| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hexylresorcinol perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hexylresorcinol_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0884753 |
| NDRG1 | N-myc downstream regulated 1 | 0.0760854 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0658479 |
| ATXN1 | ataxin 1 | 0.0573006 |
| FAT1 | FAT atypical cadherin 1 | 0.0569486 |
| FN1 | fibronectin 1 | 0.0556231 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0548432 |
| GPC6 | glypican 6 | 0.0546192 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0543118 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0540803 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0526475 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0523674 |
| EGR1 | early growth response 1 | 0.0517977 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.05045 |
| RAD51B | RAD51 paralog B | 0.0493141 |
| MT2A | metallothionein 2A | 0.0482903 |
| CD44 | CD44 molecule (Indian blood group) | 0.0462622 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0451422 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0423054 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0421499 |
| MYO1E | myosin IE | 0.0419292 |
| TNS3 | tensin 3 | 0.0405318 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0404968 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0399983 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0396364 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0395728 |
| EGFR | epidermal growth factor receptor | 0.0393461 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0386535 |
| AHNAK | AHNAK nucleoprotein | 0.0386495 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0378747 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0373261 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0372398 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.03703 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.036958 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0367287 |
| JAK1 | Janus kinase 1 | 0.0363193 |
| IGF2 | insulin-like growth factor 2 | 0.0362751 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.035896 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0358578 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0353966 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0352173 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0351654 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0351487 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0344289 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0340175 |
| TUT4 | terminal uridylyl transferase 4 | 0.0340133 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0337622 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0329566 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0327349 |
| SQSTM1 | sequestosome 1 | 0.0326944 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.032681 |
| PRKCE | protein kinase C, epsilon | 0.0326677 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0325966 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0325374 |
| NHSL1 | NHS-like 1 | 0.0324045 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0323494 |
| DGKH | diacylglycerol kinase, eta | 0.0321843 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0319486 |
| EZR | ezrin | 0.0318832 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0316733 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0316418 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0307937 |
| AXL | AXL receptor tyrosine kinase | 0.030699 |
| DST | dystonin | 0.0306125 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0305587 |
| RNF213 | ring finger protein 213 | 0.0303494 |
| IER3 | immediate early response 3 | 0.0302636 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0302113 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.030138 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0300897 |
| FAM120B | family with sequence similarity 120B | 0.0299381 |
| SPIDR | scaffolding protein involved in DNA repair | 0.029877 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0297613 |
| WWC1 | WW and C2 domain containing 1 | 0.0297043 |
| HMGB1 | high mobility group box 1 | 0.0297014 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0296482 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0293951 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0293877 |
| TUT7 | terminal uridylyl transferase 7 | 0.0292598 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0289765 |
| YTHDC1 | YTH domain containing 1 | 0.0288455 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286415 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0285667 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 0.0284564 |
| INTS6 | integrator complex subunit 6 | 0.0283158 |
| RPL4 | ribosomal protein L4 | 0.0283122 |
| DUSP5 | dual specificity phosphatase 5 | 0.0282946 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0280768 |
| SMAD3 | SMAD family member 3 | 0.0280259 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0279846 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0279147 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0278944 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0277091 |
| EHBP1 | EH domain binding protein 1 | 0.0276873 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0276637 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0275113 |
| GPATCH2L | G patch domain containing 2-like | 0.0273316 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0271111 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0269285 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0269167 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.120498 |
| FTL | ferritin, light polypeptide | -0.110779 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.107791 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0946759 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0897038 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0881728 |
| SRPK2 | SRSF protein kinase 2 | -0.0880358 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0839059 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0798901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0789466 |
| NPTN | neuroplastin | -0.0754572 |
| LAMB3 | laminin, beta 3 | -0.0735086 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0733796 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0677008 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0668432 |
| RPS19 | ribosomal protein S19 | -0.0620354 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.061447 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.060146 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0596606 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0589605 |
| TXNRD1 | thioredoxin reductase 1 | -0.0587769 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0582586 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0581145 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0576001 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0568631 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0557085 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.055331 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0552512 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0552484 |
| PTK2 | protein tyrosine kinase 2 | -0.0537375 |
| DICER1 | dicer 1, ribonuclease type III | -0.0533027 |
| RNF149 | ring finger protein 149 | -0.0526044 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0511585 |
| WDR45B | WD repeat domain 45B | -0.0509675 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.050562 |
| TMSB10 | thymosin beta 10 | -0.0498769 |
| GOLGA4 | golgin A4 | -0.0493471 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0484038 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0477174 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0475737 |
| ANXA2 | annexin A2 | -0.0473244 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0467216 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0464178 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0456953 |
| TXNIP | thioredoxin interacting protein | -0.0454546 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0452006 |
| MXD1 | MAX dimerization protein 1 | -0.0448139 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0439266 |
| TMSB4X | thymosin beta 4, X-linked | -0.0429446 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0418713 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0417526 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0416452 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0406798 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0402784 |
| DENND4C | DENN/MADD domain containing 4C | -0.0397634 |
| SCFD1 | sec1 family domain containing 1 | -0.0394157 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0393849 |
| RBM39 | RNA binding motif protein 39 | -0.0391521 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0390782 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.039058 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.038441 |
| SPAG9 | sperm associated antigen 9 | -0.0381847 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0373436 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0373011 |
| B2M | beta-2-microglobulin | -0.0372223 |
| SSH2 | slingshot protein phosphatase 2 | -0.0367396 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0364614 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0358647 |
| RPL35A | ribosomal protein L35a | -0.0343078 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0340417 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0340273 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0338998 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0338587 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0334379 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0334161 |
| S100A10 | S100 calcium binding protein A10 | -0.0333908 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.033369 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0329347 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0325286 |
| DENND4A | DENN/MADD domain containing 4A | -0.0324695 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0323623 |
| RPL12 | ribosomal protein L12 | -0.0320535 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0319451 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0317211 |
| AFAP1 | actin filament associated protein 1 | -0.0315652 |
| FNBP4 | formin binding protein 4 | -0.0314586 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311128 |
| RPS24 | ribosomal protein S24 | -0.031026 |
| STAG2 | stromal antigen 2 | -0.0307586 |
| KRT17 | keratin 17, type I | -0.030713 |
| SDC4 | syndecan 4 | -0.0305035 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0304804 |
| PTMA | prothymosin, alpha | -0.0304683 |
| OGA | O-GlcNAcase | -0.0299613 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0299419 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0299356 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0298593 |
| EFNA5 | ephrin-A5 | -0.0296184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0295786 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0294814 |
