| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hesperidin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.179335 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.092943 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0744283 |
| TXNRD1 | thioredoxin reductase 1 | 0.0723309 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0720478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0585445 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0498446 |
| XPO1 | exportin 1 | 0.0493343 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0471141 |
| MATR3 | matrin 3 | 0.0468345 |
| PCBP2 | poly(rC) binding protein 2 | 0.0452865 |
| TMEM41B | transmembrane protein 41B | 0.044569 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0443179 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0442068 |
| NEK7 | NIMA-related kinase 7 | 0.042975 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0417236 |
| ECT2 | epithelial cell transforming 2 | 0.0411636 |
| KIF5B | kinesin family member 5B | 0.0401258 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0397862 |
| TNPO1 | transportin 1 | 0.0370716 |
| CCNL1 | cyclin L1 | 0.0364006 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0363948 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0357927 |
| VMP1 | vacuole membrane protein 1 | 0.0344437 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0332978 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0326251 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0321322 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0320821 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0318922 |
| YBX1 | Y box binding protein 1 | 0.0311636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0309282 |
| KLHL24 | kelch-like family member 24 | 0.0300319 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0297152 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0291193 |
| WDR43 | WD repeat domain 43 | 0.0290434 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0289967 |
| CPOX | coproporphyrinogen oxidase | 0.0285166 |
| OXR1 | oxidation resistance 1 | 0.0284887 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0283321 |
| ZNF292 | zinc finger protein 292 | 0.0281383 |
| IPO7 | importin 7 | 0.0281146 |
| MED13L | mediator complex subunit 13-like | 0.0277714 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0272706 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0271724 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0269583 |
| TFG | TRK-fused gene | 0.0266751 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.026327 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0262934 |
| TBK1 | TANK-binding kinase 1 | 0.0259637 |
| NCKAP1 | NCK-associated protein 1 | 0.0257173 |
| IL6ST | interleukin 6 signal transducer | 0.0247086 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0246631 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0246554 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0237898 |
| THOC1 | THO complex 1 | 0.0237727 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0233997 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0232521 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.023216 |
| ARRDC3 | arrestin domain containing 3 | 0.0231014 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0228436 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0226789 |
| OGA | O-GlcNAcase | 0.0226507 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0226063 |
| NUP58 | nucleoporin 58 | 0.0225043 |
| ETNK1 | ethanolamine kinase 1 | 0.022486 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0224774 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0223819 |
| TMEM123 | transmembrane protein 123 | 0.0223419 |
| RPLP0 | ribosomal protein, large, P0 | 0.02226 |
| THOC2 | THO complex 2 | 0.0222303 |
| CDK17 | cyclin-dependent kinase 17 | 0.0221927 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0219231 |
| HLTF | helicase-like transcription factor | 0.0217387 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0215659 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0215184 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.021458 |
| MGAT4C | MGAT4 family, member C | 0.0213578 |
| CDK19 | cyclin-dependent kinase 19 | 0.0213573 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0208875 |
| PNN | pinin, desmosome associated protein | 0.0208353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0207646 |
| SET | SET nuclear proto-oncogene | 0.0207372 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0206676 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0203384 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0203083 |
| TPR | translocated promoter region, nuclear basket protein | 0.0202714 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0201486 |
| CENPF | centromere protein F, 350/400kDa | 0.0200688 |
| GASK1B | golgi associated kinase 1B | 0.0197741 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0197121 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0191844 |
| PCM1 | pericentriolar material 1 | 0.0190981 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0190807 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0190748 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0190339 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0188068 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0186505 |
| TNRC6A | trinucleotide repeat containing 6A | 0.018624 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0185862 |
| MRPL3 | mitochondrial ribosomal protein L3 | 0.018464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.176423 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.171254 |
| HMGA2 | high mobility group AT-hook 2 | -0.126944 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.111 |
| TMSB10 | thymosin beta 10 | -0.0813331 |
| EHBP1 | EH domain binding protein 1 | -0.0691378 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0616267 |
| PCDH7 | protocadherin 7 | -0.0587328 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0556213 |
| INTS6 | integrator complex subunit 6 | -0.0547652 |
| ZNF804A | zinc finger protein 804A | -0.0532269 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.052474 |
| ADIPOR2 | adiponectin receptor 2 | -0.0473141 |
| EGR1 | early growth response 1 | -0.0448535 |
| ACTG1 | actin gamma 1 | -0.042385 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0419944 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0413686 |
| CUX1 | cut-like homeobox 1 | -0.0411358 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0382831 |
| TPI1 | triosephosphate isomerase 1 | -0.0371096 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0361452 |
| CMIP | c-Maf inducing protein | -0.0358904 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0349473 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0345116 |
| ASPH | aspartate beta-hydroxylase | -0.0343006 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0342431 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0332964 |
| NHSL1 | NHS-like 1 | -0.0331384 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0330435 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0326515 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0325101 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0319494 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0317625 |
| LRRC23 | leucine rich repeat containing 23 | -0.0316869 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0311756 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0302854 |
| RASAL2 | RAS protein activator like 2 | -0.0296686 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286225 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0286216 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0284297 |
| NEBL | nebulette | -0.0283629 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0283302 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0278454 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0277842 |
| NABP1 | nucleic acid binding protein 1 | -0.0276939 |
| RPL35A | ribosomal protein L35a | -0.0276415 |
| AHNAK | AHNAK nucleoprotein | -0.0259769 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0258097 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0254056 |
| PCDH9 | protocadherin 9 | -0.0247677 |
| MTAP | methylthioadenosine phosphorylase | -0.0247503 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0245126 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0240025 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0237309 |
| HDAC9 | histone deacetylase 9 | -0.023335 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0231158 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0230396 |
| DST | dystonin | -0.0230369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0230161 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0229399 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0229241 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0227198 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0225877 |
| JMJD1C | jumonji domain containing 1C | -0.0224073 |
| ETV6 | ets variant 6 | -0.0220841 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0217702 |
| DTNA | dystrobrevin, alpha | -0.0216434 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0216432 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0215313 |
| R3HDM2 | R3H domain containing 2 | -0.0215221 |
| COMMD10 | COMM domain containing 10 | -0.0214669 |
| MYPN | myopalladin | -0.0214496 |
| EXOC4 | exocyst complex component 4 | -0.0213873 |
| CEP112 | centrosomal protein 112kDa | -0.0211725 |
| NAV3 | neuron navigator 3 | -0.0206055 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0204554 |
| DENND5A | DENN/MADD domain containing 5A | -0.0202954 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0199328 |
| RAD51B | RAD51 paralog B | -0.0199236 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0197836 |
| TBCA | tubulin folding cofactor A | -0.0197829 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0196863 |
| PRKCE | protein kinase C, epsilon | -0.0196759 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0193925 |
| GNAS | GNAS complex locus | -0.0192356 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0191694 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0190878 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0188267 |
| AEBP2 | AE binding protein 2 | -0.0186793 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0186582 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0185923 |
| E2F3 | E2F transcription factor 3 | -0.0185879 |
| RNF213 | ring finger protein 213 | -0.018429 |
| RPS3 | ribosomal protein S3 | -0.0184103 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0183543 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0183307 |
| RSU1 | Ras suppressor protein 1 | -0.0182247 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0180951 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0180643 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0180494 |
