Hidradenitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

279 genes co-occuring with the disease Hidradenitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
NCSTN nicastrin 3.074
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.938
IL17A interleukin 17A 2.881
PSENEN presenilin enhancer gamma secretase subunit 2.845
TNF tumor necrosis factor 2.837
IL1B interleukin 1, beta 2.51
IL36R interleukin 36 receptor 2.459
IL1A interleukin 1, alpha 2.433
IL36RN interleukin 36 receptor antagonist 2.378
MEFV Mediterranean fever 2.308
IL17F interleukin 17F 2.298
POGLUT1 protein O-glucosyltransferase 1 2.205
IL22 interleukin 22 2.19
IL6 interleukin 6 2.181
POFUT1 protein O-fucosyltransferase 1 2.164
PSEN1 presenilin 1 2.157
S100A7 S100 calcium binding protein A7 2.142
CRP C-reactive protein, pentraxin-related 2.142
CXCL8 chemokine (C-X-C motif) ligand 8 2.135
IFNG interferon, gamma 2.127
IL17C interleukin 17C 2.121
PDE4A phosphodiesterase 4A, cAMP-specific 2.075
DEFB4A defensin, beta 4A 2.026
CAMP cathelicidin antimicrobial peptide 2.02
IL10 interleukin 10 2.006
IL17RA interleukin 17 receptor A 2.003
CARD14 caspase recruitment domain family, member 14 1.987
NLRP3 NLR family, pyrin domain containing 3 1.986
APH1A APH1A gamma secretase subunit 1.976
JAK1 Janus kinase 1 1.975
S100A7A S100 calcium binding protein A7A 1.975
APH1B APH1B gamma secretase subunit 1.962
IL1F10 interleukin 1 family, member 10 (theta) 1.955
IL1RN interleukin 1 receptor antagonist 1.944
NOD2 nucleotide-binding oligomerization domain containing 2 1.933
LPIN2 lipin 2 1.928
CD4 CD4 molecule 1.926
FLG2 filaggrin family member 2 1.921
FLG filaggrin 1.92
DCD dermcidin 1.908
IL18 interleukin 18 1.906
IL4 interleukin 4 1.906
TYK2 tyrosine kinase 2 1.891
IL13 interleukin 13 1.861
IL36G interleukin 36, gamma 1.838
RNASE7 ribonuclease, RNase A family, 7 1.838
CSF3 colony stimulating factor 3 (granulocyte) 1.821
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.804
CCL20 chemokine (C-C motif) ligand 20 1.799
KRT16 keratin 16, type I 1.795
IL26 interleukin 26 1.791
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.787
IL1R1 interleukin 1 receptor, type I 1.784
IL1RAP interleukin 1 receptor accessory protein 1.784
IL37 interleukin 37 1.77
IRAK4 interleukin-1 receptor-associated kinase 4 1.767
MVK mevalonate kinase 1.765
IL32 interleukin 32 1.748
IL25 interleukin 25 1.741
IL19 interleukin 19 1.719
NLRP12 NLR family, pyrin domain containing 12 1.709
DEFB103A defensin, beta 103A 1.708
KRT17 keratin 17, type I 1.701
CD8A CD8a molecule 1.687
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.685
IFNA1 interferon, alpha 1 1.679
IL31 interleukin 31 1.665
IL23R interleukin 23 receptor 1.664
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.663
IL23A interleukin 23, alpha subunit p19 1.654
C5AR1 complement component 5a receptor 1 1.653
KRT5 keratin 5, type II 1.636
IL2 interleukin 2 1.614
IL33 interleukin 33 1.61
LCN2 lipocalin 2 1.609
DEFB4B defensin, beta 4B 1.608
IL5 interleukin 5 1.598
JAK3 Janus kinase 3 1.588
SYK spleen tyrosine kinase 1.588
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.584
PSEN2 presenilin 2 1.579
TLR2 toll-like receptor 2 1.572
IL12RB1 interleukin 12 receptor, beta 1 1.567
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.564
IL17D interleukin 17D 1.564
KRT6A keratin 6A, type II 1.561
CXCL10 chemokine (C-X-C motif) ligand 10 1.535
DSG1 desmoglein 1 1.516
TGFB1 transforming growth factor, beta 1 1.515
IL24 interleukin 24 1.507
JAK2 Janus kinase 2 1.499
GJB2 gap junction protein, beta 2, 26kDa 1.493
MPO myeloperoxidase 1.488
SPRR3 small proline-rich protein 3 1.478
CCL2 chemokine (C-C motif) ligand 2 1.477
IL36A interleukin 36, alpha 1.472
KRT10 keratin 10, type I 1.47
