| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0971499 |
| B2M | beta-2-microglobulin | 0.082966 |
| ENO1 | enolase 1, (alpha) | 0.0766824 |
| CLU | clusterin | 0.0720323 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0704477 |
| PTMA | prothymosin, alpha | 0.0673808 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0643558 |
| GOLGA4 | golgin A4 | 0.0605989 |
| PGK1 | phosphoglycerate kinase 1 | 0.0604526 |
| MYOF | myoferlin | 0.0578451 |
| CANX | calnexin | 0.0546878 |
| ANXA1 | annexin A1 | 0.0544977 |
| KRT17 | keratin 17, type I | 0.0540684 |
| SQLE | squalene epoxidase | 0.0515421 |
| RBM39 | RNA binding motif protein 39 | 0.0505642 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0485568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0478813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473828 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0463804 |
| MEF2A | myocyte enhancer factor 2A | 0.0459256 |
| DSTN | destrin (actin depolymerizing factor) | 0.0457545 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0454068 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0415557 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0415047 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0401676 |
| FLNB | filamin B, beta | 0.038568 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0382536 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.037798 |
| POTEF | POTE ankyrin domain family, member F | 0.0372961 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0367466 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0351654 |
| S100A10 | S100 calcium binding protein A10 | 0.0345176 |
| EZR | ezrin | 0.0344091 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0338443 |
| ARRDC3 | arrestin domain containing 3 | 0.033631 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0335348 |
| OGA | O-GlcNAcase | 0.0332827 |
| CALU | calumenin | 0.0329799 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0329279 |
| YBX1 | Y box binding protein 1 | 0.0327759 |
| LDHA | lactate dehydrogenase A | 0.0325717 |
| ANLN | anillin, actin binding protein | 0.0325534 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0324018 |
| SUCO | SUN domain containing ossification factor | 0.0321521 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0319835 |
| KRT6A | keratin 6A, type II | 0.03153 |
| MATR3 | matrin 3 | 0.0313448 |
| MORF4L2 | mortality factor 4 like 2 | 0.0309257 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0307419 |
| COG5 | component of oligomeric golgi complex 5 | 0.0304934 |
| NUP58 | nucleoporin 58 | 0.0297344 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0294146 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0290518 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0285609 |
| MT2A | metallothionein 2A | 0.0282753 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282576 |
| HELZ | helicase with zinc finger | 0.0282301 |
| RLF | rearranged L-myc fusion | 0.0281679 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0276962 |
| RPS8 | ribosomal protein S8 | 0.0276834 |
| TMSB10 | thymosin beta 10 | 0.0276574 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0276408 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0275095 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.027389 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.027225 |
| SRP54 | signal recognition particle 54kDa | 0.0271699 |
| RNF145 | ring finger protein 145 | 0.0268934 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0268363 |
| QKI | QKI, KH domain containing, RNA binding | 0.0266624 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0265182 |
| SERINC3 | serine incorporator 3 | 0.0263103 |
| TFG | TRK-fused gene | 0.0262363 |
| RPS13 | ribosomal protein S13 | 0.0261119 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0260953 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0258571 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0257819 |
| RPS6 | ribosomal protein S6 | 0.0257804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0255159 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0254797 |
| SFTPA2 | surfactant protein A2 | 0.0254657 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0250511 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0249401 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0247822 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0244188 |
| COPA | coatomer protein complex, subunit alpha | 0.0241777 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0241369 |
| RPLP1 | ribosomal protein, large, P1 | 0.0241084 |
| FTL | ferritin, light polypeptide | 0.0239506 |
| ITGA6 | integrin, alpha 6 | 0.0238654 |
| PCBP2 | poly(rC) binding protein 2 | 0.0238432 |
| NDRG1 | N-myc downstream regulated 1 | 0.0238267 |
| S100A6 | S100 calcium binding protein A6 | 0.0238198 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0237142 |
| RIOK3 | RIO kinase 3 | 0.0235131 |
| CD99 | CD99 molecule | 0.0234937 |
| RPLP0 | ribosomal protein, large, P0 | 0.0233674 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0233309 |
| PKM | pyruvate kinase, muscle | 0.0233188 |
