Hepatocellular Adenoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A benign epithelial neoplasm arising from the hepatocytes. Grossly, it appears as a soft, round mass which often contains areas of hemorrhage and necrosis. Morphologically, the neoplastic cells resemble normal hepatocytes and form plates separated by sinusoids. Most patients have a history of contraceptive or anabolic steroids use. (Experimental Factor Ontology, EFO_0000762)
External Link https://www.disgenet.org/browser/0/1/0/C0206669
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Genes

107 genes associated with the disease Hepatocellular Adenoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
A2M alpha-2-macroglobulin
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACTB actin, beta
AFP alpha-fetoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA2 annexin A2
AOC1 amine oxidase, copper containing 1
APC adenomatous polyposis coli
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASS1 argininosuccinate synthase 1
AZIN2 antizyme inhibitor 2
AZU1 azurocidin 1
BHLHE22 basic helix-loop-helix family, member e22
BLK BLK proto-oncogene, Src family tyrosine kinase
CARM1 coactivator-associated arginine methyltransferase 1
CCND2 cyclin D2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEL carboxyl ester lipase
CNBP CCHC-type zinc finger, nucleic acid binding protein
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
EGF epidermal growth factor
FABP1 fatty acid binding protein 1, liver
FRK fyn-related Src family tyrosine kinase
FXN frataxin
G6PC glucose-6-phosphatase, catalytic subunit
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADL1 glutamate decarboxylase-like 1
GCK glucokinase (hexokinase 4)
GFAP glial fibrillary acidic protein
GLUL glutamate-ammonia ligase
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPC3 glypican 3
HDLBP high density lipoprotein binding protein
HEBP1 heme binding protein 1
HMGB1 high mobility group box 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
IGF2R insulin-like growth factor 2 receptor
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INS insulin
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KLF11 Kruppel-like factor 11
KLHL1 kelch-like family member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC105371045 uncharacterized LOC105371045
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MLXIPL MLX interacting protein-like
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NEUROD1 neuronal differentiation 1
NFE2L2 nuclear factor, erythroid 2-like 2
NOTCH2 notch 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PAX4 paired box 4
PDGFC platelet derived growth factor C
PDX1 pancreatic and duodenal homeobox 1
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RSPO2 R-spondin 2
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SHBG sex hormone-binding globulin
SLBP stem-loop binding protein
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SPTB spectrin, beta, erythrocytic
SPTBN2 spectrin, beta, non-erythrocytic 2
SREBF1 sterol regulatory element binding transcription factor 1
SSTR2 somatostatin receptor 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYCE1L synaptonemal complex central element protein 1-like
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TMEM70 transmembrane protein 70
TMPRSS13 transmembrane protease, serine 13
TP53 tumor protein p53
TRPV2 transient receptor potential cation channel, subfamily V, member 2
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
WNT1 wingless-type MMTV integration site family, member 1