IL36B interleukin 36, beta 1.469
KRT77 keratin 77, type II 1.459
KRT79 keratin 79, type II 1.459
CXCL9 chemokine (C-X-C motif) ligand 9 1.455
INS insulin 1.454
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 1.45
LTA lymphotoxin alpha 1.427
PRTN3 proteinase 3 1.426
IL17B interleukin 17B 1.424
TLR4 toll-like receptor 4 1.423
TSLP thymic stromal lymphopoietin 1.422
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.419
IL18BP interleukin 18 binding protein 1.418
STAT1 signal transducer and activator of transcription 1, 91kDa 1.402
S100A12 S100 calcium binding protein A12 1.4
NLRP1 NLR family, pyrin domain containing 1 1.393
KLK5 kallikrein-related peptidase 5 1.39
IL1R2 interleukin 1 receptor, type II 1.387
CD1B CD1b molecule 1.384
KRT1 keratin 1, type II 1.382
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.379
IL17RC interleukin 17 receptor C 1.379
CD1C CD1c molecule 1.379
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.377
DNAL1 dynein, axonemal, light chain 1 1.376
CD1E CD1e molecule 1.374
CD1A CD1a molecule 1.363
NLRC4 NLR family, CARD domain containing 4 1.362
IL4R interleukin 4 receptor 1.359
LTA4H leukotriene A4 hydrolase 1.359
SPRR2D small proline-rich protein 2D 1.35
IL16 interleukin 16 1.346
APP amyloid beta (A4) precursor protein 1.344
IVL involucrin 1.343
DSG3 desmoglein 3 1.342
DEFB104B defensin, beta 104B 1.341
NOTCH1 notch 1 1.331
WDR1 WD repeat domain 1 1.331
ELANE elastase, neutrophil expressed 1.33
CCL5 chemokine (C-C motif) ligand 5 1.329
CXCR1 chemokine (C-X-C motif) receptor 1 1.325
AHR aryl hydrocarbon receptor 1.322
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.321
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 1.317
KRT72 keratin 72, type II 1.317
IL31RA interleukin 31 receptor A 1.316
IL15 interleukin 15 1.316
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.316
ELN elastin 1.314
CD68 CD68 molecule 1.31
KRT6B keratin 6B, type II 1.309
OTULIN OTU deubiquitinase with linear linkage specificity 1.309
IGF1 insulin-like growth factor 1 (somatomedin C) 1.306
COL17A1 collagen, type XVII, alpha 1 1.305
DEFB104A defensin, beta 104A 1.304
RETN resistin 1.295
LEP leptin 1.286
CXCL13 chemokine (C-X-C motif) ligand 13 1.283
CD1D CD1d molecule 1.283
BTK Bruton agammaglobulinemia tyrosine kinase 1.277
CXCL6 chemokine (C-X-C motif) ligand 6 1.275
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.27
ADIPOQ adiponectin, C1Q and collagen domain containing 1.269
MYD88 myeloid differentiation primary response 88 1.265
DEFB1 defensin, beta 1 1.261
MMP9 matrix metallopeptidase 9 1.26
IL9 interleukin 9 1.258
CCL17 chemokine (C-C motif) ligand 17 1.258
C3 complement component 3 1.257
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.247
KRT14 keratin 14, type I 1.245
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.244
TRAF3IP2 TRAF3 interacting protein 2 1.243
CXCL2 chemokine (C-X-C motif) ligand 2 1.243
IFNB1 interferon, beta 1, fibroblast 1.24
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.24
MASP2 mannan-binding lectin serine peptidase 2 1.238
DST dystonin 1.234
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.231
RETNLB resistin like beta 1.23
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.229
MMP1 matrix metallopeptidase 1 1.229
CTSG cathepsin G 1.227
PI3 peptidase inhibitor 3, skin-derived 1.227
HM13 histocompatibility (minor) 13 1.223
CXCL11 chemokine (C-X-C motif) ligand 11 1.223
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 1.215
ICAM1 intercellular adhesion molecule 1 1.212
ELOVL7 ELOVL fatty acid elongase 7 1.202
MMP8 matrix metallopeptidase 8 1.201
IL17RE interleukin 17 receptor E 1.2
SAA2 serum amyloid A2 1.197
AIM2 absent in melanoma 2 1.194
