| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.252432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.164857 |
| STC1 | stanniocalcin 1 | 0.0915663 |
| HMGA2 | high mobility group AT-hook 2 | 0.0882449 |
| ANGPTL4 | angiopoietin-like 4 | 0.087899 |
| ADM | adrenomedullin | 0.0834262 |
| PKM | pyruvate kinase, muscle | 0.0799719 |
| HDAC9 | histone deacetylase 9 | 0.0777769 |
| TXNRD1 | thioredoxin reductase 1 | 0.0757444 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0755239 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0738664 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.069136 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0685675 |
| SQSTM1 | sequestosome 1 | 0.0649032 |
| NAV2 | neuron navigator 2 | 0.0628145 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0596085 |
| ENO1 | enolase 1, (alpha) | 0.0585697 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0578658 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0557926 |
| FOSL1 | FOS-like antigen 1 | 0.0504015 |
| RND3 | Rho family GTPase 3 | 0.0501438 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0500323 |
| RAI14 | retinoic acid induced 14 | 0.0498818 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0493209 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0490375 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0490113 |
| SNX9 | sorting nexin 9 | 0.0458809 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0446979 |
| SP100 | SP100 nuclear antigen | 0.0441557 |
| CDCP1 | CUB domain containing protein 1 | 0.0433837 |
| MCL1 | myeloid cell leukemia 1 | 0.042859 |
| IL6ST | interleukin 6 signal transducer | 0.0406006 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0405213 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0403239 |
| RPS12 | ribosomal protein S12 | 0.0402036 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0396083 |
| SERTAD2 | SERTA domain containing 2 | 0.0389966 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0389707 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0386166 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0380359 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0375225 |
| AHNAK | AHNAK nucleoprotein | 0.0375052 |
| THBS1 | thrombospondin 1 | 0.0374452 |
| IFI44L | interferon-induced protein 44-like | 0.0369698 |
| TMSB4X | thymosin beta 4, X-linked | 0.0361011 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0357963 |
| SKIL | SKI-like proto-oncogene | 0.0357072 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0352079 |
| NDRG1 | N-myc downstream regulated 1 | 0.0347716 |
| HMGA1 | high mobility group AT-hook 1 | 0.0346319 |
| PLIN2 | perilipin 2 | 0.0343944 |
| FRMD6 | FERM domain containing 6 | 0.0338721 |
| PTK2 | protein tyrosine kinase 2 | 0.0336409 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334154 |
| MYO10 | myosin X | 0.0331728 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0330776 |
| SYNJ2 | synaptojanin 2 | 0.032832 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0319385 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0317757 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0303734 |
| CEP250 | centrosomal protein 250kDa | 0.0302394 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0299037 |
| VEGFC | vascular endothelial growth factor C | 0.0297838 |
| PCBP2 | poly(rC) binding protein 2 | 0.0294721 |
| R3HDM2 | R3H domain containing 2 | 0.029414 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0293113 |
| LDHA | lactate dehydrogenase A | 0.0290784 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0290757 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0289098 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0286767 |
| DTNA | dystrobrevin, alpha | 0.0286467 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0281348 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0281332 |
| VEGFA | vascular endothelial growth factor A | 0.0279291 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0277965 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0276756 |
| MX1 | MX dynamin-like GTPase 1 | 0.0276335 |
| KLF6 | Kruppel-like factor 6 | 0.0273134 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0269911 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0267735 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0267132 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0266806 |
| AGO2 | argonaute RISC catalytic component 2 | 0.026398 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.0260785 |
| EMP1 | epithelial membrane protein 1 | 0.0259375 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0258032 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0257992 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0255955 |
| SECISBP2 | SECIS binding protein 2 | 0.0255521 |
| FAM107B | family with sequence similarity 107, member B | 0.0254697 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252802 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0252044 |
| MTSS1 | metastasis suppressor 1 | 0.0251576 |
| LRRC28 | leucine rich repeat containing 28 | 0.024915 |
| FOXL1 | forkhead box L1 | 0.0248867 |
| RPL9 | ribosomal protein L9 | 0.024605 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0245771 |
| NAV3 | neuron navigator 3 | 0.0244786 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0243108 |
| OTUD4 | OTU deubiquitinase 4 | 0.0242805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.187818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.175585 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.120183 |
| GOLGA4 | golgin A4 | -0.10671 |
| EGR1 | early growth response 1 | -0.0915339 |
| RBM39 | RNA binding motif protein 39 | -0.0872775 |
| GPC6 | glypican 6 | -0.0849884 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0704148 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0692551 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.066748 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0594757 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0588863 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.052901 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0526091 |
| SYT1 | synaptotagmin I | -0.0524259 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0519758 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0503502 |
| FN1 | fibronectin 1 | -0.0502623 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0500613 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0481469 |
| CALU | calumenin | -0.0473372 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0462206 |
| CANX | calnexin | -0.0457255 |
| HDLBP | high density lipoprotein binding protein | -0.0454941 |
| LOX | lysyl oxidase | -0.0452935 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0451124 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0433791 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0430918 |
| SPAG9 | sperm associated antigen 9 | -0.0403281 |
| COPA | coatomer protein complex, subunit alpha | -0.039381 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.039352 |
| FAM20C | family with sequence similarity 20, member C | -0.0385766 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0375183 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0373777 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0363338 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0360265 |
| SRP54 | signal recognition particle 54kDa | -0.0358154 |
| TMEM263 | transmembrane protein 263 | -0.0349968 |
| PRELID2 | PRELI domain containing 2 | -0.0347152 |
| SEC24D | SEC24 family member D | -0.0345436 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0344682 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0338463 |
| VIM | vimentin | -0.0336996 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0334054 |
| COG5 | component of oligomeric golgi complex 5 | -0.0331027 |
| LRRC49 | leucine rich repeat containing 49 | -0.0326954 |
| PDE4C | phosphodiesterase 4C, cAMP-specific | -0.0324686 |
| KLF10 | Kruppel-like factor 10 | -0.0324049 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0319117 |
| ETV6 | ets variant 6 | -0.0318362 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0318001 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0316562 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.0316272 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0309856 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0307889 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0307872 |
| TMSB10 | thymosin beta 10 | -0.0307181 |
| PTMA | prothymosin, alpha | -0.0304897 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0304887 |
| HM13 | histocompatibility (minor) 13 | -0.0304835 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0298126 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0297765 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.029663 |
| SETD5 | SET domain containing 5 | -0.0294991 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0294555 |
| VMP1 | vacuole membrane protein 1 | -0.02934 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.029261 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0290655 |
| SEPTIN2 | septin 2 | -0.0286618 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0281112 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0275971 |
| CALR | calreticulin | -0.0275658 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0273685 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0269974 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0269556 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0265655 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265139 |
| MYO9A | myosin IXA | -0.0264938 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0264657 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0263756 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0262135 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.0261972 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0261196 |
| IER2 | immediate early response 2 | -0.0259638 |
| MORF4L2 | mortality factor 4 like 2 | -0.0259257 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0254702 |
| FNIP1 | folliculin interacting protein 1 | -0.0254673 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0254434 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0254397 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0252541 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0251879 |
| GOLGA3 | golgin A3 | -0.0251599 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.025002 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0249925 |
| SBF2 | SET binding factor 2 | -0.02497 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0247576 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247446 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0245785 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0242474 |
| CLIC4 | chloride intracellular channel 4 | -0.0238426 |
