Heterochromatin Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A compact and highly condensed form of chromatin. (Gene Ontology, GO_0000792)
External Link http://amigo.geneontology.org/amigo/term/GO:0000792
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Genes

51 proteins localized to the Heterochromatin cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MPHOSPH8 M-phase phosphoprotein 8 5.0
HMGA2 high mobility group AT-hook 2 5.0
SNAI1 snail family zinc finger 1 5.0
SIRT1 sirtuin 1 5.0
IKZF1 IKAROS family zinc finger 1 (Ikaros) 5.0
CDKN2A cyclin-dependent kinase inhibitor 2A 5.0
H2AZ1 H2A.Z variant histone 1 5.0
PSIP1 PC4 and SFRS1 interacting protein 1 5.0
CENPC centromere protein C 5.0
SIRT6 sirtuin 6 5.0
HMGA1 high mobility group AT-hook 1 5.0
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 5.0
FLYWCH1 FLYWCH-type zinc finger 1 5.0
LRWD1 leucine-rich repeats and WD repeat domain containing 1 5.0
INCENP inner centromere protein antigens 135/155kDa 5.0
MECP2 methyl CpG binding protein 2 5.0
H1-5 H1.5 linker histone, cluster member 5.0
BEND3 BEN domain containing 3 5.0
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 5.0
TASOR transcription activation suppressor 5.0
SALL1 spalt-like transcription factor 1 5.0
CNOT12 CCR4-NOT transcription complex subunit 12 5.0
UHRF1 ubiquitin-like with PHD and ring finger domains 1 5.0
FOXC1 forkhead box C1 5.0
MORC2 MORC family CW-type zinc finger 2 5.0
H1-4 H1.4 linker histone, cluster member 5.0
BAZ2A bromodomain adjacent to zinc finger domain, 2A 4.0
KMT5C lysine methyltransferase 5C 4.0
ZBTB18 zinc finger and BTB domain containing 18 4.0
MACROH2A1 macroH2A.1 histone 4.0
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 4.0
NCAPD3 non-SMC condensin II complex, subunit D3 4.0
HELLS helicase, lymphoid-specific 4.0
ANAPC7 anaphase promoting complex subunit 7 4.0
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 4.0
WDR76 WD repeat domain 76 4.0
CHD6 chromodomain helicase DNA binding protein 6 4.0
ZNF618 zinc finger protein 618 4.0
SIRT2 sirtuin 2 4.0
CBX3 chromobox homolog 3 4.0
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 4.0
ATRX alpha thalassemia/mental retardation syndrome X-linked 3.0
CHRAC1 chromatin accessibility complex 1 3.0
CBX5 chromobox homolog 5 3.0
CBX2 chromobox homolog 2 3.0
CBX1 chromobox homolog 1 3.0
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 3.0
BAZ1A bromodomain adjacent to zinc finger domain, 1A 3.0
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 3.0
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 3.0
BAZ1B bromodomain adjacent to zinc finger domain, 1B 3.0