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.191
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 1.185
IFNA2 interferon, alpha 2 1.184
SAA1 serum amyloid A1 1.183
CD163 CD163 molecule 1.18
SHARPIN SHANK-associated RH domain interactor 1.18
CD40 CD40 molecule, TNF receptor superfamily member 5 1.178
LBR lamin B receptor 1.177
C5AR2 complement component 5a receptor 2 1.172
FOXP3 forkhead box P3 1.167
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.163
KLK7 kallikrein-related peptidase 7 1.16
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.154
IL2RA interleukin 2 receptor, alpha 1.142
CXCR2 chemokine (C-X-C motif) receptor 2 1.139
TLR9 toll-like receptor 9 1.137
IFI16 interferon, gamma-inducible protein 16 1.136
ALB albumin 1.134
IL10RB interleukin 10 receptor, beta 1.125
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.117
STAT4 signal transducer and activator of transcription 4 1.116
S100A9 S100 calcium binding protein A9 1.115
IL7 interleukin 7 1.114
IL18RAP interleukin 18 receptor accessory protein 1.113
IRAK1 interleukin-1 receptor-associated kinase 1 1.11
SELE selectin E 1.106
CD2 CD2 molecule 1.102
IL12RB2 interleukin 12 receptor, beta 2 1.1
TAC1 tachykinin, precursor 1 1.099
IFNA13 interferon, alpha 13 1.099
MX1 MX dynamin-like GTPase 1 1.097
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.097
IL17RB interleukin 17 receptor B 1.096
SHBG sex hormone-binding globulin 1.091
EGFR epidermal growth factor receptor 1.089
IFNA6 interferon, alpha 6 1.085
MMP3 matrix metallopeptidase 3 1.08
KRT15 keratin 15, type I 1.076
TCHHL1 trichohyalin-like 1 1.075
TLR7 toll-like receptor 7 1.075
IFNA17 interferon, alpha 17 1.073
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.073
GLB1L galactosidase, beta 1-like 1.073
MMP2 matrix metallopeptidase 2 1.072
IFNA10 interferon, alpha 10 1.07
IFNA7 interferon, alpha 7 1.07
IFNA5 interferon, alpha 5 1.068
IFNA4 interferon, alpha 4 1.065
FGF7 fibroblast growth factor 7 1.064
CRBN cereblon 1.062
PTPRC protein tyrosine phosphatase, receptor type, C 1.06
EGF epidermal growth factor 1.057
NAMPT nicotinamide phosphoribosyltransferase 1.056
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.056
IFNA16 interferon, alpha 16 1.054
IFNA21 interferon, alpha 21 1.053
IFNA14 interferon, alpha 14 1.053
IFNA8 interferon, alpha 8 1.053
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.047
CCL4 chemokine (C-C motif) ligand 4 1.045
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.042
OSMR oncostatin M receptor 1.04
CARD9 caspase recruitment domain family, member 9 1.039
CCL3 chemokine (C-C motif) ligand 3 1.039
GCG glucagon 1.039
SELL selectin L 1.035
CDSN corneodesmosin 1.035
IFNL1 interferon, lambda 1 1.034
SAA2-SAA4 SAA2-SAA4 readthrough 1.033
MC5R melanocortin 5 receptor 1.03
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.029
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.024
CXCL5 chemokine (C-X-C motif) ligand 5 1.024
RNF31 ring finger protein 31 1.023
TLR3 toll-like receptor 3 1.023
CCR6 chemokine (C-C motif) receptor 6 1.021
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.021
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.017
HK3 hexokinase 3 (white cell) 1.014
CCL19 chemokine (C-C motif) ligand 19 1.013
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.012
CXCR3 chemokine (C-X-C motif) receptor 3 1.008
ADAM17 ADAM metallopeptidase domain 17 1.007
STAT5B signal transducer and activator of transcription 5B 1.006
STAT2 signal transducer and activator of transcription 2, 113kDa 1.006
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.005
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.004
HLA-B major histocompatibility complex, class I, B 1.002
CD19 CD19 molecule 1.001