Histiocytosis, Langerhans-Cell Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0019621
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Genes

102 genes associated with the disease Histiocytosis, Langerhans-Cell in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMACR alpha-methylacyl-CoA racemase
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL17 chemokine (C-C motif) ligand 17
CCL22 chemokine (C-C motif) ligand 22
CCND1 cyclin D1
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD1A CD1a molecule
CD207 CD207 molecule, langerin
CD34 CD34 molecule
CD68 CD68 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFLAR CASP8 and FADD-like apoptosis regulator
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DCX doublecortin
EPHB2 EPH receptor B2
FADD Fas (TNFRSF6)-associated via death domain
FLT3LG fms-related tyrosine kinase 3 ligand
FOXP3 forkhead box P3
FSCN1 fascin actin-bundling protein 1
FSHR follicle stimulating hormone receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GSN gelsolin
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGH immunoglobulin heavy locus
IGK immunoglobulin kappa locus
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
INSL3 insulin-like 3 (Leydig cell)
JAG2 jagged 2
JAK2 Janus kinase 2
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LHCGR luteinizing hormone/choriogonadotropin receptor
LIF leukemia inhibitory factor
LYZ lysozyme
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MPO myeloperoxidase
MYD88 myeloid differentiation primary response 88
NOTCH1 notch 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OAT ornithine aminotransferase
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAX5 paired box 5
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLEKHA6 pleckstrin homology domain containing, family A member 6
POSTN periostin, osteoblast specific factor
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELN reelin
S100A1 S100 calcium binding protein A1
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOST sclerostin
SPP1 secreted phosphoprotein 1
STAB1 stabilin 1
STK11 serine/threonine kinase 11
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TUBA1A tubulin, alpha 1a
U2AF1 U2 small nuclear RNA auxiliary factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZHX2 zinc fingers and homeoboxes 2