Hemoglobin A, Glycosylated Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description disease cluster belonging to disease group hematological (Genetic Association Database)
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Genes

128 genes associated with the trait Hemoglobin A, Glycosylated in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
TAS2R38 taste receptor, type 2, member 38 2.25185
HK1 hexokinase 1 1.94995
FN3KRP fructosamine 3 kinase related protein 1.5935
GCK glucokinase (hexokinase 4) 1.42541
HFE hemochromatosis 1.40774
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.31551
TMPRSS6 transmembrane protease, serine 6 1.15755
ANK1 ankyrin 1, erythrocytic 1.02893
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.01477
SCRG1 stimulator of chondrogenesis 1 0.982669
G6PC2 glucose-6-phosphatase, catalytic, 2 0.888747
SPTA1 spectrin, alpha, erythrocytic 1 0.820059
ATP11AUN ATP11A upstream neighbor 0.796965
PDE4DIP phosphodiesterase 4D interacting protein 0.721805
ADGRL2 adhesion G protein-coupled receptor L2 0.693321
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.685324
ALK anaplastic lymphoma receptor tyrosine kinase 0.661363
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.649822
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.64828
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.64525
PAPD4 PAP associated domain containing 4 0.631349
MALRD1 MAM and LDL receptor class A domain containing 1 0.588419
GAS2 growth arrest-specific 2 0.575813
BNC2 basonuclin 2 0.571387
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.567838
FGGY FGGY carbohydrate kinase domain containing 0.561547
TRIM16 tripartite motif containing 16 0.552946
GRID1 glutamate receptor, ionotropic, delta 1 0.523739
AQP4-AS1 AQP4 antisense RNA 1 0.502051
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.466119
RTTN rotatin 0.419953
AFF3 AF4/FMR2 family, member 3 0.417855
USP25 ubiquitin specific peptidase 25 0.375888
FKBP6 FK506 binding protein 6, 36kDa 0.373819
KIF1A kinesin family member 1A 0.369504
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.361983
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.345136
ERI3 ERI1 exoribonuclease family member 3 0.339807
TSPEAR thrombospondin-type laminin G domain and EAR repeats 0.332071
RCL1 RNA terminal phosphate cyclase-like 1 0.324292
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 0.321458
CRMP1 collapsin response mediator protein 1 0.319371
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.313306
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene) 0.311427
CPVL carboxypeptidase, vitellogenic-like 0.310838
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.292995
PRR16 proline rich 16 0.283376
TRA T cell receptor alpha locus 0.271342
ZNF786 zinc finger protein 786 0.267638
NRG3 neuregulin 3 0.26579
ATP10A ATPase, class V, type 10A 0.264371
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.262604
PBX2 pre-B-cell leukemia homeobox 2 0.257842
RAB22A RAB22A, member RAS oncogene family 0.255097
COX5A cytochrome c oxidase subunit Va 0.250828
EFNA5 ephrin-A5 0.246453
SHF Src homology 2 domain containing F 0.244541
KCNIP4 Kv channel interacting protein 4 0.237357
ZEB1 zinc finger E-box binding homeobox 1 0.237357
PRDM16 PR domain containing 16 0.232934
ACSF3 acyl-CoA synthetase family member 3 0.229154
SH3RF2 SH3 domain containing ring finger 2 0.227314
MLKL mixed lineage kinase domain-like 0.227288
LRRC74A leucine rich repeat containing 74A 0.207272
RNF17 ring finger protein 17 0.205108
WLS wntless Wnt ligand secretion mediator 0.204067
DCP1B decapping mRNA 1B 0.196123
SPATA13 spermatogenesis associated 13 0.194961
DSCAM Down syndrome cell adhesion molecule 0.194775
RAB31 RAB31, member RAS oncogene family 0.194145
KATNAL1 katanin p60 subunit A-like 1 0.182518
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 0.18239
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.179098
DUOX1 dual oxidase 1 0.174313
WWOX WW domain containing oxidoreductase 0.174107
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.169665
CCDC7 coiled-coil domain containing 7 0.169073
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.164683
PPAP2B phosphatidic acid phosphatase type 2B 0.159142
CHL1 cell adhesion molecule L1-like 0.154886
LAMC3 laminin, gamma 3 0.153785
SALL3 spalt-like transcription factor 3 0.147674
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.145433
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.145153
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 0.142152
ESR2 estrogen receptor 2 (ER beta) 0.139797
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.136523
TRAF5 TNF receptor-associated factor 5 0.134202
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.132743
OLFM1 olfactomedin 1 0.12796
TEKT5 tektin 5 0.127843
DPP6 dipeptidyl-peptidase 6 0.126365
VAT1L vesicle amine transport 1-like 0.122069
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.120012
NRXN3 neurexin 3 0.117545
COL11A1 collagen, type XI, alpha 1 0.116091
SYNE2 spectrin repeat containing, nuclear envelope 2 0.115668
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.112757
RNPS1 RNA binding protein S1, serine-rich domain 0.111577
SQSTM1 sequestosome 1 0.107853
NTSR1 neurotensin receptor 1 (high affinity) 0.106218
ENKUR enkurin, TRPC channel interacting protein 0.105099
SELL selectin L 0.102061
NPAS3 neuronal PAS domain protein 3 0.098487
NLRP13 NLR family, pyrin domain containing 13 0.09819
ALAD aminolevulinate dehydratase 0.097641
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.093314
SMC1B structural maintenance of chromosomes 1B 0.093099
ITGA1 integrin, alpha 1 0.090421
COL6A4P2 collagen, type VI, alpha 4 pseudogene 2 0.089919
RIBC2 RIB43A domain with coiled-coils 2 0.089684
TMEM161A transmembrane protein 161A 0.087068
LRP1B low density lipoprotein receptor-related protein 1B 0.086614
RASAL1 RAS protein activator like 1 (GAP1 like) 0.084518
PVT1 Pvt1 oncogene (non-protein coding) 0.08379
ETV6 ets variant 6 0.083082
CD22 CD22 molecule 0.082716
LRRC32 leucine rich repeat containing 32 0.081244
STAP1 signal transducing adaptor family member 1 0.080557
C1ORF162 chromosome 1 open reading frame 162 0.06688
MAP2K4 mitogen-activated protein kinase kinase 4 0.064591
WDR77 WD repeat domain 77 0.063175
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.063175
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.062503
EXOSC2 exosome component 2 0.06209
CD44 CD44 molecule (Indian blood group) 0.060479
SHISA6 shisa family member 6 0.059931
IQSEC1 IQ motif and Sec7 domain 1 0.054345