Histiocytoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A neoplasm consisting of histiocytes. Forms include BENIGN FIBROUS HISTIOCYTOMA; and MALIGNANT FIBROUS HISTIOCYTOMA (MeSH) (Experimental Factor Ontology, EFO_0005561)
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Genes

236 genes co-occuring with the disease Histiocytoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CD34 CD34 molecule 3.185
EWSR1 EWS RNA-binding protein 1 3.153
CD68 CD68 molecule 3.047
CD99 CD99 molecule 2.903
CD99L2 CD99 molecule-like 2 2.885
AK5 adenylate kinase 5 2.718
SOX10 SRY (sex determining region Y)-box 10 2.566
ALK anaplastic lymphoma receptor tyrosine kinase 2.531
CREB1 cAMP responsive element binding protein 1 2.523
CALD1 caldesmon 1 2.501
MME membrane metallo-endopeptidase 2.493
FUS FUS RNA binding protein 2.487
CD1A CD1a molecule 2.459
CD1E CD1e molecule 2.454
CD1B CD1b molecule 2.451
PECAM1 platelet/endothelial cell adhesion molecule 1 2.415
CREM cAMP responsive element modulator 2.391
CD1C CD1c molecule 2.373
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.346
PDGFB platelet-derived growth factor beta polypeptide 2.314
CD1D CD1d molecule 2.309
MITF microphthalmia-associated transcription factor 2.29
ATF1 activating transcription factor 1 2.279
CD163 CD163 molecule 2.266
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.224
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.223
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.21
MYOG myogenin (myogenic factor 4) 2.195
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 2.171
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.16
ENO2 enolase 2 (gamma, neuronal) 2.118
TP53 tumor protein p53 2.045
CREB3L2 cAMP responsive element binding protein 3-like 2 2.042
COL1A1 collagen, type I, alpha 1 2.042
KRT5 keratin 5, type II 2.004
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.998
USP6 ubiquitin specific peptidase 6 1.997
SSX2 synovial sarcoma, X breakpoint 2 1.978
CREB3L1 cAMP responsive element binding protein 3-like 1 1.955
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.946
S100A9 S100 calcium binding protein A9 1.946
MUC4 mucin 4, cell surface associated 1.93
ZNF444 zinc finger protein 444 1.929
WT1 Wilms tumor 1 1.919
SSX1 synovial sarcoma, X breakpoint 1 1.915
CD207 CD207 molecule, langerin 1.914
MYOD1 myogenic differentiation 1 1.907
SYP synaptophysin 1.903
BCL2 B-cell CLL/lymphoma 2 1.884
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.881
CCNB3 cyclin B3 1.847
ETV6 ets variant 6 1.845
KRT7 keratin 7, type II 1.835
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.815
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.806
NF1 neurofibromin 1 1.793
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.791
KRT20 keratin 20, type I 1.781
TFE3 transcription factor binding to IGHM enhancer 3 1.78
CDKN2A cyclin-dependent kinase inhibitor 2A 1.765
HAVCR1 hepatitis A virus cellular receptor 1 1.755
PGM1 phosphoglucomutase 1 1.746
ANO1 anoctamin 1, calcium activated chloride channel 1.744
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.738
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.735
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 1.734
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.729
ITGAD integrin, alpha D 1.712
SS18 synovial sarcoma translocation, chromosome 18 1.71
NUTM1 NUT midline carcinoma, family member 1 1.705
MMP11 matrix metallopeptidase 11 1.7
CALB2 calbindin 2 1.698
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 1.692
SSX4B synovial sarcoma, X breakpoint 4B 1.684
EML4 echinoderm microtubule associated protein like 4 1.682
SSX4 synovial sarcoma, X breakpoint 4 1.677
APOD apolipoprotein D 1.672
TP63 tumor protein p63 1.668
DUX4 double homeobox 4 1.661
PTPRC protein tyrosine phosphatase, receptor type, C 1.657
PRAME preferentially expressed antigen in melanoma 1.655
S100A6 S100 calcium binding protein A6 1.652
GFAP glial fibrillary acidic protein 1.648
CRTC1 CREB regulated transcription coactivator 1 1.647
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 1.647
B3GAT1 beta-1,3-glucuronyltransferase 1 1.644
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1.635
PRDM10 PR domain containing 10 1.635
NCAM1 neural cell adhesion molecule 1 1.626
PLAG1 pleiomorphic adenoma gene 1 1.615
DCTN1 dynactin 1 1.607
CAMTA1 calmodulin binding transcription activator 1 1.602
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.598
TYR tyrosinase 1.595
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.593
CLTC clathrin, heavy chain (Hc) 1.588
TPM3 tropomyosin 3 1.587
PDPN podoplanin 1.58
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.538
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.519
RRBP1 ribosome binding protein 1 1.513
NGFR nerve growth factor receptor 1.512
CDK4 cyclin-dependent kinase 4 1.512
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.507
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.501
F13A1 coagulation factor XIII, A1 polypeptide 1.488
TPM4 tropomyosin 4 1.485
NKX2-2 NK2 homeobox 2 1.484
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.484
ETV4 ets variant 4 1.48
