| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hexylresorcinol perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hexylresorcinol_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.204744 |
| TXNRD1 | thioredoxin reductase 1 | 0.18792 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.107218 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.106434 |
| CES1 | carboxylesterase 1 | 0.097144 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0911736 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0844333 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.077884 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0577991 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0575319 |
| STC1 | stanniocalcin 1 | 0.0547975 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0534726 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0530352 |
| MKI67 | marker of proliferation Ki-67 | 0.0530195 |
| OSMR | oncostatin M receptor | 0.0491159 |
| PGK1 | phosphoglycerate kinase 1 | 0.04758 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0461375 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0435773 |
| MT2A | metallothionein 2A | 0.0393238 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0391512 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0347978 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0327092 |
| LAMA4 | laminin, alpha 4 | 0.0320067 |
| ADAR | adenosine deaminase, RNA-specific | 0.0307846 |
| CDCP1 | CUB domain containing protein 1 | 0.0297117 |
| TRIM56 | tripartite motif containing 56 | 0.0293421 |
| B2M | beta-2-microglobulin | 0.028636 |
| CPE | carboxypeptidase E | 0.0281025 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0280017 |
| ZNF292 | zinc finger protein 292 | 0.0278581 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0276115 |
| NGLY1 | N-glycanase 1 | 0.0274079 |
| SMAD3 | SMAD family member 3 | 0.0273883 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0271434 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0266905 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.026589 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0258151 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0257383 |
| TMEM45B | transmembrane protein 45B | 0.0251187 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0239969 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0239314 |
| LAMC2 | laminin, gamma 2 | 0.0238493 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0234058 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0229145 |
| CAB39 | calcium binding protein 39 | 0.022834 |
| SLC38A1 | solute carrier family 38, member 1 | 0.022815 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0227734 |
| NDRG1 | N-myc downstream regulated 1 | 0.0225281 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0223701 |
| HLA-B | major histocompatibility complex, class I, B | 0.0220915 |
| RNF149 | ring finger protein 149 | 0.0219153 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0218427 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0214346 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.021344 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0212659 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0208619 |
| WDR26 | WD repeat domain 26 | 0.0206527 |
| ARRDC3 | arrestin domain containing 3 | 0.020534 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0202905 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0201491 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0199065 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0198878 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0197839 |
| EFNA5 | ephrin-A5 | 0.0194783 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0194506 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0190158 |
| SYAP1 | synapse associated protein 1 | 0.0189666 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0186124 |
| KIAA1217 | KIAA1217 | 0.0186066 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0184197 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0183565 |
| FRY | furry homolog (Drosophila) | 0.0181948 |
| LAMB3 | laminin, beta 3 | 0.0181834 |
| YBX3 | Y box binding protein 3 | 0.0180146 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0176977 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0176194 |
| UBE4A | ubiquitination factor E4A | 0.0171759 |
| PIR | pirin (iron-binding nuclear protein) | 0.0171561 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0171243 |
| RTN4 | reticulon 4 | 0.0168664 |
| RNF169 | ring finger protein 169 | 0.016835 |
| N4BP1 | NEDD4 binding protein 1 | 0.0167831 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0165832 |
| AHNAK | AHNAK nucleoprotein | 0.0164739 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0161842 |
| MX1 | MX dynamin-like GTPase 1 | 0.0161468 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0160616 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0159943 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0159276 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0159251 |
| PLAUR | plasminogen activator, urokinase receptor | 0.015846 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0157785 |
| LDHA | lactate dehydrogenase A | 0.0156471 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0155718 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0155049 |
| NEK7 | NIMA-related kinase 7 | 0.0153379 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.015141 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0148977 |
| MLKL | mixed lineage kinase domain-like | 0.0148919 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0148889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.149949 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.136803 |
| INTS6 | integrator complex subunit 6 | -0.133859 |
| ASPH | aspartate beta-hydroxylase | -0.131764 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.116543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0973377 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0966827 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0920011 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0797458 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0792977 |
| SCEL | sciellin | -0.0708064 |
| MYOF | myoferlin | -0.0689406 |
| HOMER1 | homer scaffolding protein 1 | -0.0612651 |
| NABP1 | nucleic acid binding protein 1 | -0.0590623 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0580115 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0565158 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0545435 |
| LMO7 | LIM domain 7 | -0.0474389 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0454449 |
| SPAG9 | sperm associated antigen 9 | -0.0443825 |
| SLTM | SAFB-like, transcription modulator | -0.0429863 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0410919 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0401309 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0381442 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0378287 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0357664 |
| MORF4L2 | mortality factor 4 like 2 | -0.0348234 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0341949 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0339054 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0337946 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.033675 |
| MYO1E | myosin IE | -0.0330699 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0328959 |
| PTMA | prothymosin, alpha | -0.0328922 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0322986 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0315046 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0312847 |
| SEC61G | Sec61 gamma subunit | -0.0312791 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0309838 |
| VCL | vinculin | -0.0309533 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0305148 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0304718 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0301513 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0299031 |
| MCU | mitochondrial calcium uniporter | -0.0296722 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0292693 |
| PTK2 | protein tyrosine kinase 2 | -0.029007 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.028941 |
| USP53 | ubiquitin specific peptidase 53 | -0.0287752 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0287715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0285733 |
| CTBP2 | C-terminal binding protein 2 | -0.0285374 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0281297 |
| CUX1 | cut-like homeobox 1 | -0.0280098 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0276624 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0269873 |
| RCOR1 | REST corepressor 1 | -0.026864 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267006 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0266311 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0265222 |
| GPC6 | glypican 6 | -0.0261696 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0260183 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0251962 |
| PRKCA | protein kinase C, alpha | -0.0249018 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0247825 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.024619 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0243776 |
| AEBP2 | AE binding protein 2 | -0.0242444 |
| FBXO11 | F-box protein 11 | -0.0241412 |
| MAP7 | microtubule-associated protein 7 | -0.0238893 |
| OXSR1 | oxidative stress responsive 1 | -0.0236355 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0234374 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0233673 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0232713 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0231802 |
| HYOU1 | hypoxia up-regulated 1 | -0.0231552 |
| FLNB | filamin B, beta | -0.0228077 |
| ANXA2 | annexin A2 | -0.0226143 |
| MAGT1 | magnesium transporter 1 | -0.0225852 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0225756 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0221808 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0220418 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.021694 |
| RASAL2 | RAS protein activator like 2 | -0.021624 |
| PDE8A | phosphodiesterase 8A | -0.0214794 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0213349 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0212406 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0211314 |
| TMSB10 | thymosin beta 10 | -0.0210139 |
| WASF2 | WAS protein family, member 2 | -0.0208219 |
| PLS3 | plastin 3 | -0.0207094 |
| KRT86 | keratin 86, type II | -0.0207066 |
| HELZ | helicase with zinc finger | -0.0205658 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0204965 |
| CD163L1 | CD163 molecule-like 1 | -0.0204651 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0202946 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0201883 |
| TUFT1 | tuftelin 1 | -0.0200373 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0199175 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0198253 |
