| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.107903 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0660719 |
| RNF145 | ring finger protein 145 | 0.063841 |
| TOP1 | topoisomerase (DNA) I | 0.0592385 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0581925 |
| UVRAG | UV radiation resistance associated | 0.0579205 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0532802 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0525087 |
| FTL | ferritin, light polypeptide | 0.0425117 |
| ARRDC3 | arrestin domain containing 3 | 0.0400466 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0397312 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0387092 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0386129 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0356993 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0356045 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0350484 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0345989 |
| TPD52 | tumor protein D52 | 0.033905 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.033852 |
| NCKAP1 | NCK-associated protein 1 | 0.0322677 |
| SLMAP | sarcolemma associated protein | 0.0318125 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0316784 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0308572 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0306581 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0303035 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0295384 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0294884 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0294084 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0287766 |
| PGK1 | phosphoglycerate kinase 1 | 0.0279697 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0278918 |
| HBP1 | HMG-box transcription factor 1 | 0.0277142 |
| RPLP0 | ribosomal protein, large, P0 | 0.0276389 |
| LMO7 | LIM domain 7 | 0.0275081 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0274846 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0266732 |
| NUP58 | nucleoporin 58 | 0.026584 |
| WASF2 | WAS protein family, member 2 | 0.0264532 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0261297 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0257246 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256288 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0256006 |
| PTMA | prothymosin, alpha | 0.0255218 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0250037 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0249206 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0244135 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0237997 |
| ATP13A3 | ATPase type 13A3 | 0.0236306 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0236281 |
| ANXA2 | annexin A2 | 0.0234132 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0226184 |
| ENO1 | enolase 1, (alpha) | 0.0222502 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0220611 |
| HELZ | helicase with zinc finger | 0.0218015 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0215704 |
| ANXA1 | annexin A1 | 0.0215061 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214202 |
| FAM13A | family with sequence similarity 13, member A | 0.0212314 |
| MYOF | myoferlin | 0.0212206 |
| TKT | transketolase | 0.0211641 |
| TFG | TRK-fused gene | 0.0210091 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0209145 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0204307 |
| USP3 | ubiquitin specific peptidase 3 | 0.019931 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0199171 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0198844 |
| ANXA5 | annexin A5 | 0.019532 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0194531 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0192578 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0191561 |
| WDR45B | WD repeat domain 45B | 0.0191252 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0189569 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0188022 |
| RPS4X | ribosomal protein S4, X-linked | 0.0187957 |
| TXNRD1 | thioredoxin reductase 1 | 0.0187485 |
| TMEM165 | transmembrane protein 165 | 0.0187423 |
| MATR3 | matrin 3 | 0.0186738 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0185438 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0184564 |
| TMSB10 | thymosin beta 10 | 0.018277 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0181658 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0181434 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0179274 |
| ECT2 | epithelial cell transforming 2 | 0.0174618 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0170334 |
| RAB21 | RAB21, member RAS oncogene family | 0.0166164 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0166054 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0165735 |
| USP12 | ubiquitin specific peptidase 12 | 0.0163514 |
| PDE8A | phosphodiesterase 8A | 0.0163182 |
| ATG14 | autophagy related 14 | 0.0162254 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0161101 |
| TMEM41B | transmembrane protein 41B | 0.015973 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0158817 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0158705 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0158562 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0157656 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.015761 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0156382 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | 0.0155831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.114407 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0563059 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0543502 |
| LAMC2 | laminin, gamma 2 | -0.0521919 |
| MT2A | metallothionein 2A | -0.0520387 |
| OSMR | oncostatin M receptor | -0.0469146 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0439487 |
| NDRG1 | N-myc downstream regulated 1 | -0.0389685 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0385861 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0370551 |
| MCL1 | myeloid cell leukemia 1 | -0.0340141 |
| EFNA5 | ephrin-A5 | -0.0338797 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0325052 |
| LAMA4 | laminin, alpha 4 | -0.0320133 |
| MKI67 | marker of proliferation Ki-67 | -0.0309648 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0293813 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0289652 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0285062 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0283795 |
| SLTM | SAFB-like, transcription modulator | -0.0279289 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0278929 |
| STC1 | stanniocalcin 1 | -0.0275037 |
| GOLGB1 | golgin B1 | -0.0273463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0272114 |
| ZNF638 | zinc finger protein 638 | -0.0270767 |
| DSCAM | Down syndrome cell adhesion molecule | -0.026778 |
| BPTF | bromodomain PHD finger transcription factor | -0.0258692 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0255194 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0245892 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0245719 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245001 |
| CES1 | carboxylesterase 1 | -0.0239078 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0234283 |
| NABP1 | nucleic acid binding protein 1 | -0.0227059 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0223285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0215356 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0209741 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0203019 |
| RTN4 | reticulon 4 | -0.019435 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0192246 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0192095 |
| RAD51B | RAD51 paralog B | -0.0189203 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0187448 |
| GPATCH2L | G patch domain containing 2-like | -0.0186463 |
| VCL | vinculin | -0.0181102 |
| FOXP1 | forkhead box P1 | -0.0179909 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0178483 |
| SUMF1 | sulfatase modifying factor 1 | -0.0172247 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0169962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0168614 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0167998 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0167939 |
| ATP11A | ATPase, class VI, type 11A | -0.0166559 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0166236 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0166017 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0164472 |
| EGR1 | early growth response 1 | -0.0161975 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0161469 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0159933 |
| USP34 | ubiquitin specific peptidase 34 | -0.0158607 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0157763 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0157664 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0157617 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0156659 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0154884 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.015484 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0153255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0152162 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0151887 |
| TRIM56 | tripartite motif containing 56 | -0.0150236 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.014957 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.014818 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.014776 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0145971 |
| TMEM45B | transmembrane protein 45B | -0.0144567 |
| WDR26 | WD repeat domain 26 | -0.0144567 |
| SEPTIN10 | septin 10 | -0.014225 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0140983 |
| NF1 | neurofibromin 1 | -0.0139435 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0139167 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0139101 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0138978 |
| MYO1E | myosin IE | -0.0138878 |
| GOLGA4 | golgin A4 | -0.0138528 |
| PRELID2 | PRELI domain containing 2 | -0.0137861 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0137173 |
| FNIP1 | folliculin interacting protein 1 | -0.0136893 |
| CUL4A | cullin 4A | -0.013529 |
| CDCP1 | CUB domain containing protein 1 | -0.0133745 |
| KIAA1328 | KIAA1328 | -0.0133198 |
| H1-0 | H1.0 linker histone | -0.0132285 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0131939 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0129128 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.012885 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0128843 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0128533 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0128312 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0127976 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0127371 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.0127352 |
