576
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.168983
CELF5 CUGBP, Elav-like family member 5 0.163364
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.158332
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.153593
CWC22 CWC22 spliceosome-associated protein 0.148221
ACOXL acyl-CoA oxidase-like 0.142234
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.141289
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.139428
EXT2 exostosin glycosyltransferase 2 0.136779
GPC6 glypican 6 0.12557
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.124063
CAMKMT calmodulin-lysine N-methyltransferase 0.120745
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.120611
C11ORF74 chromosome 11 open reading frame 74 0.105081
CSMD1 CUB and Sushi multiple domains 1 0.089259
FRAS1 Fraser extracellular matrix complex subunit 1 0.082933
MECOM MDS1 and EVI1 complex locus 0.081417
GALNS galactosamine (N-acetyl)-6-sulfatase 0.080557
MCM10 minichromosome maintenance complex component 10 0.078582
WDR7 WD repeat domain 7 0.077257
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 0.07197
LINC01446 long intergenic non-protein coding RNA 1446 0.069776
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.069008
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 0.067124
CHN2 chimerin 2 0.066982
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.064425
PHACTR2 phosphatase and actin regulator 2 0.064095
ESRRB estrogen-related receptor beta 0.05985