Hepatitis A Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus, which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice. (Human Disease Ontology, DOID_12549)
External Link https://www.disgenet.org/browser/0/1/0/C0019159
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Genes

415 genes associated with the disease Hepatitis A in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACE angiotensin I converting enzyme
ACOT7 acyl-CoA thioesterase 7
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHI1 Abelson helper integration site 1
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIRE autoimmune regulator
AKR1D1 aldo-keto reductase family 1, member D1
ALB albumin
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMELY amelogenin, Y-linked
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOB apolipoprotein B
APOE apolipoprotein E
ARC activity-regulated cytoskeleton-associated protein
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP24 Rho GTPase activating protein 24
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARTN artemin
ATG7 autophagy related 7
B2M beta-2-microglobulin
BBC3 BCL2 binding component 3
BCAR1 breast cancer anti-estrogen resistance 1
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BRD2 bromodomain containing 2
BTNL2 butyrophilin-like 2
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCDC88A coiled-coil domain containing 88A
CCL16 chemokine (C-C motif) ligand 16
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CD1D CD1d molecule
CD200 CD200 molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD4 CD4 molecule
CD58 CD58 molecule
CD5L CD5 molecule-like
CD68 CD68 molecule
CD81 CD81 molecule
CD99 CD99 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDSN corneodesmosin
CLDN1 claudin 1
CLDN3 claudin 3
CLDN7 claudin 7
CLOCK clock circadian regulator
CLTC clathrin, heavy chain (Hc)
CLU clusterin
CNOT3 CCR4-NOT transcription complex, subunit 3
COL11A2 collagen, type XI, alpha 2
COL15A1 collagen, type XV, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COMMD1 copper metabolism (Murr1) domain containing 1
COMP cartilage oligomeric matrix protein
COX2
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPA4 carboxypeptidase A4
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRLF1 cytokine receptor-like factor 1
CRNKL1 crooked neck pre-mRNA splicing factor 1
CRP C-reactive protein, pentraxin-related
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCTN4 dynactin 4 (p62)
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DLAT dihydrolipoamide S-acetyltransferase
DMBT1 deleted in malignant brain tumors 1
DPP4 dipeptidyl-peptidase 4
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EIF4E eukaryotic translation initiation factor 4E
EMB embigin
EPCAM epithelial cell adhesion molecule
EPHA1 EPH receptor A1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERVW-1 endogenous retrovirus group W, member 1
ESM1 endothelial cell-specific molecule 1
ESR1 estrogen receptor 1
ESRRB estrogen-related receptor beta
EXT1 exostosin glycosyltransferase 1
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FBL fibrillarin
FGL2 fibrinogen-like 2
FHL5 four and a half LIM domains 5
FKBP11 FK506 binding protein 11, 19 kDa
FLNA filamin A, alpha
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FOXP3 forkhead box P3
FTO fat mass and obesity associated
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GGTLC1 gamma-glutamyltransferase light chain 1
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
GOLM1 golgi membrane protein 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPC3 glypican 3
GPR39 G protein-coupled receptor 39
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
GSPT1 G1 to S phase transition 1
GSR glutathione reductase
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HAS1 hyaluronan synthase 1
HAS3 hyaluronan synthase 3
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HPGDS hematopoietic prostaglandin D synthase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICOS inducible T-cell co-stimulator
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL11 interleukin 11
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17C interleukin 17C
IL17D interleukin 17D
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL34 interleukin 34
IL37 interleukin 37
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRS1 insulin receptor substrate 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
IVNS1ABP influenza virus NS1A binding protein
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDM6B lysine (K)-specific demethylase 6B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF1B kinesin family member 1B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLHL1 kelch-like family member 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT18 keratin 18, type I
KRT20 keratin 20, type I
KRT23 keratin 23, type I
KRT7 keratin 7, type II
LAG3 lymphocyte-activation gene 3
LAMP3 lysosomal-associated membrane protein 3
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
LSAMP limbic system-associated membrane protein
LTBP2 latent transforming growth factor beta binding protein 2
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MARCKS myristoylated alanine-rich protein kinase C substrate
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MAVS mitochondrial antiviral signaling protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MLH1 mutL homolog 1
MLKL mixed lineage kinase domain-like
MRC1 mannose receptor, C type 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSC musculin
MT-CYB cytochrome b
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYDGF myeloid-derived growth factor
MYOM2 myomesin 2
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBAS neuroblastoma amplified sequence
NCAM1 neural cell adhesion molecule 1
NCKIPSD NCK interacting protein with SH3 domain
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NELFE negative elongation factor complex member E
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSG1 neuron specific gene family member 1
NTSR1 neurotensin receptor 1 (high affinity)
NUP62 nucleoporin 62kDa
OGG1 8-oxoguanine DNA glycosylase
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OPRM1 opioid receptor, mu 1
OXA1L oxidase (cytochrome c) assembly 1-like
PAEP progestagen-associated endometrial protein
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDLIM5 PDZ and LIM domain 5
PGAM5 phosphoglycerate mutase family member 5
PHB prohibitin
PIGR polymeric immunoglobulin receptor
PKD2L1 polycystic kidney disease 2-like 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PML promyelocytic leukemia
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PON1 paraoxonase 1
POSTN periostin, osteoblast specific factor
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PROM1 prominin 1
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAG2 recombination activating gene 2
RAP1A RAP1A, member of RAS oncogene family
RBM45 RNA binding motif protein 45
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHD Rh blood group, D antigen
RHOF ras homolog family member F (in filopodia)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RIT2 Ras-like without CAAX 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RO60 Ro60, Y RNA binding protein
RRM2 ribonucleotide reductase M2
S100A4 S100 calcium binding protein A4
SARS1 seryl-tRNA synthetase 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SETBP1 SET binding protein 1
SETD2 SET domain containing 2
SGMS1 sphingomyelin synthase 1
SIRT1 sirtuin 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SON SON DNA binding protein
SOX11 SRY (sex determining region Y)-box 11
SPAG9 sperm associated antigen 9
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYCE1L synaptonemal complex central element protein 1-like
SYT1 synaptotagmin I
TBX21 T-box 21
TCEAL1 transcription elongation factor A (SII)-like 1
TDO2 tryptophan 2,3-dioxygenase
TFEB transcription factor EB
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THRA thyroid hormone receptor, alpha
TIMELESS timeless circadian clock
TIMP2 TIMP metallopeptidase inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TIPE2 TNF alpha induced protein 8 like 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP73 tumor protein p73
TREM2 triggering receptor expressed on myeloid cells 2
TRIM21 tripartite motif containing 21
TRIM55 tripartite motif containing 55
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TSLP thymic stromal lymphopoietin
TXN thioredoxin
TYRO3 TYRO3 protein tyrosine kinase
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2K ubiquitin-conjugating enzyme E2K
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UMOD uromodulin
UROD uroporphyrinogen decarboxylase
VASN vasorin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VTN vitronectin
WNK1 WNK lysine deficient protein kinase 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1