| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.032584 |
| CDK6 | cyclin-dependent kinase 6 | 0.0239286 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0214502 |
| RASAL2 | RAS protein activator like 2 | 0.0207212 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0192084 |
| DST | dystonin | 0.0188866 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0178734 |
| EMP1 | epithelial membrane protein 1 | 0.0169802 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0168264 |
| RIN2 | Ras and Rab interactor 2 | 0.0156294 |
| EGFR | epidermal growth factor receptor | 0.0149982 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0141724 |
| ASPH | aspartate beta-hydroxylase | 0.0134887 |
| CEP250 | centrosomal protein 250kDa | 0.0132012 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0129079 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0122164 |
| RAI14 | retinoic acid induced 14 | 0.0122138 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0121761 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0115442 |
| JAG1 | jagged 1 | 0.0112738 |
| EZR | ezrin | 0.0108684 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0107168 |
| KIAA0040 | KIAA0040 | 0.010701 |
| PHF14 | PHD finger protein 14 | 0.00993865 |
| RPL7 | ribosomal protein L7 | 0.00986059 |
| ADM | adrenomedullin | 0.00980204 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00975968 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00966488 |
| CDCP1 | CUB domain containing protein 1 | 0.00957184 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00950131 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00914352 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.00910365 |
| MYOF | myoferlin | 0.00897037 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00881576 |
| SMAD3 | SMAD family member 3 | 0.00880482 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.00871454 |
| EFHD2 | EF-hand domain family, member D2 | 0.00850352 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.00847063 |
| PLK2 | polo-like kinase 2 | 0.00845731 |
| TBC1D2 | TBC1 domain family, member 2 | 0.00843077 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00830782 |
| LIMD1 | LIM domains containing 1 | 0.00825272 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0082465 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00821334 |
| TXNRD1 | thioredoxin reductase 1 | 0.00821279 |
| MSN | moesin | 0.00799761 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00798385 |
| OSMR | oncostatin M receptor | 0.00794784 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00785707 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00782742 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00774604 |
| SYNJ2 | synaptojanin 2 | 0.00769724 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00748616 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.00731856 |
| ARRDC3 | arrestin domain containing 3 | 0.00723609 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00718646 |
| ITGB4 | integrin, beta 4 | 0.00717674 |
| SEPTIN9 | septin 9 | 0.00699409 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00698952 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.00691326 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00689151 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00683925 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.00683445 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00682296 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00680791 |
| ANXA2 | annexin A2 | 0.00680653 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00678254 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00670013 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.00669596 |
| SLK | STE20-like kinase | 0.00664475 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0065439 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.00649609 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00647737 |
| TGM2 | transglutaminase 2 | 0.00646517 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00644049 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.00642849 |
| CD47 | CD47 molecule | 0.00638202 |
| NIBAN2 | niban apoptosis regulator 2 | 0.00637346 |
| PCM1 | pericentriolar material 1 | 0.0063172 |
| TMC5 | transmembrane channel-like 5 | 0.00629819 |
| GPATCH4 | G patch domain containing 4 | 0.00626423 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | 0.00614734 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00608629 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00605561 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.00598032 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00593266 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00589739 |
| SVIL | supervillin | 0.00588825 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.00588595 |
| RPS18 | ribosomal protein S18 | 0.00588118 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00587828 |
| CDK19 | cyclin-dependent kinase 19 | 0.00579214 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00577492 |
| TPM3 | tropomyosin 3 | 0.00576291 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00575944 |
| USP24 | ubiquitin specific peptidase 24 | 0.00573319 |
| ZNF148 | zinc finger protein 148 | 0.00570039 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00568976 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.00564386 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00563972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.220013 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.150886 |
