Hemorrhage Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels (Mammalian Phenotype Ontology, MP_0001914)
External Link https://www.disgenet.org/browser/0/1/0/C0585110
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Genes

293 genes associated with the disease Hemorrhage in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAD8 acyl-CoA dehydrogenase family, member 8
ACP2 acid phosphatase 2, lysosomal
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
AGRP agouti related neuropeptide
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANGPT1 angiopoietin 1
ANK2 ankyrin 2, neuronal
ANO6 anoctamin 6
ANPEP alanyl (membrane) aminopeptidase
ANXA5 annexin A5
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
AQP6 aquaporin 6, kidney specific
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSF arylsulfatase F
ARTN artemin
ATM ATM serine/threonine kinase
ATRAID all-trans retinoic acid-induced differentiation factor
AZIN2 antizyme inhibitor 2
BAG3 BCL2-associated athanogene 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BST2 bone marrow stromal cell antigen 2
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CALCA calcitonin-related polypeptide alpha
CAPN2 calpain 2, (m/II) large subunit
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD209 CD209 molecule
CD24 CD24 molecule
CD34 CD34 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDSN corneodesmosin
CFH complement factor H
CFL1 cofilin 1 (non-muscle)
CLEC10A C-type lectin domain family 10, member A
CLEC4G C-type lectin domain family 4, member G
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COX2
CP ceruloplasmin (ferroxidase)
CPVL carboxypeptidase, vitellogenic-like
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DISP1 dispatched homolog 1 (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGR3 early growth response 3
EIF4E eukaryotic translation initiation factor 4E
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FAM134B family with sequence similarity 134, member B
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FOLR1 folate receptor 1 (adult)
FOLR2 folate receptor 2 (fetal)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXP3 forkhead box P3
FUZ fuzzy planar cell polarity protein
FZD4 frizzled class receptor 4
GADL1 glutamate decarboxylase-like 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAS6 growth arrest-specific 6
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GORASP1 golgi reassembly stacking protein 1, 65kDa
GP2 glycoprotein 2 (zymogen granule membrane)
GP5 glycoprotein V (platelet)
GPR151 G protein-coupled receptor 151
GPRC6A G protein-coupled receptor, class C, group 6, member A
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GTPBP1 GTP binding protein 1
GYPC glycophorin C (Gerbich blood group)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HCST hematopoietic cell signal transducer
HHAT hedgehog acyltransferase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HM13 histocompatibility (minor) 13
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HP haptoglobin
HPSE heparanase
HSPA14 heat shock 70kDa protein 14
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
IFI30 interferon, gamma-inducible protein 30
IFIH1 interferon induced with helicase C domain 1
IFITM3 interferon induced transmembrane protein 3
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA17 interferon, alpha 17
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL2RA interleukin 2 receptor, alpha
IL31RA interleukin 31 receptor A
IL33 interleukin 33
IL34 interleukin 34
IL4 interleukin 4
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
IVNS1ABP influenza virus NS1A binding protein
JAG2 jagged 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP1 lysosomal-associated membrane protein 1
LAMP3 lysosomal-associated membrane protein 3
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LNPK lunapark, ER junction formation factor
LPAR3 lysophosphatidic acid receptor 3
LSAMP limbic system-associated membrane protein
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAVS mitochondrial antiviral signaling protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCHR2 melanin-concentrating hormone receptor 2
MERTK MER proto-oncogene, tyrosine kinase
MGAM maltase-glucoamylase
MMRN1 multimerin 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MRC1 mannose receptor, C type 1
MRGPRX1 MAS-related GPR, member X1
MRGPRX3 MAS-related GPR, member X3
MRGPRX4 MAS-related GPR, member X4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
MYOM2 myomesin 2
NAAA N-acylethanolamine acid amidase
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NLRP3 NLR family, pyrin domain containing 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPC1 Niemann-Pick disease, type C1
NTPCR nucleoside-triphosphatase, cancer-related
NUSAP1 nucleolar and spindle associated protein 1
OXER1 oxoeicosanoid (OXE) receptor 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PDPN podoplanin
PELI1 pellino E3 ubiquitin protein ligase 1
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLG plasminogen
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POMC proopiomelanocortin
PON1 paraoxonase 1
PRDM6 PR domain containing 6
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPA protein phosphatase 2 phosphatase activator
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB11A RAB11A, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBBP6 retinoblastoma binding protein 6
RBM45 RNA binding motif protein 45
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RILP Rab interacting lysosomal protein
RLN3 relaxin 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A10 S100 calcium binding protein A10
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SARS1 seryl-tRNA synthetase 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDC1 syndecan 1
SEPT8 septin 8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPD surfactant protein D
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SI sucrase-isomaltase (alpha-glucosidase)
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMYD3 SET and MYND domain containing 3
SOCS1 suppressor of cytokine signaling 1
SRSF1 serine/arginine-rich splicing factor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAU1 staufen double-stranded RNA binding protein 1
STX1A syntaxin 1A (brain)
STX2 syntaxin 2
SYT1 synaptotagmin I
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMELESS timeless circadian clock
TLR10 toll-like receptor 10
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TM7SF2 transmembrane 7 superfamily member 2
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TOP1 topoisomerase (DNA) I
TPCN2 two pore segment channel 2
TPI1 triosephosphate isomerase 1
TPPP2 tubulin polymerization-promoting protein family member 2
TRIM2 tripartite motif containing 2
TRIM33 tripartite motif containing 33
TRIM6 tripartite motif containing 6
TSG101 tumor susceptibility 101
TTC37 tetratricopeptide repeat domain 37
TTC7A tetratricopeptide repeat domain 7A
TYRO3 TYRO3 protein tyrosine kinase
TYROBP TYRO protein tyrosine kinase binding protein
UBE2I ubiquitin-conjugating enzyme E2I
UROD uroporphyrinogen decarboxylase
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAC14 Vac14 homolog (S. cerevisiae)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHLL von Hippel-Lindau tumor suppressor-like
VTN vitronectin
WNK1 WNK lysine deficient protein kinase 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF197 zinc finger protein 197
ZNF415 zinc finger protein 415
ZNF645 zinc finger protein 645
ZUFSP zinc finger with UFM1-specific peptidase domain