| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Hexylresorcinol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Hexylresorcinol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.329565 |
| FN1 | fibronectin 1 | 0.204956 |
| COL5A2 | collagen, type V, alpha 2 | 0.121605 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.116766 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.115327 |
| PDE10A | phosphodiesterase 10A | 0.0889024 |
| CDH13 | cadherin 13 | 0.081733 |
| EFNA5 | ephrin-A5 | 0.0808164 |
| PCBP3 | poly(rC) binding protein 3 | 0.0745243 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0712629 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0645877 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0640215 |
| PYGL | phosphorylase, glycogen, liver | 0.0638558 |
| SMYD3 | SET and MYND domain containing 3 | 0.0625135 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0613605 |
| GDA | guanine deaminase | 0.0597751 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0596323 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0587282 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0561009 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0560585 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0510767 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.049054 |
| NPAS2 | neuronal PAS domain protein 2 | 0.048838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0488268 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.04878 |
| TBXT | T-box transcription factor T | 0.0474857 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0473536 |
| AHNAK | AHNAK nucleoprotein | 0.0460914 |
| CD109 | CD109 molecule | 0.0459085 |
| GPRIN3 | GPRIN family member 3 | 0.0438347 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0436863 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0436684 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.041966 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0378118 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0377564 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0345804 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0328269 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0325798 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0323906 |
| PTGR1 | prostaglandin reductase 1 | 0.0320584 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0320157 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315656 |
| NHSL1 | NHS-like 1 | 0.0302664 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0299208 |
| CRLF2 | cytokine receptor-like factor 2 | 0.0294794 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0292922 |
| RPL4 | ribosomal protein L4 | 0.0290677 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0282209 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0276025 |
| AUTS2 | autism susceptibility candidate 2 | 0.0274137 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0267262 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0263155 |
| RPLP1 | ribosomal protein, large, P1 | 0.0262826 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0257983 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0257629 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0254621 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0251396 |
| ANXA2 | annexin A2 | 0.0250206 |
| INHBA | inhibin, beta A | 0.0246795 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.024603 |
| NRG1 | neuregulin 1 | 0.0242109 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0241064 |
| NRCAM | neuronal cell adhesion molecule | 0.0232554 |
| RAD51B | RAD51 paralog B | 0.0230242 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0229744 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0229404 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0226933 |
| FAM13A | family with sequence similarity 13, member A | 0.022336 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.0218973 |
| ALPK2 | alpha-kinase 2 | 0.0213105 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0212779 |
| BMERB1 | bMERB domain containing 1 | 0.021007 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0209846 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0209501 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0207274 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0200899 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0197141 |
| DNER | delta/notch-like EGF repeat containing | 0.0196182 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0194809 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0191652 |
| OSMR | oncostatin M receptor | 0.0190587 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0190529 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0189353 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0187616 |
| INVS | inversin | 0.0186773 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0184254 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0182979 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0181971 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0180407 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0180315 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.0174589 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0170636 |
| RHOB | ras homolog family member B | 0.0169485 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0167236 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.016706 |
| MAP7 | microtubule-associated protein 7 | 0.0165521 |
| PRELID2 | PRELI domain containing 2 | 0.0161455 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0160837 |
| GRAMD1B | GRAM domain containing 1B | 0.0159954 |
| RPS27 | ribosomal protein S27 | 0.0159095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125205 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0777241 |
| VCL | vinculin | -0.0696909 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0678988 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.067622 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0648823 |
| INTS6 | integrator complex subunit 6 | -0.0460874 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0441877 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0437435 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0426605 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0419546 |
| KYNU | kynureninase | -0.0413718 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0410118 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0408887 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0392336 |
| ACTG1 | actin gamma 1 | -0.0391067 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0372962 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0363167 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0362733 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0358559 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0356073 |
| RPL9 | ribosomal protein L9 | -0.0353138 |
| MCL1 | myeloid cell leukemia 1 | -0.0338328 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0337819 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0328194 |
| SPAG9 | sperm associated antigen 9 | -0.0324973 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0321598 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0318225 |
| MORF4L2 | mortality factor 4 like 2 | -0.0312047 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0309999 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0309884 |
| SQSTM1 | sequestosome 1 | -0.0302672 |
| CANX | calnexin | -0.0300472 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0295512 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0293004 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0282408 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0280495 |
| EGR1 | early growth response 1 | -0.0278204 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0274086 |
| PTMA | prothymosin, alpha | -0.0268837 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.026093 |
| LDHA | lactate dehydrogenase A | -0.0259774 |
| B2M | beta-2-microglobulin | -0.0259369 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0257321 |
| PLCB4 | phospholipase C, beta 4 | -0.0256808 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0256393 |
| RPL37A | ribosomal protein L37a | -0.0253794 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0252804 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0251209 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0249319 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0241025 |
| GOLGA4 | golgin A4 | -0.0237434 |
| COPA | coatomer protein complex, subunit alpha | -0.023307 |
| MYOF | myoferlin | -0.023276 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0232628 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.023235 |
| SMAD2 | SMAD family member 2 | -0.0230599 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0224609 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0224467 |
| RPS24 | ribosomal protein S24 | -0.0223626 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0218907 |
| CLTC | clathrin, heavy chain (Hc) | -0.0217527 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0216382 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0215994 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0213575 |
| PCBP2 | poly(rC) binding protein 2 | -0.0206554 |
| RPL35A | ribosomal protein L35a | -0.0205808 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0201859 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0200666 |
| GOLGB1 | golgin B1 | -0.0200437 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0200366 |
| USP53 | ubiquitin specific peptidase 53 | -0.0199906 |
| TMSB10 | thymosin beta 10 | -0.0199044 |
| RPS27A | ribosomal protein S27a | -0.0196779 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.019301 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0192169 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0190257 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0189683 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.018843 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0188331 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.018814 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0186764 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0186638 |
| SETX | senataxin | -0.0185214 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0183741 |
| ANKRD17 | ankyrin repeat domain 17 | -0.018277 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0182652 |
| DSCAM | Down syndrome cell adhesion molecule | -0.018255 |
| FTL | ferritin, light polypeptide | -0.0181972 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0181809 |
| POTEF | POTE ankyrin domain family, member F | -0.0181746 |
| RPLP2 | ribosomal protein, large, P2 | -0.0181561 |
| VDAC1 | voltage-dependent anion channel 1 | -0.018088 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.018047 |
| RPS2 | ribosomal protein S2 | -0.0180409 |
| LMNA | lamin A/C | -0.0179312 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0179133 |
| BRD2 | bromodomain containing 2 | -0.0178486 |
| SRGN | serglycin | -0.0177617 |
| USP15 | ubiquitin specific peptidase 15 | -0.0176742 |