| TPM3 | tropomyosin 3 | 0.0232901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.197306 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.085728 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0836216 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0742104 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0673734 |
| LMO7 | LIM domain 7 | -0.0672209 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0652258 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0631004 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0592928 |
| RIGI | RNA sensor RIG-I | -0.0497607 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0494686 |
| HMGA2 | high mobility group AT-hook 2 | -0.0427097 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0409639 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0409317 |
| INTS6 | integrator complex subunit 6 | -0.0398561 |
| RAD51B | RAD51 paralog B | -0.0372374 |
| RASAL2 | RAS protein activator like 2 | -0.0364163 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0343476 |
| PRSS23 | protease, serine, 23 | -0.0333993 |
| MTSS1 | metastasis suppressor 1 | -0.0326354 |
| CDK6 | cyclin-dependent kinase 6 | -0.0314153 |
| SMYD3 | SET and MYND domain containing 3 | -0.0313038 |
| MECOM | MDS1 and EVI1 complex locus | -0.031258 |
| LAMC2 | laminin, gamma 2 | -0.0310831 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0298231 |
| PALLD | palladin, cytoskeletal associated protein | -0.0291035 |
| FN1 | fibronectin 1 | -0.0290984 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0282925 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0280626 |
| EFNA5 | ephrin-A5 | -0.0277953 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0276457 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0276189 |
| DOK5 | docking protein 5 | -0.0275973 |
| SULF1 | sulfatase 1 | -0.0271733 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0271584 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0270546 |
| RAI14 | retinoic acid induced 14 | -0.0270289 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0269532 |
| OSMR | oncostatin M receptor | -0.0265344 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0263141 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0242836 |
| TENM4 | teneurin transmembrane protein 4 | -0.0241502 |
| MTAP | methylthioadenosine phosphorylase | -0.0239318 |
| VCL | vinculin | -0.0237868 |
| PLXNA2 | plexin A2 | -0.0235303 |
| AMOTL1 | angiomotin like 1 | -0.0234241 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0233695 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.023297 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0229507 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0227086 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0223635 |
| C4BPB | complement component 4 binding protein, beta | -0.022324 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0222192 |
| AOPEP | aminopeptidase O (putative) | -0.0220351 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0217618 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0217228 |
| KIAA1671 | KIAA1671 | -0.0214478 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0213773 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0211004 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0206353 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0204007 |
| ACTN4 | actinin, alpha 4 | -0.0200781 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0198464 |
| AHNAK | AHNAK nucleoprotein | -0.0198367 |
| SULF2 | sulfatase 2 | -0.0195058 |
| PODXL | podocalyxin-like | -0.0192544 |
| EXOC4 | exocyst complex component 4 | -0.0192139 |
| RNF217 | ring finger protein 217 | -0.0191505 |
| DST | dystonin | -0.0190489 |
| KIAA0040 | KIAA0040 | -0.018828 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0186203 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0185539 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0184836 |
| SVIL | supervillin | -0.0183625 |
| PLEC | plectin | -0.0181372 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0179838 |
| HDAC9 | histone deacetylase 9 | -0.0179148 |
| ACTN1 | actinin, alpha 1 | -0.0178668 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.017844 |
| TNS3 | tensin 3 | -0.0175855 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0175357 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0174974 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.017292 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.017124 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0169142 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0169059 |
| NAV2 | neuron navigator 2 | -0.0167723 |
| EGFR | epidermal growth factor receptor | -0.0167482 |
| FRMD4B | FERM domain containing 4B | -0.0166436 |
| UTRN | utrophin | -0.0165838 |
| PRELID2 | PRELI domain containing 2 | -0.0160924 |
| LUZP1 | leucine zipper protein 1 | -0.0160816 |
| PLS3 | plastin 3 | -0.0159985 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0159052 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0158837 |
| CRACDL | CRACD like | -0.0157419 |
| FOXO1 | forkhead box O1 | -0.0156989 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0156292 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0154614 |
| LAMA4 | laminin, alpha 4 | -0.0154503 |