| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hexylresorcinol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hexylresorcinol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.209662 |
| MT2A | metallothionein 2A | 0.111112 |
| FBN1 | fibrillin 1 | 0.110689 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.092554 |
| CD44 | CD44 molecule (Indian blood group) | 0.0741429 |
| B2M | beta-2-microglobulin | 0.0568538 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0505537 |
| STC1 | stanniocalcin 1 | 0.0498706 |
| COL1A2 | collagen, type I, alpha 2 | 0.0490141 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0439493 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0433902 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0399013 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0385747 |
| MYADM | myeloid-associated differentiation marker | 0.0376103 |
| SBF2 | SET binding factor 2 | 0.0372679 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0357589 |
| MT1X | metallothionein 1X | 0.0337517 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0330231 |
| UBC | ubiquitin C | 0.0316858 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0295593 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0288976 |
| GPC6 | glypican 6 | 0.0270997 |
| MB21D2 | Mab-21 domain containing 2 | 0.0269655 |
| TMSB10 | thymosin beta 10 | 0.0261365 |
| CLU | clusterin | 0.0252966 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0248141 |
| OGA | O-GlcNAcase | 0.0243336 |
| COL3A1 | collagen, type III, alpha 1 | 0.0238643 |
| LDHA | lactate dehydrogenase A | 0.0234921 |
| RNF145 | ring finger protein 145 | 0.0230134 |
| SDC4 | syndecan 4 | 0.0223584 |
| ATP13A3 | ATPase type 13A3 | 0.0223326 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0222445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0217653 |
| OPTN | optineurin | 0.0214359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0213323 |
| KIFAP3 | kinesin-associated protein 3 | 0.0211713 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0209623 |
| TXNIP | thioredoxin interacting protein | 0.0208628 |
| RBM25 | RNA binding motif protein 25 | 0.020739 |
| PGK1 | phosphoglycerate kinase 1 | 0.0204081 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0203367 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0201275 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0201143 |
| CD99 | CD99 molecule | 0.0199342 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0195073 |
| S100A10 | S100 calcium binding protein A10 | 0.0192908 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0191815 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0191206 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0190975 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0190899 |
| TAGLN2 | transgelin 2 | 0.0190296 |
| RTN4 | reticulon 4 | 0.0190006 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0186375 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0186169 |
| ARRDC3 | arrestin domain containing 3 | 0.0183899 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0181425 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0174803 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0173945 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0173332 |
| EGR1 | early growth response 1 | 0.0171349 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0170726 |
| TAPBP | TAP binding protein (tapasin) | 0.0169579 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.016782 |
| C1D | C1D nuclear receptor corepressor | 0.0167731 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0167718 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0166999 |
| PRKD3 | protein kinase D3 | 0.0166818 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0163751 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0162461 |
| TMOD1 | tropomodulin 1 | 0.0162141 |
| PFN1 | profilin 1 | 0.0161672 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0161109 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0160949 |
| TDRD7 | tudor domain containing 7 | 0.0160391 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0158977 |
| SMIM44 | small integral membrane protein 44 | 0.015847 |
| WTAP | Wilms tumor 1 associated protein | 0.0157362 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0157073 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0156615 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0155079 |
| PML | promyelocytic leukemia | 0.0154931 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0154076 |
| HLA-B | major histocompatibility complex, class I, B | 0.0153852 |
| FRMD5 | FERM domain containing 5 | 0.0153505 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0152912 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0152178 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0152021 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0150922 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0149914 |
| PLAT | plasminogen activator, tissue | 0.0149617 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0148782 |
| ZNF292 | zinc finger protein 292 | 0.0148072 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0147786 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0146978 |
| LOX | lysyl oxidase | 0.0145434 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0145213 |
| SNX9 | sorting nexin 9 | 0.0145041 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0143753 |
| TRIM56 | tripartite motif containing 56 | 0.0143737 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.201733 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.166745 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.16218 |
| COL5A1 | collagen, type V, alpha 1 | -0.152308 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.115843 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.115391 |
| SLC39A11 | solute carrier family 39, member 11 | -0.111027 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0965762 |
| AHNAK | AHNAK nucleoprotein | -0.0956506 |
| EGFR | epidermal growth factor receptor | -0.087083 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0632653 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0618693 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0613278 |
| MSI2 | musashi RNA-binding protein 2 | -0.0608264 |
| FN1 | fibronectin 1 | -0.0589193 |
| EFNA5 | ephrin-A5 | -0.0578382 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0542219 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0525324 |
| CCND1 | cyclin D1 | -0.0522423 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0507124 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0495416 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0479377 |
| CUX1 | cut-like homeobox 1 | -0.0471131 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0462092 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.045377 |
| CANX | calnexin | -0.0436062 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0433586 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0422617 |
| RIGI | RNA sensor RIG-I | -0.0406647 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0403239 |
| PTMA | prothymosin, alpha | -0.0401314 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0399484 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0397117 |
| NAV1 | neuron navigator 1 | -0.0384472 |
| FSTL1 | follistatin-like 1 | -0.038039 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0374369 |
| PODXL | podocalyxin-like | -0.0368703 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0365118 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0363554 |
| INTS6 | integrator complex subunit 6 | -0.0358252 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0356705 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0350832 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0350819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0343083 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0336716 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0332982 |
| TENM3 | teneurin transmembrane protein 3 | -0.0332943 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0330289 |
| PLXNA2 | plexin A2 | -0.0324245 |
| ASPH | aspartate beta-hydroxylase | -0.0324147 |
| AUTS2 | autism susceptibility candidate 2 | -0.032064 |
| TPM4 | tropomyosin 4 | -0.0312096 |
| CYTH3 | cytohesin 3 | -0.0301971 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0298816 |
| CAVIN1 | caveolae associated protein 1 | -0.0297797 |
| TNS3 | tensin 3 | -0.0296009 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0284816 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0283931 |
| MCL1 | myeloid cell leukemia 1 | -0.0283756 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0279288 |
| CALR | calreticulin | -0.0273479 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0272355 |
| IL7R | interleukin 7 receptor | -0.0271315 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0269456 |
| LMNA | lamin A/C | -0.0265169 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.0265045 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0262609 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262336 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0260989 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0259834 |
| FMN2 | formin 2 | -0.0252783 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0250235 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0247349 |
| RPL35A | ribosomal protein L35a | -0.0245738 |
| PDE10A | phosphodiesterase 10A | -0.0245541 |
| ACTG1 | actin gamma 1 | -0.0245248 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0244445 |
| DCLK2 | doublecortin-like kinase 2 | -0.0243472 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0242782 |
| ANKRD30B | ankyrin repeat domain 30B | -0.0239374 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0228128 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0227324 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0225931 |
| DENND1A | DENN/MADD domain containing 1A | -0.0223946 |
| FRMD4A | FERM domain containing 4A | -0.0223551 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0222344 |
| PCDH7 | protocadherin 7 | -0.021838 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0218108 |
| KIAA1549L | KIAA1549-like | -0.0217852 |
| MED13L | mediator complex subunit 13-like | -0.0217699 |
| TOX | thymocyte selection-associated high mobility group box | -0.0217094 |
| KRT81 | keratin 81, type II | -0.0216703 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0212692 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0211638 |
| SRPK2 | SRSF protein kinase 2 | -0.021021 |
| AEBP2 | AE binding protein 2 | -0.0209547 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0208115 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0205715 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0205015 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0204983 |