| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0717604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0656058 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0458489 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0386519 |
| SEC24D | SEC24 family member D | 0.0346044 |
| INTS6 | integrator complex subunit 6 | 0.03376 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0310845 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0304502 |
| CANX | calnexin | 0.0271989 |
| COG6 | component of oligomeric golgi complex 6 | 0.0269052 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0267872 |
| FNIP1 | folliculin interacting protein 1 | 0.0265522 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0240664 |
| GOLGA4 | golgin A4 | 0.0231998 |
| AHI1 | Abelson helper integration site 1 | 0.0227727 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0224828 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0223608 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0214687 |
| IFNGR1 | interferon gamma receptor 1 | 0.0207573 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0200319 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0197759 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0197233 |
| ARRDC3 | arrestin domain containing 3 | 0.0195974 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0195271 |
| SUCO | SUN domain containing ossification factor | 0.0186356 |
| SSR1 | signal sequence receptor, alpha | 0.0174145 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.017199 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0171598 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0171578 |
| HBS1L | HBS1-like translational GTPase | 0.0168123 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0167792 |
| USP3 | ubiquitin specific peptidase 3 | 0.0166922 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.016118 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0159317 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0157813 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0157249 |
| PLSCR2 | phospholipid scramblase 2 | 0.0156445 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0155962 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0154298 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0153932 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0150772 |
| TSC22D2 | TSC22 domain family, member 2 | 0.014995 |
| HELZ | helicase with zinc finger | 0.0149401 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0147112 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0146519 |
| HDLBP | high density lipoprotein binding protein | 0.0144378 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0143462 |
| TMEM263 | transmembrane protein 263 | 0.0142809 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0141951 |
| UBL3 | ubiquitin-like 3 | 0.0139471 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0136719 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0135467 |
| MORF4L2 | mortality factor 4 like 2 | 0.0134089 |
| HYOU1 | hypoxia up-regulated 1 | 0.0133123 |
| KIZ | kizuna centrosomal protein | 0.0132321 |
| SCFD1 | sec1 family domain containing 1 | 0.0130529 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0128006 |
| SEC24A | SEC24 family member A | 0.0126912 |
| PGM3 | phosphoglucomutase 3 | 0.0125908 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0125004 |
| PRELID2 | PRELI domain containing 2 | 0.0124473 |
| WDR26 | WD repeat domain 26 | 0.0124466 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0122456 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0122151 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0121749 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.012159 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0121239 |
| TMEM39A | transmembrane protein 39A | 0.0121212 |
| DIAPH3 | diaphanous-related formin 3 | 0.0120732 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0119108 |
| FAT1 | FAT atypical cadherin 1 | 0.011909 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0118857 |
| KLHL24 | kelch-like family member 24 | 0.0118778 |
| SRP54 | signal recognition particle 54kDa | 0.0117289 |
| ZNF451 | zinc finger protein 451 | 0.0115952 |
| LNX2 | ligand of numb-protein X 2 | 0.0115437 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0115007 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0114918 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0114704 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0114456 |
| SMAD3 | SMAD family member 3 | 0.0114413 |
| CEP350 | centrosomal protein 350kDa | 0.0113312 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0113196 |
| TXNDC11 | thioredoxin domain containing 11 | 0.0113164 |
| CALU | calumenin | 0.0113039 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0112371 |
| PTEN | phosphatase and tensin homolog | 0.0112206 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.011204 |
| COPA | coatomer protein complex, subunit alpha | 0.0110488 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0109162 |
| FANCI | Fanconi anemia, complementation group I | 0.0109157 |
| DMXL2 | Dmx-like 2 | 0.0108082 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0106677 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0106632 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0106122 |
| RNF149 | ring finger protein 149 | 0.0105992 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0105906 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0105623 |
| SFXN1 | sideroflexin 1 | 0.0105272 |
