Hemiplegia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

278 genes co-occuring with the disease Hemiplegia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.517
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 3.252
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 2.862
PLAT plasminogen activator, tissue 2.817
SCN1A sodium channel, voltage gated, type I alpha subunit 2.527
PRRT2 proline-rich transmembrane protein 2 2.465
CRP C-reactive protein, pentraxin-related 2.454
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.331
F2 coagulation factor II (thrombin) 2.301
LIPN lipase, family member N 2.29
ALB albumin 2.229
F3 coagulation factor III (thromboplastin, tissue factor) 2.194
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.102
IL6 interleukin 6 2.092
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.991
ACE angiotensin I converting enzyme 1.97
BDNF brain-derived neurotrophic factor 1.938
DNAH8 dynein, axonemal, heavy chain 8 1.925
INS insulin 1.924
PNKD paroxysmal nonkinesigenic dyskinesia 1.923
TBC1D24 TBC1 domain family, member 24 1.921
TNF tumor necrosis factor 1.895
SCN2A sodium channel, voltage gated, type II alpha subunit 1.892
IL1B interleukin 1, beta 1.879
CKM creatine kinase, muscle 1.839
CKB creatine kinase, brain 1.833
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.83
CKMT1B creatine kinase, mitochondrial 1B 1.829
TAC1 tachykinin, precursor 1 1.815
MOG myelin oligodendrocyte glycoprotein 1.812
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 1.805
COL4A1 collagen, type IV, alpha 1 1.803
GFAP glial fibrillary acidic protein 1.801
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.794
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.781
ADCY5 adenylate cyclase 5 1.774
CD4 CD4 molecule 1.758
RHOBTB2 Rho-related BTB domain containing 2 1.756
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.729
MBP myelin basic protein 1.729
FASTKD2 FAST kinase domains 2 1.694
ACE2 angiotensin I converting enzyme 2 1.683
PCSK5 proprotein convertase subtilisin/kexin type 5 1.659
TUBB4A tubulin, beta 4A class IVa 1.642
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.641
PLG plasminogen 1.625
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.625
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.617
IFNG interferon, gamma 1.608
NOTCH3 notch 3 1.605
ENO2 enolase 2 (gamma, neuronal) 1.603
STXBP1 syntaxin binding protein 1 1.602
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.585
REN renin 1.582
NGF nerve growth factor (beta polypeptide) 1.582
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.58
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.571
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.569
IL10 interleukin 10 1.568
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 1.564
SGCE sarcoglycan, epsilon 1.562
MRS2 MRS2 magnesium transporter 1.561
VWF von Willebrand factor 1.558
TIAM2 T-cell lymphoma invasion and metastasis 2 1.547
THAP1 THAP domain containing, apoptosis associated protein 1 1.529
LGI1 leucine-rich, glioma inactivated 1 1.529
CD8A CD8a molecule 1.529
POMC proopiomelanocortin 1.527
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.52
S100B S100 calcium binding protein B 1.519
CARD16 caspase recruitment domain family, member 16 1.518
PNMA2 paraneoplastic Ma antigen 2 1.509
ANO3 anoctamin 3 1.506
PF4 platelet factor 4 1.502
APOH apolipoprotein H (beta-2-glycoprotein I) 1.492
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.491
TOR1A torsin family 1, member A (torsin A) 1.49
IL1A interleukin 1, alpha 1.482
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.479
CIZ1 CDKN1A interacting zinc finger protein 1 1.475
CNTNAP2 contactin associated protein-like 2 1.474
PCDH19 protocadherin 19 1.467
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.453
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.453
PANX1 pannexin 1 1.453
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.446
POLG polymerase (DNA directed), gamma 1.446
CPZ carboxypeptidase Z 1.438
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 1.434
TANGO2 transport and golgi organization 2 homolog (Drosophila) 1.434
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.433
SP9 Sp9 transcription factor 1.425
CLDN5 claudin 5 1.422
PXDNL peroxidasin-like 1.421
CDKL5 cyclin-dependent kinase-like 5 1.42
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.419
PXDN peroxidasin 1.419
CD68 CD68 molecule 1.417
EPO erythropoietin 1.414
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.41
CD34 CD34 molecule 1.407
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 1.405
BCL2 B-cell CLL/lymphoma 2 1.4
RNF213 ring finger protein 213 1.39
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.383
MGMT O-6-methylguanine-DNA methyltransferase 1.382
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.382
KCNK18 potassium channel, two pore domain subfamily K, member 18 1.381
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.381
IGF1 insulin-like growth factor 1 (somatomedin C) 1.374
ACTB actin, beta 1.372
APOE apolipoprotein E 1.368
FXYD1 FXYD domain containing ion transport regulator 1 1.367
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.359
AIF1 allograft inflammatory factor 1 1.358
NPPB natriuretic peptide B 1.352
RAD51 RAD51 recombinase 1.349
MPO myeloperoxidase 1.347
KCNT1 potassium channel, sodium activated subfamily T, member 1 1.345
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 1.344
FGF14 fibroblast growth factor 14 1.343
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.335
EDN1 endothelin 1 1.334
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.328
AP4B1 adaptor-related protein complex 4, beta 1 subunit 1.323
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.317
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.315
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 1.314
MMP9 matrix metallopeptidase 9 1.312
LRP5 low density lipoprotein receptor-related protein 5 1.309
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.306
GCH1 GTP cyclohydrolase 1 1.306
CXCL8 chemokine (C-X-C motif) ligand 8 1.301
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.298
OLIG2 oligodendrocyte lineage transcription factor 2 1.294
IL2 interleukin 2 1.292
PRTN3 proteinase 3 1.283
