Hepatoblastoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0854796
Similar Terms
Downloads & Tools

Genes

407 genes associated with the disease Hepatoblastoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACOX2 acyl-CoA oxidase 2, branched chain
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDOC aldolase C, fructose-bisphosphate
ALPG alkaline phosphatase, germ cell
AMER1 APC membrane recruitment protein 1
ANLN anillin, actin binding protein
ANPEP alanyl (membrane) aminopeptidase
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOM apolipoprotein M
APRT adenine phosphoribosyltransferase
ARG1 arginase 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASRGL1 asparaginase like 1
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1
ATM ATM serine/threonine kinase
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATRAID all-trans retinoic acid-induced differentiation factor
AXIN1 axin 1
AXIN2 axin 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BRCA2 breast cancer 2, early onset
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C3 complement component 3
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CADM1 cell adhesion molecule 1
CALCA calcitonin-related polypeptide alpha
CAPN3 calpain 3, (p94)
CAPRIN2 caprin family member 2
CARM1 coactivator-associated arginine methyltransferase 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCK cholecystokinin
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE1 cyclin E1
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CDC20B cell division cycle 20B
CDC25C cell division cycle 25C
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELF1 CUGBP, Elav-like family member 1
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIB1 calcium and integrin binding 1 (calmyrin)
CIB2 calcium and integrin binding family member 2
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLDN1 claudin 1
CLDN2 claudin 2
CLDN7 claudin 7
COL18A1 collagen, type XVIII, alpha 1
COX1
CSK c-src tyrosine kinase
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSL cathepsin L
CXCL5 chemokine (C-X-C motif) ligand 5
CXCR2 chemokine (C-X-C motif) receptor 2
CXXC4 CXXC finger protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DCTN6 dynactin 6
DERL2 derlin 2
DERL3 derlin 3
DESI1 desumoylating isopeptidase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DNASE1 deoxyribonuclease I
DNLZ DNL-type zinc finger
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPEP1 dipeptidase 1 (renal)
DRAM1 DNA-damage regulated autophagy modulator 1
DVL2 dishevelled segment polarity protein 2
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
ENG endoglin
EP300 E1A binding protein p300
EPCAM epithelial cell adhesion molecule
EPHB2 EPH receptor B2
EPO erythropoietin
EPOR erythropoietin receptor
EPT1 ethanolaminephosphotransferase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESRRB estrogen-related receptor beta
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FADD Fas (TNFRSF6)-associated via death domain
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FN1 fibronectin 1
FOXG1 forkhead box G1
FOXM1 forkhead box M1
FOXP1 forkhead box P1
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA4 GATA binding protein 4
GC group-specific component (vitamin D binding protein)
GCG glucagon
GJB2 gap junction protein, beta 2, 26kDa
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GLUL glutamate-ammonia ligase
GMPS guanine monphosphate synthase
GNMT glycine N-methyltransferase
GOLM1 golgi membrane protein 1
GPC3 glypican 3
GPC4 glypican 4
GPR162 G protein-coupled receptor 162
GREB1 growth regulation by estrogen in breast cancer 1
GSTK1 glutathione S-transferase kappa 1
HAL histidine ammonia-lyase
HAMP hepcidin antimicrobial peptide
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HLF hepatic leukemia factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXD13 homeobox D13
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPG2 heparan sulfate proteoglycan 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL25 interleukin 25
IL33R interleukin 33 receptor
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
ING3 inhibitor of growth family, member 3
INSR insulin receptor
IQGAP2 IQ motif containing GTPase activating protein 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KEAP1 kelch-like ECH-associated protein 1
KLK4 kallikrein-related peptidase 4
KRAS Kirsten rat sarcoma viral oncogene homolog
KREMEN1 kringle containing transmembrane protein 1
KRT19 keratin 19, type I
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LIF leukemia inhibitory factor
LINC01314 long intergenic non-protein coding RNA 1314
LPAR1 lysophosphatidic acid receptor 1
LPIN1 lipin 1
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCM7 minichromosome maintenance complex component 7
MCM9 minichromosome maintenance complex component 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MPO myeloperoxidase
MRPL58 mitochondrial ribosomal protein L58
MSH2 mutS homolog 2
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT1B metallothionein 1B
MT1F metallothionein 1F
MT1G metallothionein 1G
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYDGF myeloid-derived growth factor
NANOG Nanog homeobox
NDRG2 NDRG family member 2
NECTIN1 nectin cell adhesion molecule 1
NEUROD1 neuronal differentiation 1
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NKD1 naked cuticle homolog 1 (Drosophila)
NLRP3 NLR family, pyrin domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR5A2 nuclear receptor subfamily 5, group A, member 2
OTC ornithine carbamoyltransferase
OXA1L oxidase (cytochrome c) assembly 1-like
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARP1 poly (ADP-ribose) polymerase 1
PCLAF PCNA clamp associated factor
PCNA proliferating cell nuclear antigen
PCSK9 proprotein convertase subtilisin/kexin type 9
PFAS phosphoribosylformylglycinamidine synthase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PNPLA2 patatin-like phospholipase domain containing 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG polymerase (DNA directed), gamma
POR P450 (cytochrome) oxidoreductase
POSTN periostin, osteoblast specific factor
POTEF POTE ankyrin domain family, member F
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPAT phosphoribosyl pyrophosphate amidotransferase
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRDX6 peroxiredoxin 6
PROM1 prominin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPA protein phosphatase 2 phosphatase activator
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RALY RALY heterogeneous nuclear ribonucleoprotein
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RGN regucalcin
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPL36A ribosomal protein L36a
RRM1 ribonucleotide reductase M1
S100A6 S100 calcium binding protein A6
SAR1B secretion associated, Ras related GTPase 1B
SAV1 salvador family WW domain containing protein 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETBP1 SET binding protein 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFRP1 secreted frizzled-related protein 1
SHBG sex hormone-binding globulin
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT1 sirtuin 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A18 solute carrier family 22, member 18
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC38A1 solute carrier family 38, member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SOX2 SRY (sex determining region Y)-box 2
SPOP speckle-type POZ protein
SREBF2 sterol regulatory element binding transcription factor 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF1 serine/arginine-rich splicing factor 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TAT tyrosine aminotransferase
TAZ tafazzin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX3 T-box 3
TEAD2 TEA domain family member 2
TEAD4 TEA domain family member 4
TEK TEK tyrosine kinase, endothelial
TEP1 telomerase-associated protein 1
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THPO thrombopoietin
THY1 Thy-1 cell surface antigen
TICAM2 toll-like receptor adaptor molecule 2
TLR4 toll-like receptor 4
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TPPP2 tubulin polymerization-promoting protein family member 2
TTC37 tetratricopeptide repeat domain 37
TTR transthyretin
TUG1 taurine up-regulated 1 (non-protein coding)
TXNIP thioredoxin interacting protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBE2I ubiquitin-conjugating enzyme E2I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UROD uroporphyrinogen decarboxylase
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
WDR20 WD repeat domain 20
WNT1 wingless-type MMTV integration site family, member 1
WWTR1 WW domain containing transcription regulator 1
XDH xanthine dehydrogenase
YAP1 Yes-associated protein 1
YY1 YY1 transcription factor
ZEB1 zinc finger E-box binding homeobox 1
ZNF197 zinc finger protein 197