Hemolytic-Uremic Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Xref MGI. (Human Disease Ontology, DOID_12554)
External Link https://www.disgenet.org/browser/0/1/0/C0019061
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Genes

105 genes associated with the disease Hemolytic-Uremic Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR3 atypical chemokine receptor 3
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALB albumin
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APCS amyloid P component, serum
AZIN2 antizyme inhibitor 2
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4BPA complement component 4 binding protein, alpha
CADM1 cell adhesion molecule 1
CAPG capping protein (actin filament), gelsolin-like
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CCR2 chemokine (C-C motif) receptor 2
CD22 CD22 molecule
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CDA cytidine deaminase
CFB complement factor B
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR3 complement factor H-related 3
CFHR5 complement factor H-related 5
CFI complement factor I
CLEC1B C-type lectin domain family 1, member B
CLU clusterin
COX1
CPB2 carboxypeptidase B2 (plasma)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DBR1 debranching RNA lariats 1
DESI1 desumoylating isopeptidase 1
DGKE diacylglycerol kinase, epsilon 64kDa
EDN1 endothelin 1
EPO erythropoietin
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FGF2 fibroblast growth factor 2 (basic)
FHL1 four and a half LIM domains 1
GADL1 glutamate decarboxylase-like 1
GRAP2 GRB2-related adaptor protein 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
IFNB1 interferon, beta 1, fibroblast
IL10 interleukin 10
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL4R interleukin 4 receptor
IL6 interleukin 6
LIPG lipase, endothelial
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MATK megakaryocyte-associated tyrosine kinase
MCHR2 melanin-concentrating hormone receptor 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NLE1 notchless homolog 1 (Drosophila)
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5C2 5'-nucleotidase, cytosolic II
PCSK5 proprotein convertase subtilisin/kexin type 5
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLG plasminogen
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PRDX1 peroxiredoxin 1
RAB7B RAB7B, member RAS oncogene family
REN renin
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SH3BP4 SH3-domain binding protein 4
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35G1 solute carrier family 35, member G1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STX1A syntaxin 1A (brain)
STX2 syntaxin 2
SUMF2 sulfatase modifying factor 2
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TNF tumor necrosis factor
TP53 tumor protein p53
TRIM25 tripartite motif containing 25
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VWF von Willebrand factor
WT1 Wilms tumor 1
ZFP36 ZFP36 ring finger protein