| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hesperidin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.142801 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.135547 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.131957 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0844008 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.077477 |
| ATP13A3 | ATPase type 13A3 | 0.0774468 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0742172 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0736385 |
| USP3 | ubiquitin specific peptidase 3 | 0.0711187 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0642748 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0579274 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0562719 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0548661 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0547597 |
| FAM13A | family with sequence similarity 13, member A | 0.0530862 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.052317 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0517788 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0511573 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0503664 |
| RNF145 | ring finger protein 145 | 0.0489024 |
| QKI | QKI, KH domain containing, RNA binding | 0.0485916 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0485349 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0483097 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0476954 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0469977 |
| YBX1 | Y box binding protein 1 | 0.0462037 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.046067 |
| SPAG9 | sperm associated antigen 9 | 0.046024 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0460144 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0457675 |
| ENO1 | enolase 1, (alpha) | 0.0454349 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0452023 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.045025 |
| RIOK3 | RIO kinase 3 | 0.0444298 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.044428 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0435466 |
| FTL | ferritin, light polypeptide | 0.0434399 |
| RPLP0 | ribosomal protein, large, P0 | 0.0416461 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.040744 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0405494 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0391253 |
| PARD3 | par-3 family cell polarity regulator | 0.0389743 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.038821 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0386345 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0379772 |
| ANXA1 | annexin A1 | 0.0378049 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0376484 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0374472 |
| HELZ | helicase with zinc finger | 0.0366147 |
| MEF2A | myocyte enhancer factor 2A | 0.036046 |
| RLF | rearranged L-myc fusion | 0.0355578 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0347468 |
| NUP58 | nucleoporin 58 | 0.0346628 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0338963 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0337809 |
| RBM39 | RNA binding motif protein 39 | 0.0330537 |
| GOLGA4 | golgin A4 | 0.0330284 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0328936 |
| CDC73 | cell division cycle 73 | 0.032672 |
| RAB6A | RAB6A, member RAS oncogene family | 0.032305 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0318171 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0317281 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0314307 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0308602 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0305389 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0305338 |
| XPO1 | exportin 1 | 0.0304138 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0304121 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0303609 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0303222 |
| MATR3 | matrin 3 | 0.0301602 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295747 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0294183 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0294071 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0293088 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0292086 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0289695 |
| CCNY | cyclin Y | 0.028908 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0288526 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0287705 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0285803 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0285216 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0285194 |
| YME1L1 | YME1-like 1 ATPase | 0.0284027 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0283744 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0279047 |
| PKM | pyruvate kinase, muscle | 0.0277518 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0277498 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0275142 |
| KIF5B | kinesin family member 5B | 0.027431 |
| OLA1 | Obg-like ATPase 1 | 0.0272694 |
| USP15 | ubiquitin specific peptidase 15 | 0.0269799 |
| ZNF207 | zinc finger protein 207 | 0.0266905 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0264909 |
| CLINT1 | clathrin interactor 1 | 0.0264565 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0263609 |
| COPS2 | COP9 signalosome subunit 2 | 0.0263183 |
| RHEB | Ras homolog enriched in brain | 0.026222 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261277 |
| CDH13 | cadherin 13 | 0.0261138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.0932869 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0799211 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0678706 |
| MT2A | metallothionein 2A | -0.0607257 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0599345 |
| OSMR | oncostatin M receptor | -0.0559837 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0540949 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0493694 |
| TGM2 | transglutaminase 2 | -0.0478522 |
| EFNA5 | ephrin-A5 | -0.0447552 |
| NRP1 | neuropilin 1 | -0.0447292 |
| GLCCI1 | glucocorticoid induced 1 | -0.043079 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0398854 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0388647 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0355617 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350186 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0341546 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0339217 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.033323 |
| ATXN1 | ataxin 1 | -0.0331863 |
| SMAD3 | SMAD family member 3 | -0.0328916 |
| ANGPTL4 | angiopoietin-like 4 | -0.031896 |
| KYNU | kynureninase | -0.0304215 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0303933 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0298105 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0295962 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0293059 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.029188 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0291473 |
| ETV6 | ets variant 6 | -0.0286739 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0284717 |
| RAD51B | RAD51 paralog B | -0.028146 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.02806 |
| NPC1 | Niemann-Pick disease, type C1 | -0.02778 |
| DUSP5 | dual specificity phosphatase 5 | -0.0276384 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0276224 |
| EGFR | epidermal growth factor receptor | -0.0272972 |
| FNBP1 | formin binding protein 1 | -0.0272564 |
| BPTF | bromodomain PHD finger transcription factor | -0.026652 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0266105 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0263968 |
| SLFN5 | schlafen family member 5 | -0.0253972 |
| HMGA2 | high mobility group AT-hook 2 | -0.0253959 |
| HLA-B | major histocompatibility complex, class I, B | -0.0249719 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0249556 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0249435 |
| VEGFA | vascular endothelial growth factor A | -0.023586 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0230234 |
| RND3 | Rho family GTPase 3 | -0.0228258 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0227349 |
| CDCP1 | CUB domain containing protein 1 | -0.0226997 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0226125 |
| PRELID2 | PRELI domain containing 2 | -0.0224309 |
| ADAR | adenosine deaminase, RNA-specific | -0.0224256 |
| H1-0 | H1.0 linker histone | -0.021712 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0214115 |
| ZNF385D | zinc finger protein 385D | -0.0214016 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0213593 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0212922 |
| NAV2 | neuron navigator 2 | -0.021071 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0209718 |
| EGR1 | early growth response 1 | -0.0203957 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0197183 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0195368 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0194471 |
| STK38L | serine/threonine kinase 38 like | -0.0193809 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.019299 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0192146 |
| ECE1 | endothelin converting enzyme 1 | -0.0191533 |
| NCOA7 | nuclear receptor coactivator 7 | -0.019124 |
| ITGB5 | integrin, beta 5 | -0.0189725 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0186783 |
| CA12 | carbonic anhydrase XII | -0.0185687 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0181314 |
| FOXP1 | forkhead box P1 | -0.0180131 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0179782 |
| LAMA4 | laminin, alpha 4 | -0.0175408 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0174215 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0172446 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0171097 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0168922 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0167341 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0166938 |
| CAB39 | calcium binding protein 39 | -0.0162634 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0161341 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0159877 |
| FHL2 | four and a half LIM domains 2 | -0.0159467 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0158619 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.015744 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0156266 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0156142 |
| CFDP1 | craniofacial development protein 1 | -0.015573 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0155597 |
| TUT7 | terminal uridylyl transferase 7 | -0.015532 |
| RUNX1 | runt-related transcription factor 1 | -0.0155008 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0153739 |
| ARFGEF3 | ARFGEF family member 3 | -0.0152861 |
| RPS2 | ribosomal protein S2 | -0.0152273 |
| FAM3C | family with sequence similarity 3, member C | -0.0152049 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0151077 |