| RBM33 | RNA binding motif protein 33 | 0.010517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.177486 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.166226 |
| LYZ | lysozyme | -0.113571 |
| LCN2 | lipocalin 2 | -0.10896 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.105581 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0994721 |
| HLA-B | major histocompatibility complex, class I, B | -0.0951278 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0891895 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0852689 |
| MX2 | MX dynamin-like GTPase 2 | -0.0849711 |
| PTMA | prothymosin, alpha | -0.0848912 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0818179 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0724899 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0721534 |
| RNF213 | ring finger protein 213 | -0.0718107 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0711186 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0704375 |
| TMC5 | transmembrane channel-like 5 | -0.0701438 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0696047 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0688128 |
| RIGI | RNA sensor RIG-I | -0.0683021 |
| MX1 | MX dynamin-like GTPase 1 | -0.0681851 |
| ITGA6 | integrin, alpha 6 | -0.0667833 |
| SP100 | SP100 nuclear antigen | -0.0630204 |
| XAF1 | XIAP associated factor 1 | -0.062174 |
| TMSB10 | thymosin beta 10 | -0.0608595 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0607733 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0604442 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0593839 |
| SPATA13 | spermatogenesis associated 13 | -0.0592753 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0573396 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0547304 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0538571 |
| EPHB2 | EPH receptor B2 | -0.0538333 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0507092 |
| PLSCR1 | phospholipid scramblase 1 | -0.0482906 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0477059 |
| MT2A | metallothionein 2A | -0.0472425 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0469747 |
| PKM | pyruvate kinase, muscle | -0.0456093 |
| SSH2 | slingshot protein phosphatase 2 | -0.0453173 |
| NPSR1 | neuropeptide S receptor 1 | -0.0452759 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0451896 |
| EGR1 | early growth response 1 | -0.0450078 |
| JUN | jun proto-oncogene | -0.043983 |
| RPL35A | ribosomal protein L35a | -0.0432862 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0424959 |
| PRKCA | protein kinase C, alpha | -0.0424366 |
| ATP11A | ATPase, class VI, type 11A | -0.0422966 |
| NCKAP5 | NCK-associated protein 5 | -0.0416372 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0411492 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0406833 |
| ERBIN | erbb2 interacting protein | -0.0405267 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0399302 |
| FTL | ferritin, light polypeptide | -0.0398391 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0390539 |
| H1-0 | H1.0 linker histone | -0.0382601 |
| PTGR1 | prostaglandin reductase 1 | -0.0366889 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0366505 |
| HLA-A | major histocompatibility complex, class I, A | -0.0361473 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0354754 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0354456 |
| ETV6 | ets variant 6 | -0.0354129 |
| RPL23 | ribosomal protein L23 | -0.0351001 |
| PMP22 | peripheral myelin protein 22 | -0.0347792 |
| RAD51B | RAD51 paralog B | -0.034518 |
| KRT19 | keratin 19, type I | -0.0342966 |
| MSI2 | musashi RNA-binding protein 2 | -0.0339174 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0336497 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0336189 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0332662 |
| PERP | PERP, TP53 apoptosis effector | -0.0332577 |
| SQSTM1 | sequestosome 1 | -0.0329853 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0327741 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0324297 |
| RBM47 | RNA binding motif protein 47 | -0.0321392 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.031681 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0311624 |
| TRIM56 | tripartite motif containing 56 | -0.0310288 |
| RPS19 | ribosomal protein S19 | -0.0309267 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0308717 |
| MAP7 | microtubule-associated protein 7 | -0.0308397 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307319 |
| HLA-C | major histocompatibility complex, class I, C | -0.0306713 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0305338 |
| MUC20 | mucin 20, cell surface associated | -0.0305052 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0299458 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0296855 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0294433 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0294239 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0290795 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.029004 |
| PGK1 | phosphoglycerate kinase 1 | -0.0289075 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0288401 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0285575 |
| MECOM | MDS1 and EVI1 complex locus | -0.0284781 |
| ASPH | aspartate beta-hydroxylase | -0.0284551 |
| ATP10B | ATPase, class V, type 10B | -0.0284323 |
| CST3 | cystatin C | -0.0283279 |
| MUC13 | mucin 13, cell surface associated | -0.0282188 |