| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.136851 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.114528 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.103666 |
| DSPP | dentin sialophosphoprotein | 0.103629 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.10182 |
| C3 | complement component 3 | 0.0991879 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.087115 |
| SVIL | supervillin | 0.0785445 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0764666 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0753293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0695517 |
| FN1 | fibronectin 1 | 0.0603535 |
| PLIN2 | perilipin 2 | 0.0512185 |
| ENO1 | enolase 1, (alpha) | 0.0508615 |
| PTCHD4 | patched domain containing 4 | 0.047303 |
| PEG3 | paternally expressed 3 | 0.0469032 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0464154 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0455119 |
| RAD51B | RAD51 paralog B | 0.045097 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0424271 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422546 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0387129 |
| SKIL | SKI-like proto-oncogene | 0.0375937 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0356037 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0342242 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0333855 |
| DTNA | dystrobrevin, alpha | 0.0329272 |
| SEPTIN9 | septin 9 | 0.0319141 |
| DST | dystonin | 0.0316664 |
| FAM107B | family with sequence similarity 107, member B | 0.0316071 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302414 |
| FAT1 | FAT atypical cadherin 1 | 0.0299056 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0298646 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0290885 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0282365 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.027349 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0271566 |
| FOXP1 | forkhead box P1 | 0.0260833 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0256599 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0252927 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0241855 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0238585 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0234907 |
| TNS1 | tensin 1 | 0.0227838 |
| TPM4 | tropomyosin 4 | 0.0225137 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.022208 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219457 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205449 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0199773 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0194533 |
| KIAA1217 | KIAA1217 | 0.0192051 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0190225 |
| PKM | pyruvate kinase, muscle | 0.0189002 |
| ATXN1 | ataxin 1 | 0.0188402 |
| RAI14 | retinoic acid induced 14 | 0.0186063 |
| GK | glycerol kinase | 0.0183973 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0183827 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0180366 |
| DUSP16 | dual specificity phosphatase 16 | 0.017876 |
| PGK1 | phosphoglycerate kinase 1 | 0.0177878 |
| NDRG1 | N-myc downstream regulated 1 | 0.0176953 |
| BCL2L1 | BCL2-like 1 | 0.0176306 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0173089 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0172269 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0172098 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0170079 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0167699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0166335 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0166181 |
| TPM1 | tropomyosin 1 (alpha) | 0.0165455 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0165266 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0163287 |
| ASPH | aspartate beta-hydroxylase | 0.0158836 |
| AHR | aryl hydrocarbon receptor | 0.0153601 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0153263 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0153003 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0152553 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0151178 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0151124 |
| H1-0 | H1.0 linker histone | 0.0150549 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0149215 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0147314 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0146416 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0146124 |
| VCL | vinculin | 0.0145037 |
| SMAD3 | SMAD family member 3 | 0.0144208 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0141221 |
| ITGAV | integrin, alpha V | 0.0140735 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0138893 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0138139 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0137216 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0136677 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0136558 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0136296 |
| KRT23 | keratin 23, type I | 0.0133809 |
| PCGF5 | polycomb group ring finger 5 | 0.0132977 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0132907 |
| HDAC4 | histone deacetylase 4 | 0.0132893 |
| ZNF292 | zinc finger protein 292 | 0.0132874 |
| EXOC4 | exocyst complex component 4 | 0.0132242 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.489528 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0890195 |
| TRIM26 | tripartite motif containing 26 | -0.0699826 |
| APOB | apolipoprotein B | -0.0687593 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0668212 |
| GPC3 | glypican 3 | -0.0579975 |
| RBM39 | RNA binding motif protein 39 | -0.0508723 |
| RPS6 | ribosomal protein S6 | -0.0476161 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.0476047 |
| TF | transferrin | -0.0434223 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0398807 |
| HMGA1 | high mobility group AT-hook 1 | -0.0385658 |
| GNAS | GNAS complex locus | -0.0356377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.034504 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0338566 |
| RPS24 | ribosomal protein S24 | -0.032115 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0318699 |
| RRBP1 | ribosome binding protein 1 | -0.0309542 |
| A2M | alpha-2-macroglobulin | -0.0309092 |
| GPC6 | glypican 6 | -0.030786 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0305652 |
| FTL | ferritin, light polypeptide | -0.0302656 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.029792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0297148 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0295991 |
| RPS12 | ribosomal protein S12 | -0.0291245 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0287198 |
| RBM25 | RNA binding motif protein 25 | -0.0281409 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0279578 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0276301 |
| SDC4 | syndecan 4 | -0.0272093 |
| CP | ceruloplasmin (ferroxidase) | -0.0271732 |
| SQSTM1 | sequestosome 1 | -0.026713 |
| LAMB3 | laminin, beta 3 | -0.0264621 |
| RPL11 | ribosomal protein L11 | -0.0256466 |
| RPL37A | ribosomal protein L37a | -0.0256447 |
| NPR2 | natriuretic peptide receptor 2 | -0.0251633 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0250607 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0243641 |
| RPS2 | ribosomal protein S2 | -0.0240947 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0237966 |
| MATR3 | matrin 3 | -0.023508 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0227952 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0224199 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0221034 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0220319 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0220122 |
| TXNRD1 | thioredoxin reductase 1 | -0.021882 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0209099 |
| RPL10A | ribosomal protein L10a | -0.0208678 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0208475 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0207369 |
| H3-3B | H3.3 histone B | -0.0207103 |
| RPL38 | ribosomal protein L38 | -0.0206456 |
| RPL5 | ribosomal protein L5 | -0.0206003 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0204773 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0203347 |
| RPS27A | ribosomal protein S27a | -0.0202629 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0202374 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0198903 |
| PTMA | prothymosin, alpha | -0.0197384 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0196561 |
| MIDN | midnolin | -0.01965 |
| RPS3 | ribosomal protein S3 | -0.0193413 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0192292 |
| TFRC | transferrin receptor | -0.0190696 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0189381 |
| APOA2 | apolipoprotein A-II | -0.0188493 |
| RPL4 | ribosomal protein L4 | -0.018689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0186676 |
| RPLP1 | ribosomal protein, large, P1 | -0.0186376 |
| RPS8 | ribosomal protein S8 | -0.0185321 |
| TOP1 | topoisomerase (DNA) I | -0.0185094 |
| GDF15 | growth differentiation factor 15 | -0.0184531 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0183585 |
| YME1L1 | YME1-like 1 ATPase | -0.0183244 |
| RPL37 | ribosomal protein L37 | -0.018156 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0181083 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0178174 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0174471 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.017223 |
| NOP56 | NOP56 ribonucleoprotein | -0.0171814 |
| ZFR | zinc finger RNA binding protein | -0.0169762 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0167082 |
| MAP1B | microtubule-associated protein 1B | -0.0166132 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0164217 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0164133 |
| EPAS1 | endothelial PAS domain protein 1 | -0.016407 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0163331 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0161814 |
| FUS | FUS RNA binding protein | -0.016133 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0161041 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.016091 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0160906 |
| RPS19 | ribosomal protein S19 | -0.0160849 |
| CUL3 | cullin 3 | -0.0160321 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.01594 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0158141 |
| B2M | beta-2-microglobulin | -0.015631 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.015614 |
