| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Homoharringtonine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.10867 |
| AHNAK | AHNAK nucleoprotein | 0.106171 |
| SQSTM1 | sequestosome 1 | 0.0941706 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0899599 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0782175 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0770066 |
| LAMB3 | laminin, beta 3 | 0.0650752 |
| STEAP4 | STEAP family member 4 | 0.0645288 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0642623 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0636706 |
| ADM | adrenomedullin | 0.0616151 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0584537 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.05554 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0541478 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0531779 |
| PLEC | plectin | 0.0529402 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.05208 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0513867 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0498397 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0485066 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0450711 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0445983 |
| DST | dystonin | 0.04313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.042722 |
| MCL1 | myeloid cell leukemia 1 | 0.042387 |
| FHIT | fragile histidine triad | 0.0414913 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0405463 |
| RNF213 | ring finger protein 213 | 0.0395748 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0385082 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0383857 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0381378 |
| G0S2 | G0/G1 switch 2 | 0.0380139 |
| RAD51B | RAD51 paralog B | 0.0377923 |
| H3-3B | H3.3 histone B | 0.0371596 |
| GOLGB1 | golgin B1 | 0.0370027 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0368224 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0368003 |
| ENO1 | enolase 1, (alpha) | 0.0364818 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0364453 |
| KLF6 | Kruppel-like factor 6 | 0.0363561 |
| RND3 | Rho family GTPase 3 | 0.0348602 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0348177 |
| CENPF | centromere protein F, 350/400kDa | 0.0346171 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0344478 |
| ADAR | adenosine deaminase, RNA-specific | 0.0339722 |
| ARRDC3 | arrestin domain containing 3 | 0.0337337 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0332311 |
| HDAC9 | histone deacetylase 9 | 0.0331513 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331006 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.032764 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0324677 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0324174 |
| DTNA | dystrobrevin, alpha | 0.031818 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0313997 |
| PHF3 | PHD finger protein 3 | 0.031387 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0310067 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0309699 |
| CD47 | CD47 molecule | 0.0302588 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0300953 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0292941 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0290142 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0284009 |
| MX1 | MX dynamin-like GTPase 1 | 0.0279121 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0278156 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0274647 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0274434 |
| VEGFA | vascular endothelial growth factor A | 0.0274198 |
| RIGI | RNA sensor RIG-I | 0.0273961 |
| BBX | bobby sox homolog (Drosophila) | 0.0270423 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0269994 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0268416 |
| IL6ST | interleukin 6 signal transducer | 0.0266473 |
| PLIN2 | perilipin 2 | 0.0262451 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0254889 |
| DUSP6 | dual specificity phosphatase 6 | 0.0254444 |
| H1-0 | H1.0 linker histone | 0.0254231 |
| TUFT1 | tuftelin 1 | 0.0253446 |
| CEP350 | centrosomal protein 350kDa | 0.025282 |
| REST | RE1-silencing transcription factor | 0.0250469 |
| WWC1 | WW and C2 domain containing 1 | 0.0247513 |
| RYBP | RING1 and YY1 binding protein | 0.0247316 |
| RSF1 | remodeling and spacing factor 1 | 0.0247277 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0244317 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0244247 |
| AHR | aryl hydrocarbon receptor | 0.0242472 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0239727 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.023906 |
| APOL6 | apolipoprotein L, 6 | 0.0237312 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0235264 |
| FBXO32 | F-box protein 32 | 0.0228871 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0223887 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0220854 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0219039 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.021821 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0213697 |
| UPP1 | uridine phosphorylase 1 | 0.0211897 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0208825 |
| XPO1 | exportin 1 | 0.0208346 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0206496 |
| KRT19 | keratin 19, type I | 0.0205825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.232324 |
| ASPH | aspartate beta-hydroxylase | -0.167813 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13175 |
| PTMA | prothymosin, alpha | -0.125935 |
| FN1 | fibronectin 1 | -0.116351 |
| TMSB10 | thymosin beta 10 | -0.105637 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0953494 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0908569 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0798287 |
| ACTG1 | actin gamma 1 | -0.0784284 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0774447 |
| CALU | calumenin | -0.0700981 |
| COPA | coatomer protein complex, subunit alpha | -0.0699034 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0680308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.065909 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.063101 |
| POTEF | POTE ankyrin domain family, member F | -0.0613974 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0590613 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0582439 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0573765 |
| FTL | ferritin, light polypeptide | -0.0549858 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0542886 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0531366 |
| S100A6 | S100 calcium binding protein A6 | -0.0529216 |
| GNAS | GNAS complex locus | -0.0511232 |
| SEC24D | SEC24 family member D | -0.0509961 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0493479 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.049007 |
| TMEM263 | transmembrane protein 263 | -0.0489949 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.048764 |
| TFG | TRK-fused gene | -0.0481293 |
| FAM3C | family with sequence similarity 3, member C | -0.0475358 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0469047 |
| UBC | ubiquitin C | -0.0466974 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.046179 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0460375 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0459236 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0451632 |
| LMO7 | LIM domain 7 | -0.045144 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0450261 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0438565 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0434133 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0430051 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0430026 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0420781 |
| EPCAM | epithelial cell adhesion molecule | -0.0419439 |
| AREG | amphiregulin | -0.0413882 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0406541 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0403516 |
| RNF145 | ring finger protein 145 | -0.0401674 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0396733 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0396704 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0396367 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0357949 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0357687 |
| GOLGA4 | golgin A4 | -0.035672 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0350698 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0349673 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0347596 |
| CALR | calreticulin | -0.0346647 |
| WASF2 | WAS protein family, member 2 | -0.0340745 |
| CCND1 | cyclin D1 | -0.0326778 |
| MYO6 | myosin VI | -0.0322983 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0320435 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0319127 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0319077 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.031678 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0315703 |
| RCOR1 | REST corepressor 1 | -0.0315508 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0312513 |
| CD109 | CD109 molecule | -0.0311863 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0310239 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0306853 |
| EGR1 | early growth response 1 | -0.0304643 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0304103 |
| CLINT1 | clathrin interactor 1 | -0.030001 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0298627 |
| ARF1 | ADP-ribosylation factor 1 | -0.029644 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0293078 |
| KLF10 | Kruppel-like factor 10 | -0.0291995 |
| MXD1 | MAX dimerization protein 1 | -0.0290499 |
| HDLBP | high density lipoprotein binding protein | -0.0290483 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.02873 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0287183 |
| TMEM39A | transmembrane protein 39A | -0.0286598 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0285869 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0284116 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0284064 |
| RBM39 | RNA binding motif protein 39 | -0.0284055 |
| SETD5 | SET domain containing 5 | -0.0283613 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0277115 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0275823 |
| HMGA1 | high mobility group AT-hook 1 | -0.027512 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0272223 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0271509 |
| CCNI | cyclin I | -0.0271295 |
| PTK2 | protein tyrosine kinase 2 | -0.0269542 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0269058 |
| TOP1 | topoisomerase (DNA) I | -0.0266197 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0265356 |
