| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hexylresorcinol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Hexylresorcinol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.137513 |
| TMEM41B | transmembrane protein 41B | 0.101829 |
| MMP12 | matrix metallopeptidase 12 | 0.101178 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0960509 |
| JMJD1C | jumonji domain containing 1C | 0.0958951 |
| VIM | vimentin | 0.09034 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0835037 |
| RTN4 | reticulon 4 | 0.0833383 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.072967 |
| AHNAK | AHNAK nucleoprotein | 0.072589 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.071746 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0661899 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0642766 |
| NLGN1 | neuroligin 1 | 0.0624458 |
| VMP1 | vacuole membrane protein 1 | 0.0607641 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0603235 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0577425 |
| TXNRD1 | thioredoxin reductase 1 | 0.052085 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0510872 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0493664 |
| EDARADD | EDAR-associated death domain | 0.0493049 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0488472 |
| XPO1 | exportin 1 | 0.0463875 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0462454 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0453265 |
| KIF18B | kinesin family member 18B | 0.0451271 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0445405 |
| KPNB1 | karyopherin (importin) beta 1 | 0.041672 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0409874 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0392799 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0378301 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.03734 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.037054 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0368084 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0366119 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.036395 |
| MKI67 | marker of proliferation Ki-67 | 0.0363167 |
| SESN2 | sestrin 2 | 0.0360828 |
| MAP1B | microtubule-associated protein 1B | 0.0353853 |
| CDK17 | cyclin-dependent kinase 17 | 0.0350539 |
| PCDH7 | protocadherin 7 | 0.0349982 |
| CCN2 | cellular communication network factor 2 | 0.0345867 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0343283 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0341114 |
| SBF2 | SET binding factor 2 | 0.0338058 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0331787 |
| ANXA1 | annexin A1 | 0.031835 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0315937 |
| YEATS2 | YEATS domain containing 2 | 0.0311598 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0310377 |
| USP34 | ubiquitin specific peptidase 34 | 0.0308993 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0306614 |
| PGK1 | phosphoglycerate kinase 1 | 0.0305462 |
| TNPO1 | transportin 1 | 0.0304193 |
| EZR | ezrin | 0.0300972 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0287887 |
| MTAP | methylthioadenosine phosphorylase | 0.028491 |
| YBX3 | Y box binding protein 3 | 0.0284675 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0281507 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0278094 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.026939 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0268985 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0268338 |
| YAP1 | Yes-associated protein 1 | 0.026354 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0259812 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0253517 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0252492 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0252358 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.025191 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.025072 |
| DST | dystonin | 0.0250502 |
| NHSL1 | NHS-like 1 | 0.0250424 |
| S100A6 | S100 calcium binding protein A6 | 0.0247351 |
| FOSL1 | FOS-like antigen 1 | 0.0247301 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.0243627 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0241293 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.023998 |
| FHIT | fragile histidine triad | 0.0237889 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.023621 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0236147 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0235536 |
| FAM110C | family with sequence similarity 110, member C | 0.0234595 |
| MAP4 | microtubule-associated protein 4 | 0.0233944 |
| CMIP | c-Maf inducing protein | 0.0233747 |
| PRKCI | protein kinase C, iota | 0.0232574 |
| ETV5 | ets variant 5 | 0.0231465 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0229202 |
| DENND5B | DENN/MADD domain containing 5B | 0.0229011 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0226852 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0223368 |
| PTMS | parathymosin | 0.0223305 |
| ZFP64 | ZFP64 zinc finger protein | 0.0222884 |
| NEBL | nebulette | 0.0220782 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0220177 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0218618 |
| KLF6 | Kruppel-like factor 6 | 0.021633 |
| NUP58 | nucleoporin 58 | 0.0215372 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0214515 |
| ANK2 | ankyrin 2, neuronal | 0.021308 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0211642 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225683 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.181692 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.128447 |
| HMGA2 | high mobility group AT-hook 2 | -0.0799483 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0784722 |
| INTS6 | integrator complex subunit 6 | -0.0778387 |
| TMSB10 | thymosin beta 10 | -0.073549 |
| PTMA | prothymosin, alpha | -0.0699762 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0699259 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0668501 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0622138 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0618073 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0559851 |
| MGAT4C | MGAT4 family, member C | -0.0551162 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0524512 |
| TUBA1B | tubulin, alpha 1b | -0.0513768 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0509117 |
| HDAC9 | histone deacetylase 9 | -0.0491763 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0476249 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0451139 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0449618 |
| TENM3 | teneurin transmembrane protein 3 | -0.043484 |
| ADIPOR2 | adiponectin receptor 2 | -0.0419038 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0418646 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0416275 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0404812 |
| TPI1 | triosephosphate isomerase 1 | -0.0404257 |
| YBX1 | Y box binding protein 1 | -0.0398134 |
| DENND5A | DENN/MADD domain containing 5A | -0.0379041 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0368599 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368468 |
| FTL | ferritin, light polypeptide | -0.0354806 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0353171 |
| GOLGB1 | golgin B1 | -0.0348721 |
| HMGA1 | high mobility group AT-hook 1 | -0.0348555 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0345562 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0343496 |
| RPL23 | ribosomal protein L23 | -0.0340984 |
| RPS3 | ribosomal protein S3 | -0.0340533 |
| SERTAD2 | SERTA domain containing 2 | -0.0340307 |
| TBCA | tubulin folding cofactor A | -0.0328909 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0327871 |
| RPS19 | ribosomal protein S19 | -0.0316998 |
| PFN1 | profilin 1 | -0.0316324 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0304642 |
| PCDH9 | protocadherin 9 | -0.0298744 |
| LDHA | lactate dehydrogenase A | -0.0295074 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0293674 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0290755 |
| BRD2 | bromodomain containing 2 | -0.0288555 |
| LRRC23 | leucine rich repeat containing 23 | -0.0287062 |
| RPS8 | ribosomal protein S8 | -0.0286825 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0284442 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0282999 |
| POTEF | POTE ankyrin domain family, member F | -0.0280918 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0277609 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0276627 |
| EGR1 | early growth response 1 | -0.0276056 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0272228 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0271649 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0270837 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0269993 |
| AEBP2 | AE binding protein 2 | -0.0269694 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.02681 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0265931 |
| AREG | amphiregulin | -0.0263406 |
| RPL8 | ribosomal protein L8 | -0.0261257 |
| MORF4L2 | mortality factor 4 like 2 | -0.0260762 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0259626 |
| INTS4 | integrator complex subunit 4 | -0.0256123 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0255763 |
| RPL7 | ribosomal protein L7 | -0.025318 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0251131 |
| HMGB1 | high mobility group box 1 | -0.0248107 |
| RYK | receptor-like tyrosine kinase | -0.0247759 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0247585 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0246971 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0240247 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0240117 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.0237424 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0236713 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0235805 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0234783 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0231472 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0231277 |
| HDLBP | high density lipoprotein binding protein | -0.0231014 |
| USP15 | ubiquitin specific peptidase 15 | -0.0230948 |
| TEX14 | testis expressed 14 | -0.0227124 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0223593 |
| RPS13 | ribosomal protein S13 | -0.0223479 |
| UBAP2 | ubiquitin associated protein 2 | -0.0217228 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0217158 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0216634 |
| ACTG1 | actin gamma 1 | -0.021508 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0213979 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0212377 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0212372 |
| SON | SON DNA binding protein | -0.0212224 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0211868 |
| LDHB | lactate dehydrogenase B | -0.0209405 |
