| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hesperidin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.12625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.07346 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0686774 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0658289 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0639059 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0540348 |
| RNF145 | ring finger protein 145 | 0.0477459 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0473178 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0472026 |
| EREG | epiregulin | 0.0458139 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0405322 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390022 |
| ENO1 | enolase 1, (alpha) | 0.0388198 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0380533 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0378476 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0373404 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0362745 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342556 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0341677 |
| AREG | amphiregulin | 0.0335151 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0335073 |
| FTL | ferritin, light polypeptide | 0.0331081 |
| MED13L | mediator complex subunit 13-like | 0.0321434 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0315751 |
| RPS23 | ribosomal protein S23 | 0.0313079 |
| B2M | beta-2-microglobulin | 0.0308831 |
| TXNIP | thioredoxin interacting protein | 0.0304223 |
| RPLP0 | ribosomal protein, large, P0 | 0.0293444 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0289445 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.028923 |
| XPO1 | exportin 1 | 0.0287208 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286554 |
| NUP58 | nucleoporin 58 | 0.0281295 |
| YBX1 | Y box binding protein 1 | 0.0280301 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0279891 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0279357 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0277209 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0267675 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0262169 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0261192 |
| KIF5B | kinesin family member 5B | 0.0258602 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0257448 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0256319 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0254599 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0254219 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0249516 |
| RPL23 | ribosomal protein L23 | 0.0245964 |
| MATR3 | matrin 3 | 0.0242951 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0240278 |
| ZNF292 | zinc finger protein 292 | 0.0237342 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0230401 |
| PTEN | phosphatase and tensin homolog | 0.0227362 |
| RPS25 | ribosomal protein S25 | 0.022708 |
| TPM3 | tropomyosin 3 | 0.02269 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0226507 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0223032 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0222665 |
| POTEF | POTE ankyrin domain family, member F | 0.0221775 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220053 |
| YTHDC1 | YTH domain containing 1 | 0.0218258 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0218 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0217826 |
| VMP1 | vacuole membrane protein 1 | 0.021732 |
| RBM39 | RNA binding motif protein 39 | 0.0216013 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0214746 |
| SET | SET nuclear proto-oncogene | 0.0213628 |
| WDR43 | WD repeat domain 43 | 0.0212399 |
| NCKAP1 | NCK-associated protein 1 | 0.0211623 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0210625 |
| CCNL1 | cyclin L1 | 0.0206614 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.02063 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0206118 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203959 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0203899 |
| RAB1A | RAB1A, member RAS oncogene family | 0.020387 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201783 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0201563 |
| CUL3 | cullin 3 | 0.0200547 |
| FAM13A | family with sequence similarity 13, member A | 0.0200184 |
| TFG | TRK-fused gene | 0.0200181 |
| ANXA1 | annexin A1 | 0.0199458 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0196616 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0195693 |
| ZNF148 | zinc finger protein 148 | 0.0193337 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0191593 |
| HELZ | helicase with zinc finger | 0.0190532 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0189175 |
| CCNY | cyclin Y | 0.0188993 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0187999 |
| FRYL | FRY-like | 0.0187747 |
| GLG1 | golgi glycoprotein 1 | 0.0182216 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0182156 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0181396 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0180169 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.018016 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0179173 |
| ATF4 | activating transcription factor 4 | 0.0179123 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0178541 |
| SLMAP | sarcolemma associated protein | 0.0176922 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0176785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.0704468 |
| ONECUT3 | one cut homeobox 3 | -0.056343 |
| TMSB10 | thymosin beta 10 | -0.0543833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0540591 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0474028 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0412561 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0396976 |
| H1-0 | H1.0 linker histone | -0.0359845 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0340999 |
| ANXA2 | annexin A2 | -0.0327293 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0316245 |
| PRELID2 | PRELI domain containing 2 | -0.0277792 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0277426 |
| PRSS3 | protease, serine, 3 | -0.0266865 |
| POF1B | premature ovarian failure, 1B | -0.026419 |
| CADPS | Ca++-dependent secretion activator | -0.0263421 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0250663 |
| NDRG1 | N-myc downstream regulated 1 | -0.0231559 |
| RRBP1 | ribosome binding protein 1 | -0.0227011 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0220572 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0216146 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0212129 |
| VCL | vinculin | -0.0206697 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0203669 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0198802 |
| FERMT1 | fermitin family member 1 | -0.0198548 |
| TNS4 | tensin 4 | -0.0197823 |
| FLNB | filamin B, beta | -0.0193552 |
| TRIM2 | tripartite motif containing 2 | -0.0186652 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0183113 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0180355 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0179835 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0179291 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0177983 |
| LAMB3 | laminin, beta 3 | -0.017737 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0176557 |
| MECOM | MDS1 and EVI1 complex locus | -0.0173992 |
| MYO1D | myosin ID | -0.0172425 |
| ACTN4 | actinin, alpha 4 | -0.0172241 |
| MUC17 | mucin 17, cell surface associated | -0.0171445 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0170442 |
| ITGB4 | integrin, beta 4 | -0.0167113 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0163579 |
| AHNAK | AHNAK nucleoprotein | -0.0160428 |
| MT2A | metallothionein 2A | -0.0159996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0158931 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0154271 |
| PLEC | plectin | -0.0152352 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0151523 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0149745 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0148759 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0148138 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0148006 |
| EFNB2 | ephrin-B2 | -0.0145712 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0145685 |
| ATXN1 | ataxin 1 | -0.0143507 |
| CD44 | CD44 molecule (Indian blood group) | -0.0143359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0142805 |
| KIAA1217 | KIAA1217 | -0.0141465 |
| NFIA | nuclear factor I/A | -0.0140663 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0140394 |
| LAMA4 | laminin, alpha 4 | -0.0140261 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0139818 |
| HDLBP | high density lipoprotein binding protein | -0.0138899 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0137712 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0135549 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0135364 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.0135309 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0134562 |
| MYO1E | myosin IE | -0.0133663 |
| NRN1 | neuritin 1 | -0.0130936 |
| CEP95 | centrosomal protein 95kDa | -0.012947 |
| RESF1 | retroelement silencing factor 1 | -0.0129262 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0129165 |
| MTAP | methylthioadenosine phosphorylase | -0.0128132 |
| FOXP1 | forkhead box P1 | -0.0127686 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0125607 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0125523 |
| CAB39 | calcium binding protein 39 | -0.0125354 |
| SH3D19 | SH3 domain containing 19 | -0.0125278 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0123833 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.012334 |
| CCDC146 | coiled-coil domain containing 146 | -0.0122516 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0122293 |
| AGR2 | anterior gradient 2 | -0.0120794 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0120119 |
| KLF6 | Kruppel-like factor 6 | -0.0119287 |
| RNF217 | ring finger protein 217 | -0.0117342 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0117302 |
| GOLGB1 | golgin B1 | -0.0116995 |
| GPHN | gephyrin | -0.0116245 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.011614 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0116086 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0115042 |
| ABHD17C | abhydrolase domain containing 17C | -0.0114771 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0114681 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0113627 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0113231 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.011271 |
| MT1X | metallothionein 1X | -0.0112502 |
