Her2-Positive Carcinoma Of Breast Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1960398
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Genes

264 genes associated with the disease Her2-Positive Carcinoma Of Breast in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM10 ADAM metallopeptidase domain 10
ADGRF1 adhesion G protein-coupled receptor F1
ADRB2 adrenoceptor beta 2, surface
AK4 adenylate kinase 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALK anaplastic lymphoma receptor tyrosine kinase
ANXA1 annexin A1
AOC1 amine oxidase, copper containing 1
AR androgen receptor
AREG amphiregulin
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATR ATR serine/threonine kinase
AXL AXL receptor tyrosine kinase
BAG1 BCL2-associated athanogene
BARD1 BRCA1 associated RING domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
CA12 carbonic anhydrase XII
CAPN2 calpain 2, (m/II) large subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCK cholecystokinin
CCL5 chemokine (C-C motif) ligand 5
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE2 cyclin E2
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CD274 CD274 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDC37 cell division cycle 37
CDCP1 CUB domain containing protein 1
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CLCN3 chloride channel, voltage-sensitive 3
COL11A2 collagen, type XI, alpha 2
COX2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL3 cullin 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCTN6 dynactin 6
DOCK1 dedicator of cytokinesis 1
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
ECD ecdysoneless homolog (Drosophila)
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EML4 echinoderm microtubule associated protein like 4
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPHA5 EPH receptor A5
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
ETV4 ets variant 4
EZR ezrin
FABP7 fatty acid binding protein 7, brain
FANCF Fanconi anemia, complementation group F
FAS Fas cell surface death receptor
FASN fatty acid synthase
FAT1 FAT atypical cadherin 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FEN1 flap structure-specific endonuclease 1
FES FES proto-oncogene, tyrosine kinase
FGF5 fibroblast growth factor 5
FGFR1 fibroblast growth factor receptor 1
FLT4 fms-related tyrosine kinase 4
FOXF2 forkhead box F2
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FST follistatin
GAB2 GRB2-associated binding protein 2
GCLC glutamate-cysteine ligase, catalytic subunit
GDF2 growth differentiation factor 2
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GPN3 GPN-loop GTPase 3
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GSDMB gasdermin B
GSK3B glycogen synthase kinase 3 beta
H2AX H2A.X variant histone
HDAC3 histone deacetylase 3
HDAC9 histone deacetylase 9
HOXC4 homeobox C4
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HUNK hormonally up-regulated Neu-associated kinase
IFI27 interferon, alpha-inducible protein 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL15 interleukin 15
IL24 interleukin 24
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRS1 insulin receptor substrate 1
KCTD10 potassium channel tetramerization domain containing 10
KDM5A lysine (K)-specific demethylase 5A
KIF2C kinesin family member 2C
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LIN28A lin-28 homolog A (C. elegans)
LMO4 LIM domain only 4
LYPLA1 lysophospholipase I
MACC1 metastasis associated in colon cancer 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MCL1 myeloid cell leukemia 1
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKI67 marker of proliferation Ki-67
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPZL1 myelin protein zero-like 1
MST1R macrophage stimulating 1 receptor
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
NBN nibrin
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NMU neuromedin U
NOTCH1 notch 1
NOTCH2 notch 2
NPAS2 neuronal PAS domain protein 2
NRF1 nuclear respiratory factor 1
NRG1 neuregulin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP43 nucleoporin 43kDa
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAEP progestagen-associated endometrial protein
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARP1 poly (ADP-ribose) polymerase 1
PCGF2 polycomb group ring finger 2
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD2L1 polycystic kidney disease 2-like 1
PLA2G16 phospholipase A2, group XVI
PLCG1 phospholipase C, gamma 1
PLK1 polo-like kinase 1
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPA protein phosphatase 2 phosphatase activator
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRO protein tyrosine phosphatase, receptor type, O
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG2 recombination activating gene 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHOJ ras homolog family member J
RMDN3 regulator of microtubule dynamics 3
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6 ribosomal protein S6
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SCAMP1 secretory carrier membrane protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERTAD1 SERTA domain containing 1
SFMBT2 Scm-like with four mbt domains 2
SH3GL1 SH3-domain GRB2-like 1
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC25A43 solute carrier family 25, member 43
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SRY sex determining region Y
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
TADA3 transcriptional adaptor 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAZ tafazzin
TBK1 TANK-binding kinase 1
TEAD4 TEA domain family member 4
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM2 toll-like receptor adaptor molecule 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TYMS thymidylate synthetase
UGCG UDP-glucose ceramide glucosyltransferase
USP9X ubiquitin specific peptidase 9, X-linked
VEGFA vascular endothelial growth factor A
VMP1 vacuole membrane protein 1
WBP2 WW domain binding protein 2
YAP1 Yes-associated protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZFP36 ZFP36 ring finger protein