| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0904708 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0731606 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0653048 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0621398 |
| INTS6 | integrator complex subunit 6 | 0.0495298 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0481279 |
| SQSTM1 | sequestosome 1 | 0.0465315 |
| KLF6 | Kruppel-like factor 6 | 0.0440343 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0415549 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0371261 |
| FOXO3 | forkhead box O3 | 0.0349795 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0346663 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0326384 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0323525 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0319987 |
| EZR | ezrin | 0.0312336 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0308512 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.030746 |
| KLF10 | Kruppel-like factor 10 | 0.0300968 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0296988 |
| H1-0 | H1.0 linker histone | 0.0282091 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0274744 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0273586 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0273453 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0251261 |
| JUN | jun proto-oncogene | 0.0249879 |
| ATF4 | activating transcription factor 4 | 0.0244158 |
| MYOF | myoferlin | 0.0237649 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0226716 |
| NABP1 | nucleic acid binding protein 1 | 0.0224341 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0222168 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.022192 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0220147 |
| PCNX2 | pecanex 2 | 0.0216543 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0213618 |
| DST | dystonin | 0.0208293 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0206949 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0206672 |
| RUNX1 | runt-related transcription factor 1 | 0.0205653 |
| RESF1 | retroelement silencing factor 1 | 0.0203965 |
| CCND1 | cyclin D1 | 0.0203377 |
| RASEF | RAS and EF-hand domain containing | 0.0200335 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0199828 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0195903 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0194148 |
| H3-3B | H3.3 histone B | 0.0193197 |
| PLK2 | polo-like kinase 2 | 0.0189825 |
| RIGI | RNA sensor RIG-I | 0.0188423 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0187917 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.018691 |
| OGA | O-GlcNAcase | 0.0184941 |
| KRT18 | keratin 18, type I | 0.0184484 |
| LMNA | lamin A/C | 0.0183132 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0180929 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0176397 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0174518 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0172141 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0171243 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0171002 |
| HOMER1 | homer scaffolding protein 1 | 0.0170056 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0169956 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0169823 |
| RPL35A | ribosomal protein L35a | 0.0168534 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0168259 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0167784 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0167706 |
| DSPP | dentin sialophosphoprotein | 0.0167069 |
| ARRDC4 | arrestin domain containing 4 | 0.0164512 |
| SHTN1 | shootin 1 | 0.0163671 |
| BRD2 | bromodomain containing 2 | 0.0163379 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0162385 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0160222 |
| ADM | adrenomedullin | 0.0160093 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0155847 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0154888 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0152675 |
| SATB2 | SATB homeobox 2 | 0.0151435 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0150649 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0148751 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0148664 |
| RPL9 | ribosomal protein L9 | 0.0144859 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0144778 |
| RYBP | RING1 and YY1 binding protein | 0.0144247 |
| KITLG | KIT ligand | 0.014328 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0141827 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0140455 |
| ZNF638 | zinc finger protein 638 | 0.0138548 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.0137468 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0137275 |
| FER | fer (fps/fes related) tyrosine kinase | 0.013693 |
| RPS27L | ribosomal protein S27-like | 0.0136828 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0136388 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0135407 |
| LAMA4 | laminin, alpha 4 | 0.0134808 |
| SON | SON DNA binding protein | 0.013468 |
| KIAA1217 | KIAA1217 | 0.0133224 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.013322 |
| SERTAD2 | SERTA domain containing 2 | 0.013188 |
| AHNAK | AHNAK nucleoprotein | 0.0131625 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.013092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.151952 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.126399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0953679 |
| FAT1 | FAT atypical cadherin 1 | -0.0896564 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0874482 |
| PTMA | prothymosin, alpha | -0.0854478 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0844115 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0779644 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0779465 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0719271 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0705719 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0628177 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.061119 |
| NPSR1 | neuropeptide S receptor 1 | -0.0601385 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0576716 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0551209 |
| TNS4 | tensin 4 | -0.052072 |
| GOLGA4 | golgin A4 | -0.0520613 |
| CADPS | Ca++-dependent secretion activator | -0.0472598 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0472448 |
| FLNB | filamin B, beta | -0.0455037 |
| MYO1E | myosin IE | -0.0430678 |
| PRELID2 | PRELI domain containing 2 | -0.0414338 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0411536 |
| MLEC | malectin | -0.0407216 |
| RNF145 | ring finger protein 145 | -0.0402963 |
| PIGR | polymeric immunoglobulin receptor | -0.0375093 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0374903 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.037427 |
| TRIM2 | tripartite motif containing 2 | -0.0372725 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0370438 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0361675 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0351448 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.033511 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0334306 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0333638 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.031778 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0316203 |
| NDRG1 | N-myc downstream regulated 1 | -0.0311077 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0302431 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0301808 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.029698 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0295898 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294908 |
| ITGA6 | integrin, alpha 6 | -0.0293936 |
| VMP1 | vacuole membrane protein 1 | -0.029162 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0291098 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0290879 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0288267 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283679 |
| CCNY | cyclin Y | -0.0281671 |
| PKP2 | plakophilin 2 | -0.0280182 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0276432 |
| COG5 | component of oligomeric golgi complex 5 | -0.0273814 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0272697 |
| SETD5 | SET domain containing 5 | -0.0271389 |
| CLTC | clathrin, heavy chain (Hc) | -0.027117 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270489 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0266951 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0262262 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0261759 |
| RNF43 | ring finger protein 43 | -0.0260754 |
| PRSS3 | protease, serine, 3 | -0.0260058 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0258196 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0257898 |
| ACTN4 | actinin, alpha 4 | -0.0257715 |
| PKM | pyruvate kinase, muscle | -0.0256136 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255907 |
| HDLBP | high density lipoprotein binding protein | -0.0255441 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0250337 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0247127 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0245707 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0243418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0241567 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0240417 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0238849 |
| EGR1 | early growth response 1 | -0.0237846 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0237781 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0236552 |
| RBM39 | RNA binding motif protein 39 | -0.023578 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0234467 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0233766 |
| TPD52 | tumor protein D52 | -0.0233668 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0230636 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0228909 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0228705 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0227353 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0226402 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0225646 |
| CANX | calnexin | -0.0222833 |
| MAP4 | microtubule-associated protein 4 | -0.0219957 |
| CDK13 | cyclin-dependent kinase 13 | -0.0218292 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0216589 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0215733 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.021534 |
| ABHD2 | abhydrolase domain containing 2 | -0.0215293 |
| SEC24D | SEC24 family member D | -0.021501 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0213666 |
| POF1B | premature ovarian failure, 1B | -0.0213397 |
