| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PGK1 | phosphoglycerate kinase 1 | 0.125772 |
| FN1 | fibronectin 1 | 0.113846 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.109001 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.098603 |
| SLTM | SAFB-like, transcription modulator | 0.0954474 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0755243 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0747852 |
| COG5 | component of oligomeric golgi complex 5 | 0.0723985 |
| RPL26 | ribosomal protein L26 | 0.069791 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0694028 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0693935 |
| VIM | vimentin | 0.0682352 |
| EFNA5 | ephrin-A5 | 0.0666741 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0658466 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0648971 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0633706 |
| RPS8 | ribosomal protein S8 | 0.0631437 |
| RAD51B | RAD51 paralog B | 0.0616359 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0612611 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0598496 |
| ASPH | aspartate beta-hydroxylase | 0.0595707 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0589362 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0580915 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0567989 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0536788 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.052953 |
| MATR3 | matrin 3 | 0.0526436 |
| TOP1 | topoisomerase (DNA) I | 0.0514779 |
| FLNB | filamin B, beta | 0.0503818 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0489016 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0473832 |
| USP34 | ubiquitin specific peptidase 34 | 0.0459516 |
| NPAS2 | neuronal PAS domain protein 2 | 0.045242 |
| SBF2 | SET binding factor 2 | 0.0438848 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0438389 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0428045 |
| FTL | ferritin, light polypeptide | 0.0421142 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0412002 |
| GOLGA4 | golgin A4 | 0.0398554 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0398551 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0394231 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0384808 |
| SP100 | SP100 nuclear antigen | 0.0383788 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0382615 |
| EHBP1 | EH domain binding protein 1 | 0.0379129 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0377244 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.037547 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0372771 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0357897 |
| RBM25 | RNA binding motif protein 25 | 0.0355166 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0353943 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345943 |
| DENND1A | DENN/MADD domain containing 1A | 0.0345936 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0339548 |
| RPL11 | ribosomal protein L11 | 0.0336933 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0334905 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0334185 |
| PHF21A | PHD finger protein 21A | 0.0331315 |
| ITGA6 | integrin, alpha 6 | 0.032109 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0317451 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0315789 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0313252 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0311454 |
| SPAG9 | sperm associated antigen 9 | 0.03101 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0307308 |
| PDE10A | phosphodiesterase 10A | 0.0305178 |
| ACTG1 | actin gamma 1 | 0.030503 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0304878 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0301296 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0299407 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.029737 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294422 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0291135 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0285741 |
| TMSB10 | thymosin beta 10 | 0.0285106 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0280697 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0275677 |
| TES | testin LIM domain protein | 0.0269643 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.026947 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0268131 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0267945 |
| CALD1 | caldesmon 1 | 0.0266374 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0265119 |
| PCBP2 | poly(rC) binding protein 2 | 0.0265086 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0263583 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0256816 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0255526 |
| INHBA | inhibin, beta A | 0.0253178 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.02526 |
| YEATS2 | YEATS domain containing 2 | 0.0251898 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0250191 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0248899 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0245146 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0243232 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0242577 |
| RBM39 | RNA binding motif protein 39 | 0.0241758 |
| SEPTIN7 | septin 7 | 0.0240088 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.023999 |
| QKI | QKI, KH domain containing, RNA binding | 0.0239718 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0238299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.155042 |
| MUC16 | mucin 16, cell surface associated | -0.134153 |
| GRB10 | growth factor receptor-bound protein 10 | -0.133734 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.114276 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.109833 |
| NDRG1 | N-myc downstream regulated 1 | -0.10812 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.103102 |
| MYO1E | myosin IE | -0.102642 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.102382 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0975992 |
| KRT17 | keratin 17, type I | -0.0885266 |
| LAMB3 | laminin, beta 3 | -0.086996 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.086473 |
| SVIL | supervillin | -0.0851224 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0820695 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.081001 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0793143 |
| IGF1R | insulin-like growth factor 1 receptor | -0.078496 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0778508 |
| TJP1 | tight junction protein 1 | -0.0743497 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0737804 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0717138 |
| MYO5B | myosin VB | -0.071531 |
| JUP | junction plakoglobin | -0.0680606 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0678167 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0674104 |
| EZR | ezrin | -0.0669224 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0662769 |
| DSPP | dentin sialophosphoprotein | -0.0660868 |
| OGA | O-GlcNAcase | -0.065534 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0642075 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0634118 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0632988 |
| UBC | ubiquitin C | -0.0626395 |
| ERBIN | erbb2 interacting protein | -0.0625402 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0624351 |
| SQSTM1 | sequestosome 1 | -0.0615816 |
| S100A10 | S100 calcium binding protein A10 | -0.0614815 |
| ABHD17C | abhydrolase domain containing 17C | -0.0613857 |
| KYNU | kynureninase | -0.0612464 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0575276 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0558677 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0550333 |
| FNIP1 | folliculin interacting protein 1 | -0.0546013 |
| STC1 | stanniocalcin 1 | -0.0545233 |
| MXD1 | MAX dimerization protein 1 | -0.0538505 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0526935 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0521178 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0519572 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0512283 |
| NPTN | neuroplastin | -0.0460479 |
| IGF2 | insulin-like growth factor 2 | -0.0453212 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0447691 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0445985 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0445867 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0439946 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0437571 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0426192 |
| ZNF292 | zinc finger protein 292 | -0.0424383 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0419013 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0418664 |
| ZNF395 | zinc finger protein 395 | -0.0416208 |
| AHNAK | AHNAK nucleoprotein | -0.0416192 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0412068 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0408666 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0407507 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0405278 |
| H3-3B | H3.3 histone B | -0.0401014 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0394566 |
| ATOSA | atos homolog A | -0.0393537 |
| ATXN1 | ataxin 1 | -0.038495 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0380946 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0373069 |
| FOXO3 | forkhead box O3 | -0.037011 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0366853 |
| NAV2 | neuron navigator 2 | -0.0351424 |
| FNDC3A | fibronectin type III domain containing 3A | -0.034973 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0345303 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0340784 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0339535 |
| MED13 | mediator complex subunit 13 | -0.0339002 |
| OSMR | oncostatin M receptor | -0.0330231 |
| RBM47 | RNA binding motif protein 47 | -0.0328939 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0326968 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325011 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0323384 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0317747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310831 |
| PERP | PERP, TP53 apoptosis effector | -0.0310006 |
| SETD2 | SET domain containing 2 | -0.0306456 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0305727 |
| LMO7 | LIM domain 7 | -0.030223 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0296877 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0296574 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0294888 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0290467 |
| FMNL2 | formin-like 2 | -0.0286064 |
| RASA2 | RAS p21 protein activator 2 | -0.028345 |
| LDHA | lactate dehydrogenase A | -0.0281015 |
| DSCAM | Down syndrome cell adhesion molecule | -0.027283 |
