| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.20224 |
| HDAC9 | histone deacetylase 9 | 0.164651 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.151212 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.148932 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.136038 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.134324 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.101048 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0940972 |
| KLF6 | Kruppel-like factor 6 | 0.0929199 |
| AHNAK | AHNAK nucleoprotein | 0.0866285 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0861047 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0742268 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0736615 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.073389 |
| NAV2 | neuron navigator 2 | 0.071911 |
| RND3 | Rho family GTPase 3 | 0.0705123 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0667009 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0653234 |
| FOSL1 | FOS-like antigen 1 | 0.0601568 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0595699 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0593022 |
| CDH13 | cadherin 13 | 0.0586598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0580572 |
| EGFR | epidermal growth factor receptor | 0.0544299 |
| SLFN5 | schlafen family member 5 | 0.0530383 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0485605 |
| FRMD6 | FERM domain containing 6 | 0.0483159 |
| ADM | adrenomedullin | 0.0478022 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0474569 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0468297 |
| RIGI | RNA sensor RIG-I | 0.0455759 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0455064 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0451432 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0451245 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0438686 |
| ZNF462 | zinc finger protein 462 | 0.0438452 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0438196 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0410997 |
| MCL1 | myeloid cell leukemia 1 | 0.0405559 |
| MMP12 | matrix metallopeptidase 12 | 0.0402848 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0396605 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.036532 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0354556 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.034873 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0342158 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337547 |
| FOSL2 | FOS-like antigen 2 | 0.0335502 |
| ERBIN | erbb2 interacting protein | 0.0335464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0334733 |
| SP100 | SP100 nuclear antigen | 0.0324197 |
| GPC6 | glypican 6 | 0.031969 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.031948 |
| NAV3 | neuron navigator 3 | 0.0317953 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0316908 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0307948 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0304848 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0304843 |
| RUNX1 | runt-related transcription factor 1 | 0.030056 |
| CDK6 | cyclin-dependent kinase 6 | 0.0299235 |
| TOX | thymocyte selection-associated high mobility group box | 0.0298162 |
| ATP13A3 | ATPase type 13A3 | 0.0297625 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0294824 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0294335 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0293859 |
| KIAA1217 | KIAA1217 | 0.0292448 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0285646 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0285497 |
| LDHA | lactate dehydrogenase A | 0.0282381 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0280786 |
| FNIP1 | folliculin interacting protein 1 | 0.0280354 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0277862 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0274929 |
| DST | dystonin | 0.0273657 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0263956 |
| RGS7 | regulator of G-protein signaling 7 | 0.0258801 |
| CENPF | centromere protein F, 350/400kDa | 0.0255953 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0254664 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0254567 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0254419 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0254136 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0252795 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0252011 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0251498 |
| NOCT | nocturnin | 0.0248116 |
| NLGN4Y | neuroligin 4, Y-linked | 0.0247432 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0244506 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0243009 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0238981 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0235614 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0231967 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0231165 |
| IL7R | interleukin 7 receptor | 0.023049 |
| TLE4 | transducin-like enhancer of split 4 | 0.0229002 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0228775 |
| LYST | lysosomal trafficking regulator | 0.0226141 |
| MED13 | mediator complex subunit 13 | 0.0224037 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0224017 |
| ANXA5 | annexin A5 | 0.022277 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0208402 |
| ZNF292 | zinc finger protein 292 | 0.020782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.221255 |
| VIM | vimentin | -0.134295 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132771 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.131804 |
| TMSB10 | thymosin beta 10 | -0.130469 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.107527 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105086 |
| NAV1 | neuron navigator 1 | -0.0885121 |
| LOX | lysyl oxidase | -0.0880392 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0857279 |
| FBN1 | fibrillin 1 | -0.0822213 |
| MT2A | metallothionein 2A | -0.0820146 |
| PODXL | podocalyxin-like | -0.0812476 |
| PLAT | plasminogen activator, tissue | -0.0802026 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0801379 |
| LOXL2 | lysyl oxidase-like 2 | -0.0729707 |
| PTMA | prothymosin, alpha | -0.0671555 |
| EGR1 | early growth response 1 | -0.0660287 |
| THBS2 | thrombospondin 2 | -0.058808 |
| COL3A1 | collagen, type III, alpha 1 | -0.0549494 |
| COL5A2 | collagen, type V, alpha 2 | -0.0543322 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0525155 |
| COL5A1 | collagen, type V, alpha 1 | -0.0494648 |
| MAP1B | microtubule-associated protein 1B | -0.0488344 |
| B2M | beta-2-microglobulin | -0.0472293 |
| FLNB | filamin B, beta | -0.0465691 |
| COL1A2 | collagen, type I, alpha 2 | -0.0463305 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0436097 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0430742 |
| CANX | calnexin | -0.0422523 |
| HLA-B | major histocompatibility complex, class I, B | -0.0417726 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0378997 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.037852 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.037618 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0370535 |
| UBC | ubiquitin C | -0.0370377 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368855 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0357289 |
| MEIS2 | Meis homeobox 2 | -0.0331211 |
| CSTB | cystatin B (stefin B) | -0.0330051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0324432 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0324411 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0322988 |
| CALR | calreticulin | -0.0321848 |
| PRSS23 | protease, serine, 23 | -0.0319486 |
| HDLBP | high density lipoprotein binding protein | -0.0317508 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0316462 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0314579 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0314013 |
| SQSTM1 | sequestosome 1 | -0.0311018 |
| INHBA | inhibin, beta A | -0.0309966 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0304199 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0293089 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0291892 |
| GNAS | GNAS complex locus | -0.0289224 |
| FN1 | fibronectin 1 | -0.0286659 |
| CTSB | cathepsin B | -0.0283718 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0281844 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0281359 |
| SBF2 | SET binding factor 2 | -0.0280624 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0277658 |
| CALU | calumenin | -0.0277315 |
| DCLK2 | doublecortin-like kinase 2 | -0.0272635 |
| IER2 | immediate early response 2 | -0.0271266 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0269641 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0269285 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0268054 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0262883 |
| FSTL1 | follistatin-like 1 | -0.0259634 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.0257339 |
| FTL | ferritin, light polypeptide | -0.0249731 |
| RTN4 | reticulon 4 | -0.0249256 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.0249202 |
| SUCNR1 | succinate receptor 1 | -0.0246199 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0245276 |
| MAP4 | microtubule-associated protein 4 | -0.0243683 |
| TUBB | tubulin, beta class I | -0.0239802 |
| NDRG1 | N-myc downstream regulated 1 | -0.023781 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0237554 |
| SPAG9 | sperm associated antigen 9 | -0.0233092 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0230818 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0228541 |
| COPA | coatomer protein complex, subunit alpha | -0.0226687 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0226138 |
| HLA-C | major histocompatibility complex, class I, C | -0.0223527 |
| MYADM | myeloid-associated differentiation marker | -0.0220097 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0219057 |
| CD99 | CD99 molecule | -0.021618 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0215043 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0214158 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.021356 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.021243 |
| GLIS3 | GLIS family zinc finger 3 | -0.0210279 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0209728 |
| GLG1 | golgi glycoprotein 1 | -0.0209232 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.020921 |
| INSIG1 | insulin induced gene 1 | -0.020827 |
| S100A6 | S100 calcium binding protein A6 | -0.0206654 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0206523 |