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 1.28
BAX BCL2-associated X protein 1.272
THBD thrombomodulin 1.27
NES nestin 1.27
RANBP2 RAN binding protein 2 1.265
COL4A2 collagen, type IV, alpha 2 1.263
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.259
NF1 neurofibromin 1 1.254
PTH parathyroid hormone 1.253
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 1.253
SYP synaptophysin 1.251
NKRF NFKB repressing factor 1.251
SP6 Sp6 transcription factor 1.249
IL4 interleukin 4 1.247
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.244
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.244
EGFR epidermal growth factor receptor 1.242
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.241
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.236
APP amyloid beta (A4) precursor protein 1.233
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.232
CD99L2 CD99 molecule-like 2 1.231
PCDH10 protocadherin 10 1.225
TGFB1 transforming growth factor, beta 1 1.222
CD99 CD99 molecule 1.222
TLR4 toll-like receptor 4 1.218
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.218
AP4M1 adaptor-related protein complex 4, mu 1 subunit 1.218
TSPAN16 tetraspanin 16 1.217
MYH14 myosin, heavy chain 14, non-muscle 1.217
IL17A interleukin 17A 1.215
CCL2 chemokine (C-C motif) ligand 2 1.214
MB myoglobin 1.212
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.209
KNG1 kininogen 1 1.209
TRIM8 tripartite motif containing 8 1.201
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.201
LRRC30 leucine rich repeat containing 30 1.197
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.193
VCAM1 vascular cell adhesion molecule 1 1.188
ICAM1 intercellular adhesion molecule 1 1.183
GDNF glial cell derived neurotrophic factor 1.183
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 1.182
CSF3 colony stimulating factor 3 (granulocyte) 1.181
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.179
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.176
NTF3 neurotrophin 3 1.174
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 1.172
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.168
FGF2 fibroblast growth factor 2 (basic) 1.165
OCLN occludin 1.165
TP53 tumor protein p53 1.165
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.164
AVP arginine vasopressin 1.164
CD19 CD19 molecule 1.163
CXCL10 chemokine (C-X-C motif) ligand 10 1.159
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.157
PDHX pyruvate dehydrogenase complex, component X 1.155
PTPRC protein tyrosine phosphatase, receptor type, C 1.154
JUN jun proto-oncogene 1.152
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.151
FHL2 four and a half LIM domains 2 1.151
F8 coagulation factor VIII, procoagulant component 1.151
IFNB1 interferon, beta 1, fibroblast 1.148
TPO thyroid peroxidase 1.146
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.146
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.14
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.139
MAP2 microtubule-associated protein 2 1.139
PF4V1 platelet factor 4 variant 1 1.139
SCN1B sodium channel, voltage gated, type I beta subunit 1.133
NOS3 nitric oxide synthase 3 (endothelial cell) 1.132
F9 coagulation factor IX 1.13
MAPT microtubule-associated protein tau 1.124
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.123
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.12
TTC19 tetratricopeptide repeat domain 19 1.111
CALCR calcitonin receptor 1.111
NALCN sodium leak channel, non selective 1.108
TNNI3 troponin I type 3 (cardiac) 1.108
SNAP25 synaptosomal-associated protein, 25kDa 1.106
CREB1 cAMP responsive element binding protein 1 1.106
NOTCH2NLC notch 2 N-terminal like C 1.101
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.099
GLRA1 glycine receptor, alpha 1 1.097
MME membrane metallo-endopeptidase 1.096
DNTT DNA nucleotidylexotransferase 1.087
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.085
RPUSD3 RNA pseudouridylate synthase domain containing 3 1.084
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.081
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.08
UNC13D unc-13 homolog D (C. elegans) 1.079
ADA adenosine deaminase 1.076
FXYD6-FXYD2 FXYD6-FXYD2 readthrough 1.075
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.071
SCN9A sodium channel, voltage gated, type IX alpha subunit 1.069
LTA4H leukotriene A4 hydrolase 1.067
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.065
PECAM1 platelet/endothelial cell adhesion molecule 1 1.063
FOS FBJ murine osteosarcoma viral oncogene homolog 1.063
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.058
FOXG1 forkhead box G1 1.057
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.056
GAP43 growth associated protein 43 1.055
MRPS34 mitochondrial ribosomal protein S34 1.054
HP haptoglobin 1.053
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 1.05
GCG glucagon 1.05
DEPDC5 DEP domain containing 5 1.045
TJP1 tight junction protein 1 1.044
KANK1 KN motif and ankyrin repeat domains 1 1.043
DOCK8 dedicator of cytokinesis 8 1.042
TH tyrosine hydroxylase 1.042
HMOX1 heme oxygenase 1 1.038
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.037
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.037
MRPL44 mitochondrial ribosomal protein L44 1.036
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.035
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.035
NKX2-1 NK2 homeobox 1 1.031
NGRN neugrin, neurite outgrowth associated 1.03
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 1.028
MAOB monoamine oxidase B 1.028
ACAA1 acetyl-CoA acyltransferase 1 1.027
DPP6 dipeptidyl-peptidase 6 1.027
PRF1 perforin 1 (pore forming protein) 1.026
OXT oxytocin/neurophysin I prepropeptide 1.023
NCAM1 neural cell adhesion molecule 1 1.023
PDE10A phosphodiesterase 10A 1.018
CPT2 carnitine palmitoyltransferase 2 1.015
RPUSD4 RNA pseudouridylate synthase domain containing 4 1.013
FASTK Fas-activated serine/threonine kinase 1.012
CLCN2 chloride channel, voltage-sensitive 2 1.01
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.009
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.009
SPAST spastin 1.007
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 1.004
DST dystonin 1.004
SYT1 synaptotagmin I 1.002
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.0