| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0882835 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0785554 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0690012 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0533696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513786 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0494427 |
| TMSB4X | thymosin beta 4, X-linked | 0.0416237 |
| TMEM123 | transmembrane protein 123 | 0.0404447 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0353304 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.033236 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0319553 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0302392 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0284479 |
| MATR3 | matrin 3 | 0.0279154 |
| EFNA5 | ephrin-A5 | 0.0277827 |
| POTEF | POTE ankyrin domain family, member F | 0.0264051 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0262695 |
| ENO1 | enolase 1, (alpha) | 0.0257992 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0250214 |
| NUP58 | nucleoporin 58 | 0.0242875 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0240797 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0238445 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0232408 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231684 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0223688 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0221768 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0221696 |
| QKI | QKI, KH domain containing, RNA binding | 0.0220627 |
| EPHA4 | EPH receptor A4 | 0.0217766 |
| PLIN2 | perilipin 2 | 0.0215367 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0213637 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0212507 |
| YBX1 | Y box binding protein 1 | 0.0212499 |
| ECT2 | epithelial cell transforming 2 | 0.0211196 |
| PLK2 | polo-like kinase 2 | 0.020959 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0207883 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0207652 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0204879 |
| CALR | calreticulin | 0.0204224 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0199872 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0199081 |
| TOP1 | topoisomerase (DNA) I | 0.0198838 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0198014 |
| ANXA2 | annexin A2 | 0.0197803 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0197223 |
| MAP4 | microtubule-associated protein 4 | 0.0195322 |
| PGK1 | phosphoglycerate kinase 1 | 0.0193624 |
| OLA1 | Obg-like ATPase 1 | 0.0193262 |
| ANXA1 | annexin A1 | 0.0192376 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0190216 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0189002 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0187876 |
| AHNAK | AHNAK nucleoprotein | 0.0187632 |
| MYOF | myoferlin | 0.0185528 |
| CANX | calnexin | 0.0183483 |
| HELZ | helicase with zinc finger | 0.0176902 |
| FBXO42 | F-box protein 42 | 0.0174782 |
| CFAP299 | cilia and flagella associated protein 299 | 0.017335 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0173264 |
| TFG | TRK-fused gene | 0.0173022 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0172169 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.0171727 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0171528 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0170958 |
| SET | SET nuclear proto-oncogene | 0.0168896 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0168618 |
| WDR45B | WD repeat domain 45B | 0.0165561 |
| NPR2 | natriuretic peptide receptor 2 | 0.0164868 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0163883 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0163341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0163335 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0161716 |
| RLF | rearranged L-myc fusion | 0.0161312 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0160627 |
| CCNL1 | cyclin L1 | 0.0160318 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0159981 |
| TNPO1 | transportin 1 | 0.0158107 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0153726 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0152889 |
| CRY1 | cryptochrome circadian clock 1 | 0.0152654 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0151935 |
| IPO7 | importin 7 | 0.0150232 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0150005 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0149821 |
| TFRC | transferrin receptor | 0.014946 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0148003 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0147281 |
| MTF2 | metal response element binding transcription factor 2 | 0.0146199 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0144855 |
| WDR43 | WD repeat domain 43 | 0.0144426 |
| HBS1L | HBS1-like translational GTPase | 0.0143813 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0143756 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0143349 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.014329 |
| RNF145 | ring finger protein 145 | 0.0142334 |
| RPLP0 | ribosomal protein, large, P0 | 0.0140032 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0139385 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0137795 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0136656 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0136625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.252033 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.127308 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.10646 |
| TP63 | tumor protein p63 | -0.0807099 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0748087 |
| TMSB10 | thymosin beta 10 | -0.0629337 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0601609 |
| CAPRIN2 | caprin family member 2 | -0.0555246 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0535847 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0482379 |
| MT1X | metallothionein 1X | -0.0474665 |
| RPS6 | ribosomal protein S6 | -0.0465597 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0457206 |
| USP34 | ubiquitin specific peptidase 34 | -0.0437445 |
| MT1E | metallothionein 1E | -0.0429535 |
| TXNRD1 | thioredoxin reductase 1 | -0.0415872 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0413567 |
| FMNL2 | formin-like 2 | -0.0402829 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0400191 |
| RPS19 | ribosomal protein S19 | -0.0377008 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0370286 |
| FTL | ferritin, light polypeptide | -0.036425 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0363242 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0351714 |
| EMP1 | epithelial membrane protein 1 | -0.035151 |
| RPS2 | ribosomal protein S2 | -0.0335408 |
| ANGPTL4 | angiopoietin-like 4 | -0.0334007 |
| PTMA | prothymosin, alpha | -0.032928 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0324313 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0323595 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.031112 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0300785 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0298745 |
| RPL36 | ribosomal protein L36 | -0.0296415 |
| CMIP | c-Maf inducing protein | -0.0294719 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293124 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0291835 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0289015 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0286846 |
| PDE10A | phosphodiesterase 10A | -0.028382 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0275235 |
| RPL26 | ribosomal protein L26 | -0.0274217 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0272908 |
| RPL35A | ribosomal protein L35a | -0.0271746 |
| RPS3 | ribosomal protein S3 | -0.0268551 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0268441 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0266703 |
| RPL38 | ribosomal protein L38 | -0.0261698 |
| SQSTM1 | sequestosome 1 | -0.0261366 |
| RUNX1 | runt-related transcription factor 1 | -0.0257324 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0255465 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0254459 |
| CDCP1 | CUB domain containing protein 1 | -0.0249389 |
| LOXL2 | lysyl oxidase-like 2 | -0.024823 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0246068 |
| RPL37A | ribosomal protein L37a | -0.0245919 |
| HPCAL1 | hippocalcin-like 1 | -0.0244799 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0241483 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0239727 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0238688 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0236774 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0235546 |
| MKI67 | marker of proliferation Ki-67 | -0.023148 |
| EZR | ezrin | -0.0229897 |
| RPL18 | ribosomal protein L18 | -0.0225921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0225602 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0222065 |
| RPL19 | ribosomal protein L19 | -0.0220922 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0213171 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0209669 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0209485 |
| PYGL | phosphorylase, glycogen, liver | -0.0209137 |
| SP100 | SP100 nuclear antigen | -0.0208275 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0208154 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0206797 |
| CD44 | CD44 molecule (Indian blood group) | -0.0203573 |
| YBX3 | Y box binding protein 3 | -0.0203522 |
| PRDX1 | peroxiredoxin 1 | -0.0200463 |
| RAD51B | RAD51 paralog B | -0.0200435 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0198434 |
| FERMT1 | fermitin family member 1 | -0.0197837 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0196253 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0195705 |
| SMYD3 | SET and MYND domain containing 3 | -0.0187039 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0185768 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0184898 |
| RPLP2 | ribosomal protein, large, P2 | -0.0183573 |
| RPS10 | ribosomal protein S10 | -0.0180478 |
| VCL | vinculin | -0.0180423 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0180127 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0179365 |
| RPL12 | ribosomal protein L12 | -0.0179168 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0179051 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0176515 |
| NEK10 | NIMA-related kinase 10 | -0.017622 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0174038 |
| PRELID2 | PRELI domain containing 2 | -0.0172756 |
| S100A6 | S100 calcium binding protein A6 | -0.0172309 |
| CLTC | clathrin, heavy chain (Hc) | -0.017219 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.01715 |
