Her2-Negative Breast Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4733095
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Genes

145 genes associated with the disease Her2-Negative Breast Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADGRF1 adhesion G protein-coupled receptor F1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANO1 anoctamin 1, calcium activated chloride channel
ANXA2 annexin A2
ANXA7 annexin A7
AR androgen receptor
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATF4 activating transcription factor 4
BCAR1 breast cancer anti-estrogen resistance 1
BID BH3 interacting domain death agonist
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTG2 BTG family, member 2
CA12 carbonic anhydrase XII
CAPN2 calpain 2, (m/II) large subunit
CCND1 cyclin D1
CCNE1 cyclin E1
CCNE2 cyclin E2
CCR2 chemokine (C-C motif) receptor 2
CD274 CD274 molecule
CD44 CD44 molecule (Indian blood group)
CDK4 cyclin-dependent kinase 4
COL11A2 collagen, type XI, alpha 2
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DCTN6 dynactin 6
DOCK1 dedicator of cytokinesis 1
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FABP7 fatty acid binding protein 7, brain
FANCF Fanconi anemia, complementation group F
FASN fatty acid synthase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGFR2 fibroblast growth factor receptor 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXA1 forkhead box A1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GJA1 gap junction protein, alpha 1, 43kDa
GPN3 GPN-loop GTPase 3
GRB2 growth factor receptor-bound protein 2
HDAC9 histone deacetylase 9
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HUNK hormonally up-regulated Neu-associated kinase
IFI27 interferon, alpha-inducible protein 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IL24 interleukin 24
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
KDM5A lysine (K)-specific demethylase 5A
KIF1B kinesin family member 1B
KIF2C kinesin family member 2C
KMT2C lysine (K)-specific methyltransferase 2C
KRT16 keratin 16, type I
KRT19 keratin 19, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3 lectin, galactoside-binding, soluble, 3
LIN28A lin-28 homolog A (C. elegans)
MAGED2 melanoma antigen family D2
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MMP11 matrix metallopeptidase 11
MSN moesin
MTSS1 metastasis suppressor 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA2 nuclear receptor coactivator 2
NECTIN4 nectin cell adhesion molecule 4
NOTCH1 notch 1
NPAS2 neuronal PAS domain protein 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRF1 nuclear respiratory factor 1
NRG1 neuregulin 1
NUP43 nucleoporin 43kDa
OSM oncostatin M
PARP1 poly (ADP-ribose) polymerase 1
PCGF2 polycomb group ring finger 2
PCNA proliferating cell nuclear antigen
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG2 recombination activating gene 2
RARA retinoic acid receptor, alpha
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RMDN3 regulator of microtubule dynamics 3
ROR1 receptor tyrosine kinase-like orphan receptor 1
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SCAMP1 secretory carrier membrane protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN2 sestrin 2
SH3GL1 SH3-domain GRB2-like 1
SIRT1 sirtuin 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TADA3 transcriptional adaptor 3
TBK1 TANK-binding kinase 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM2 toll-like receptor adaptor molecule 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRIO trio Rho guanine nucleotide exchange factor
UGCG UDP-glucose ceramide glucosyltransferase
USP9X ubiquitin specific peptidase 9, X-linked
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1