| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Homoharringtonine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.131615 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0877466 |
| TXNRD1 | thioredoxin reductase 1 | 0.0841922 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.074618 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0717593 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0601088 |
| TPM3 | tropomyosin 3 | 0.0575196 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0561535 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.050665 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0496966 |
| DST | dystonin | 0.046606 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0399699 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0356097 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0355816 |
| WWOX | WW domain containing oxidoreductase | 0.0345489 |
| CALD1 | caldesmon 1 | 0.0340423 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0337613 |
| BRD2 | bromodomain containing 2 | 0.0333976 |
| MCL1 | myeloid cell leukemia 1 | 0.0326262 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0323602 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0318246 |
| AHNAK | AHNAK nucleoprotein | 0.0316887 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0309508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0293925 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0284717 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0279403 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0278345 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0272586 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0269955 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0261032 |
| ZNF462 | zinc finger protein 462 | 0.0254469 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0254106 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.025078 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.0249105 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0244473 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0243985 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0238517 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0234553 |
| FAT1 | FAT atypical cadherin 1 | 0.0232477 |
| FOSL1 | FOS-like antigen 1 | 0.0231032 |
| SQSTM1 | sequestosome 1 | 0.0230323 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0218915 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.021324 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0212845 |
| SVIL | supervillin | 0.0212175 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0208568 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0206854 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0206825 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0203019 |
| GLO1 | glyoxalase I | 0.0201379 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0197924 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.019729 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0195783 |
| PRELID2 | PRELI domain containing 2 | 0.0192352 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0192293 |
| GPC5 | glypican 5 | 0.0191653 |
| DTNA | dystrobrevin, alpha | 0.0189325 |
| MSH6 | mutS homolog 6 | 0.0188657 |
| PKM | pyruvate kinase, muscle | 0.0186687 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0184897 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0183157 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0182024 |
| NOTCH2 | notch 2 | 0.0181543 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0181501 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0181061 |
| LRRC58 | leucine rich repeat containing 58 | 0.0180414 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0178723 |
| CORO1C | coronin, actin binding protein, 1C | 0.0177782 |
| STYK1 | serine/threonine/tyrosine kinase 1 | 0.0177733 |
| LEKR1 | leucine, glutamate and lysine rich 1 | 0.0175553 |
| GPATCH4 | G patch domain containing 4 | 0.0171803 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 0.0171397 |
| HOMER1 | homer scaffolding protein 1 | 0.0170666 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0169961 |
| FHIT | fragile histidine triad | 0.0169958 |
| ANO6 | anoctamin 6 | 0.0169851 |
| RAD51B | RAD51 paralog B | 0.0167623 |
| RANBP2 | RAN binding protein 2 | 0.0166807 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0166377 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0163889 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.016338 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0163287 |
| SRPK1 | SRSF protein kinase 1 | 0.0163101 |
| ANXA5 | annexin A5 | 0.0161018 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0159547 |
| GPR50 | G protein-coupled receptor 50 | 0.0158836 |
| RIMOC1 | RAB7A interacting MON1-CCZ1 complex subunit 1 | 0.0158037 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0154853 |
| CPNE1 | copine I | 0.0153545 |
| CBX5 | chromobox homolog 5 | 0.0153207 |
| CEP250 | centrosomal protein 250kDa | 0.0152128 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0150163 |
| KRT18 | keratin 18, type I | 0.014979 |
| CDV3 | CDV3 homolog (mouse) | 0.0148885 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.0148849 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0148201 |
| TRAF1 | TNF receptor-associated factor 1 | 0.0146067 |
| AEBP2 | AE binding protein 2 | 0.014583 |
| MYO6 | myosin VI | 0.0144291 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0143337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23857 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127932 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125306 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0844633 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0786755 |
| TMSB10 | thymosin beta 10 | -0.0668555 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0666838 |
| RBM39 | RNA binding motif protein 39 | -0.0659878 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0603716 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0515224 |
| GNAS | GNAS complex locus | -0.0509495 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0497389 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0473534 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0462651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0456198 |
| HMGA2 | high mobility group AT-hook 2 | -0.0437009 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0436685 |
| PTMA | prothymosin, alpha | -0.0433456 |
| FBXO11 | F-box protein 11 | -0.0431101 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0419448 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0415877 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0410327 |
| RPL12 | ribosomal protein L12 | -0.0394061 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0382191 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0379335 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0371405 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0369682 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0363425 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0358503 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0352028 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0351019 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0349811 |
| RPLP0 | ribosomal protein, large, P0 | -0.0348891 |
| CAVIN1 | caveolae associated protein 1 | -0.0346724 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0346329 |
| RACK1 | receptor for activated C kinase 1 | -0.034554 |
| TMEM41B | transmembrane protein 41B | -0.0342584 |
| LMNA | lamin A/C | -0.0341819 |
| COPA | coatomer protein complex, subunit alpha | -0.0339856 |
| EHBP1 | EH domain binding protein 1 | -0.0337537 |
| RPL37 | ribosomal protein L37 | -0.0337426 |
| GOLGA4 | golgin A4 | -0.0336144 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0335623 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0333384 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.032834 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0323804 |
| RPLP1 | ribosomal protein, large, P1 | -0.032031 |
| ACTG1 | actin gamma 1 | -0.0316984 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0313883 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0309724 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0306567 |
| GOLGB1 | golgin B1 | -0.0306271 |
| PHIP | pleckstrin homology domain interacting protein | -0.0304865 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0303432 |
| VIM | vimentin | -0.0300344 |
| GRAMD1B | GRAM domain containing 1B | -0.0299426 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0296115 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0290228 |
| DENND5B | DENN/MADD domain containing 5B | -0.0287845 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0286957 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0282649 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0280869 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0280576 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0278775 |
| RPS8 | ribosomal protein S8 | -0.0278051 |
| UBC | ubiquitin C | -0.0274006 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0273863 |
| ATXN2 | ataxin 2 | -0.0273015 |
| VMP1 | vacuole membrane protein 1 | -0.0272369 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0263383 |
| EGR1 | early growth response 1 | -0.0262127 |
| NBEAL1 | neurobeachin-like 1 | -0.026163 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0260979 |
| RPS27 | ribosomal protein S27 | -0.0259617 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0258118 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0257166 |
| BPTF | bromodomain PHD finger transcription factor | -0.0255915 |
| WASF2 | WAS protein family, member 2 | -0.0253549 |
| RTN4 | reticulon 4 | -0.0252752 |
| UBB | ubiquitin B | -0.0252316 |
| RPL34 | ribosomal protein L34 | -0.0251831 |
| FTL | ferritin, light polypeptide | -0.0249586 |
| THOC2 | THO complex 2 | -0.024901 |
| RPS3 | ribosomal protein S3 | -0.0248981 |
| EPN2 | epsin 2 | -0.0248653 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0248479 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0247655 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0247544 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0247432 |
| RPL32 | ribosomal protein L32 | -0.0243122 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0242722 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0242325 |
| RPS19 | ribosomal protein S19 | -0.0241642 |
| TLN1 | talin 1 | -0.0240862 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0239984 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0239928 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0239108 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.023891 |
| CALR | calreticulin | -0.0238089 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0237862 |
