Heparin-Induced Thrombocytopenia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Low platelet count following administration of unfractionated or (less commonly) low-molecular weight heparin. (Human Phenotype Ontology, HP_0011874)
External Link https://www.disgenet.org/browser/0/1/0/C0877016
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Genes

42 genes associated with the disease Heparin-Induced Thrombocytopenia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACLY ATP citrate lyase
ALB albumin
ANXA5 annexin A5
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
BDNF brain-derived neurotrophic factor
DAO D-amino-acid oxidase
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FN1 fibronectin 1
GP6 glycoprotein VI (platelet)
GPR65 G protein-coupled receptor 65
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HNMT histamine N-methyltransferase
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCPH1 microcephalin 1
MMP2 matrix metallopeptidase 2
MSR1 macrophage scavenger receptor 1
NF2 neurofibromin 2 (merlin)
PADI4 peptidyl arginine deiminase, type IV
PF4 platelet factor 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTPRJ protein tyrosine phosphatase, receptor type, J
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SRA1 steroid receptor RNA activator 1
TGFB1 transforming growth factor, beta 1
UBASH3B ubiquitin associated and SH3 domain containing B
YES1 YES proto-oncogene 1, Src family tyrosine kinase