| MT2A | metallothionein 2A | -0.105086 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0758424 |
| SQSTM1 | sequestosome 1 | -0.068984 |
| MTSS1 | metastasis suppressor 1 | -0.0656772 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0651137 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0586526 |
| RBM39 | RNA binding motif protein 39 | -0.0537832 |
| B2M | beta-2-microglobulin | -0.0482632 |
| PTMA | prothymosin, alpha | -0.0474902 |
| EGR1 | early growth response 1 | -0.0448552 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0438799 |
| SULF1 | sulfatase 1 | -0.0438232 |
| GNAS | GNAS complex locus | -0.0434631 |
| TXNIP | thioredoxin interacting protein | -0.0421443 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0399775 |
| MT1E | metallothionein 1E | -0.0397084 |
| POTEF | POTE ankyrin domain family, member F | -0.0393734 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0388866 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0387265 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0362468 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0362091 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.035548 |
| GOLGA4 | golgin A4 | -0.0355064 |
| HDAC9 | histone deacetylase 9 | -0.0345513 |
| KLF10 | Kruppel-like factor 10 | -0.0339756 |
| STC1 | stanniocalcin 1 | -0.0339011 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0330522 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0326756 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0323565 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321502 |
| TMSB10 | thymosin beta 10 | -0.031626 |
| RPS21 | ribosomal protein S21 | -0.0314926 |
| HLA-B | major histocompatibility complex, class I, B | -0.0311602 |
| PALLD | palladin, cytoskeletal associated protein | -0.0310826 |
| MT1G | metallothionein 1G | -0.0308543 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0307761 |
| FLNB | filamin B, beta | -0.0306891 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0305407 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0297164 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0296528 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0295118 |
| CALU | calumenin | -0.028975 |
| PODXL | podocalyxin-like | -0.0289647 |
| TOP1 | topoisomerase (DNA) I | -0.0287703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0277765 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0272551 |
| IGF2 | insulin-like growth factor 2 | -0.0272491 |
| FOXO1 | forkhead box O1 | -0.0264926 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0264392 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0262027 |
| HM13 | histocompatibility (minor) 13 | -0.0261481 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0242881 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0242129 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0241644 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0237688 |
| CLU | clusterin | -0.0230212 |
| S100A10 | S100 calcium binding protein A10 | -0.0227489 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0226005 |
| MT1X | metallothionein 1X | -0.0225619 |
| HLA-E | major histocompatibility complex, class I, E | -0.0224434 |
| LMNA | lamin A/C | -0.0221679 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0220647 |
| CLIC4 | chloride intracellular channel 4 | -0.0218885 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0217142 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0214669 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0212356 |
| SNX9 | sorting nexin 9 | -0.0211934 |
| IRF1 | interferon regulatory factor 1 | -0.0210574 |
| TMSB4X | thymosin beta 4, X-linked | -0.0207282 |
| PRRC2C | proline-rich coiled-coil 2C | -0.020566 |
| RPS24 | ribosomal protein S24 | -0.0202864 |
| RRBP1 | ribosome binding protein 1 | -0.0201693 |
| MORF4L2 | mortality factor 4 like 2 | -0.0199639 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0199065 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.019861 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0196728 |
| FNIP1 | folliculin interacting protein 1 | -0.0196547 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0195744 |
| RPLP2 | ribosomal protein, large, P2 | -0.0194713 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0194292 |
| COPA | coatomer protein complex, subunit alpha | -0.0194004 |
| HDLBP | high density lipoprotein binding protein | -0.019304 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0192541 |
| RPS25 | ribosomal protein S25 | -0.0192383 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0191783 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0191533 |
| NDRG1 | N-myc downstream regulated 1 | -0.0189424 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0187244 |
| ACTG1 | actin gamma 1 | -0.0186753 |
| KRT17 | keratin 17, type I | -0.0186248 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0184518 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0183018 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0182426 |
| RCOR1 | REST corepressor 1 | -0.0181235 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0179659 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0178523 |
| RPS13 | ribosomal protein S13 | -0.0177187 |
| IER2 | immediate early response 2 | -0.0176787 |