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.474
ETV1 ets variant 1 1.466
PAX8 paired box 8 1.466
CCND1 cyclin D1 1.453
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.447
RANBP2 RAN binding protein 2 1.444
NCOA2 nuclear receptor coactivator 2 1.437
HRAS Harvey rat sarcoma viral oncogene homolog 1.433
SATB2 SATB homeobox 2 1.429
TERT telomerase reverse transcriptase 1.427
WWTR1 WW domain containing transcription regulator 1 1.425
NES nestin 1.411
KRT8 keratin 8, type II 1.409
KIRREL1 kirre like nephrin family adhesion molecule 1 1.408
SEC62 SEC62 homolog (S. cerevisiae) 1.408
TFCP2 transcription factor CP2 1.404
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.401
FSCN1 fascin actin-bundling protein 1 1.39
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.39
CD4 CD4 molecule 1.386
PBX3 pre-B-cell leukemia homeobox 3 1.381
PAX3 paired box 3 1.378
STRN striatin, calmodulin binding protein 1.37
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.367
MMP23B matrix metallopeptidase 23B 1.366
KIF5B kinesin family member 5B 1.361
FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.36
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 1.351
PRKCD protein kinase C, delta 1.35
PXDN peroxidasin 1.346
PXDNL peroxidasin-like 1.336
CD8A CD8a molecule 1.334
FGFR2 fibroblast growth factor receptor 2 1.318
MYH9 myosin, heavy chain 9, non-muscle 1.315
RET ret proto-oncogene 1.308
CD79A CD79a molecule, immunoglobulin-associated alpha 1.305
PAX7 paired box 7 1.291
COL6A3 collagen, type VI, alpha 3 1.287
SEC31A SEC31 homolog A (S. cerevisiae) 1.287
CD63 CD63 molecule 1.285
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.281
KRT19 keratin 19, type I 1.277
BEND2 BEN domain containing 2 1.276
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.26
SDC1 syndecan 1 1.257
EGFR epidermal growth factor receptor 1.254
MB myoglobin 1.251
GPR68 G protein-coupled receptor 68 1.243
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.233
PGR progesterone receptor 1.231
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.231
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.228
KRAS Kirsten rat sarcoma viral oncogene homolog 1.227
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.225
FN1 fibronectin 1 1.224
ZBED8L ZBED8 like 1.223
YAP1 Yes-associated protein 1 1.22
MT1E metallothionein 1E 1.214
FGFR1 fibroblast growth factor receptor 1 1.21
FOXO1 forkhead box O1 1.207
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.202
SPN sialophorin 1.2
KRT14 keratin 14, type I 1.2
PMEL premelanosome protein 1.196
FAT1 FAT atypical cadherin 1 1.194
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.19
TGFB1 transforming growth factor, beta 1 1.184
PRKCB protein kinase C, beta 1.182
HMBOX1 homeobox containing 1 1.181
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.173
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 1.172
SSX2B synovial sarcoma, X breakpoint 2B 1.168
CREB3L4 cAMP responsive element binding protein 3-like 4 1.165
AIF1 allograft inflammatory factor 1 1.163
PAX5 paired box 5 1.161
HMGA2 high mobility group AT-hook 2 1.158
CD248 CD248 molecule, endosialin 1.157
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.149
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.141
ESR1 estrogen receptor 1 1.133
MSR1 macrophage scavenger receptor 1 1.131
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.129
RREB1 ras responsive element binding protein 1 1.127
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.126
ZC3H7B zinc finger CCCH-type containing 7B 1.123
ERBB2 erb-b2 receptor tyrosine kinase 2 1.121
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.119
PRKCA protein kinase C, alpha 1.117
MLANA melan-A 1.113
FGF2 fibroblast growth factor 2 (basic) 1.111
NKX2-1 NK2 homeobox 1 1.11
MMP21 matrix metallopeptidase 21 1.109
KLF17 Kruppel-like factor 17 1.109
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 1.108
CD274 CD274 molecule 1.105
PTEN phosphatase and tensin homolog 1.102
TRIM11 tripartite motif containing 11 1.101
FGFR3 fibroblast growth factor receptor 3 1.097
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.095
LHFPL6 LHFPL tetraspan subfamily member 6 1.082
IL2 interleukin 2 1.079
CTSK cathepsin K 1.074
MMP1 matrix metallopeptidase 1 1.073
FGF23 fibroblast growth factor 23 1.073
CD5 CD5 molecule 1.066
TNF tumor necrosis factor 1.064
KRT15 keratin 15, type I 1.062
CD44 CD44 molecule (Indian blood group) 1.06
CHGA chromogranin A 1.056
VIM vimentin 1.056
CTHRC1 collagen triple helix repeat containing 1 1.054
PBX1 pre-B-cell leukemia homeobox 1 1.051
SQSTM1 sequestosome 1 1.051
NF2 neurofibromin 2 (merlin) 1.049
PTCH1 patched 1 1.049
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 1.046
SOX9 SRY (sex determining region Y)-box 9 1.042
IL6 interleukin 6 1.037
CRP C-reactive protein, pentraxin-related 1.036
MYH14 myosin, heavy chain 14, non-muscle 1.035
IFNG interferon, gamma 1.034
SRY sex determining region Y 1.032
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.03
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.023
PCNA proliferating cell nuclear antigen 1.011
OLIG2 oligodendrocyte lineage transcription factor 2 1.002