| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hesperidin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hesperidin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.147905 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126848 |
| SPAG9 | sperm associated antigen 9 | 0.0906854 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0812829 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0743076 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0710845 |
| CADM1 | cell adhesion molecule 1 | 0.0675167 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0591552 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0576636 |
| ZNF292 | zinc finger protein 292 | 0.0570328 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0554262 |
| ATP13A3 | ATPase type 13A3 | 0.0517649 |
| HELZ | helicase with zinc finger | 0.0504084 |
| QKI | QKI, KH domain containing, RNA binding | 0.0495348 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0456286 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.045103 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0448302 |
| FN1 | fibronectin 1 | 0.0444564 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0444108 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0430798 |
| RYBP | RING1 and YY1 binding protein | 0.0427433 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0415829 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410023 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403815 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0391078 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0388084 |
| POTEF | POTE ankyrin domain family, member F | 0.0387195 |
| WTAP | Wilms tumor 1 associated protein | 0.0385812 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0384735 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0374731 |
| CCNL1 | cyclin L1 | 0.0361082 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.036018 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0357873 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0355603 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354832 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0353766 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0352649 |
| MSN | moesin | 0.0348568 |
| YBX1 | Y box binding protein 1 | 0.0347566 |
| OGA | O-GlcNAcase | 0.0337227 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0331392 |
| TFG | TRK-fused gene | 0.0330879 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330466 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0321635 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0321479 |
| CRY1 | cryptochrome circadian clock 1 | 0.0316997 |
| MATR3 | matrin 3 | 0.0310583 |
| DENND5A | DENN/MADD domain containing 5A | 0.0310034 |
| ANXA2 | annexin A2 | 0.0300215 |
| IPO7 | importin 7 | 0.0297158 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0294763 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293693 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0286227 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0285545 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0284133 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0283695 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0281607 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280711 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0275759 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0275566 |
| UBC | ubiquitin C | 0.0271368 |
| USP12 | ubiquitin specific peptidase 12 | 0.0271173 |
| ZNF207 | zinc finger protein 207 | 0.0268159 |
| NCKAP1 | NCK-associated protein 1 | 0.0266383 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0264444 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0263382 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0261265 |
| RNF145 | ring finger protein 145 | 0.0260681 |
| SRGN | serglycin | 0.0258293 |
| RAB1A | RAB1A, member RAS oncogene family | 0.025526 |
| UVRAG | UV radiation resistance associated | 0.0253977 |
| WDR43 | WD repeat domain 43 | 0.0250936 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0249053 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0248828 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0245849 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0242857 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0242463 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0242027 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.024124 |
| DSTN | destrin (actin depolymerizing factor) | 0.0240399 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0239682 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0239028 |
| ABI1 | abl-interactor 1 | 0.023869 |
| RPLP0 | ribosomal protein, large, P0 | 0.0238643 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0237587 |
| CKAP5 | cytoskeleton associated protein 5 | 0.02321 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.023201 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0231405 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0230732 |
| NUP58 | nucleoporin 58 | 0.0230232 |
| NEK7 | NIMA-related kinase 7 | 0.0229894 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0228973 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0228087 |
| NAV2 | neuron navigator 2 | 0.0227913 |
| ANLN | anillin, actin binding protein | 0.0227637 |
| SNX9 | sorting nexin 9 | 0.0226607 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0224618 |
| RLF | rearranged L-myc fusion | 0.0223391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0223282 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.176921 |
| TMSB10 | thymosin beta 10 | -0.107109 |
| HLA-B | major histocompatibility complex, class I, B | -0.10329 |
| MT2A | metallothionein 2A | -0.101213 |
| GLIS3 | GLIS family zinc finger 3 | -0.0882772 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0783944 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0759415 |
| NDRG1 | N-myc downstream regulated 1 | -0.0642837 |
| FRMD4A | FERM domain containing 4A | -0.0617366 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.060967 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0555717 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0516768 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0507456 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0504723 |
| HMGA2 | high mobility group AT-hook 2 | -0.0467923 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0461331 |
| CD44 | CD44 molecule (Indian blood group) | -0.0455985 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0452848 |
| BICC1 | BicC family RNA binding protein 1 | -0.0433796 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0416203 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0411019 |
| ATXN1 | ataxin 1 | -0.0399271 |
| EGR1 | early growth response 1 | -0.0384265 |
| FTL | ferritin, light polypeptide | -0.0383747 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0373737 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0373532 |
| RPS3 | ribosomal protein S3 | -0.0354087 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0351325 |
| EGFR | epidermal growth factor receptor | -0.0348103 |
| RAI14 | retinoic acid induced 14 | -0.0344665 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0341937 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0323304 |
| RPS19 | ribosomal protein S19 | -0.0321535 |
| RPL37A | ribosomal protein L37a | -0.0320726 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0319776 |
| EXT1 | exostosin glycosyltransferase 1 | -0.031566 |
| RPL35A | ribosomal protein L35a | -0.0311913 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0311486 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308823 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0307553 |
| RPL36 | ribosomal protein L36 | -0.0303307 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0285627 |
| RPL9 | ribosomal protein L9 | -0.0272543 |
| DIAPH2 | diaphanous-related formin 2 | -0.026798 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0263786 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0262538 |
| RNF213 | ring finger protein 213 | -0.0258784 |
| NAV1 | neuron navigator 1 | -0.0253195 |
| RPS12 | ribosomal protein S12 | -0.0247928 |
| RPL36A | ribosomal protein L36a | -0.0246464 |
| PRELID2 | PRELI domain containing 2 | -0.0246281 |
| HLA-A | major histocompatibility complex, class I, A | -0.0244869 |
| COL1A1 | collagen, type I, alpha 1 | -0.0243572 |
| RPL19 | ribosomal protein L19 | -0.0242845 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0242264 |
| TNS3 | tensin 3 | -0.0242167 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0240929 |
| AFF3 | AF4/FMR2 family, member 3 | -0.024086 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0238568 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0235732 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0235376 |
| RPS21 | ribosomal protein S21 | -0.0235128 |
| GOLGB1 | golgin B1 | -0.0233691 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0230613 |
| CLMP | CXADR-like membrane protein | -0.0229916 |
| DST | dystonin | -0.0229284 |
| VEGFA | vascular endothelial growth factor A | -0.0229106 |
| TOX2 | TOX high mobility group box family member 2 | -0.0228425 |
| RPL38 | ribosomal protein L38 | -0.0226392 |
| RPL26 | ribosomal protein L26 | -0.0225375 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0221484 |
| SP100 | SP100 nuclear antigen | -0.0221112 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0220635 |
| OSMR | oncostatin M receptor | -0.0218537 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0217991 |
| RPS13 | ribosomal protein S13 | -0.0217951 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0217379 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0216334 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0214388 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0213665 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0213443 |
| GPC6 | glypican 6 | -0.0213173 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0213119 |
| RRBP1 | ribosome binding protein 1 | -0.0212637 |
| HDAC8 | histone deacetylase 8 | -0.0210167 |
| MYO9A | myosin IXA | -0.0209302 |
| LDHA | lactate dehydrogenase A | -0.0208815 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0206478 |
| RPL35 | ribosomal protein L35 | -0.0206273 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0205444 |
| EFNA5 | ephrin-A5 | -0.0202514 |
| CEP112 | centrosomal protein 112kDa | -0.0201507 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0201458 |
| RPL31 | ribosomal protein L31 | -0.0197666 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0196272 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0195004 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0194464 |
| TMEM132D | transmembrane protein 132D | -0.0194106 |
| KLF6 | Kruppel-like factor 6 | -0.0193756 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0193735 |