| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB4 | phospholipase C, beta 4 | 0.173995 |
| CREB5 | cAMP responsive element binding protein 5 | 0.153328 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.126592 |
| HDAC9 | histone deacetylase 9 | 0.124546 |
| TXNRD1 | thioredoxin reductase 1 | 0.115566 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.115293 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.113239 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.106522 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.105338 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0995236 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0903033 |
| SPAG9 | sperm associated antigen 9 | 0.0860552 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0847859 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0816808 |
| RIGI | RNA sensor RIG-I | 0.0812074 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0778122 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0761732 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0746239 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0733999 |
| FNIP1 | folliculin interacting protein 1 | 0.0721662 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0706199 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0675681 |
| SQSTM1 | sequestosome 1 | 0.0640575 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.061276 |
| INHBA | inhibin, beta A | 0.060841 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0596599 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0590706 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0588995 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.054741 |
| FOSL1 | FOS-like antigen 1 | 0.0543669 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0541506 |
| RGS2 | regulator of G-protein signaling 2 | 0.0524958 |
| NBEAL1 | neurobeachin-like 1 | 0.0497709 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0496484 |
| DMD | dystrophin | 0.0490206 |
| JUN | jun proto-oncogene | 0.046788 |
| FAT1 | FAT atypical cadherin 1 | 0.0447341 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.044533 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0425704 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.0423347 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0416557 |
| MYO10 | myosin X | 0.0414229 |
| NOCT | nocturnin | 0.0414151 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0411105 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0408891 |
| VIM | vimentin | 0.040227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0400073 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0392683 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0386505 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0380953 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.03787 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0377104 |
| LYST | lysosomal trafficking regulator | 0.0376396 |
| KYNU | kynureninase | 0.0375925 |
| AEBP2 | AE binding protein 2 | 0.037193 |
| ATF3 | activating transcription factor 3 | 0.0371383 |
| PLK2 | polo-like kinase 2 | 0.0369014 |
| RASAL2 | RAS protein activator like 2 | 0.0362161 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0361052 |
| TBXT | T-box transcription factor T | 0.0351255 |
| RPL37A | ribosomal protein L37a | 0.0350355 |
| MYPN | myopalladin | 0.0346226 |
| ETV3 | ets variant 3 | 0.0340607 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0337385 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0336886 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0336867 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0329702 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0328908 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0321974 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0321434 |
| HOMER1 | homer scaffolding protein 1 | 0.0317245 |
| LSAMP | limbic system-associated membrane protein | 0.0316345 |
| DUSP10 | dual specificity phosphatase 10 | 0.0312384 |
| NAV3 | neuron navigator 3 | 0.0307099 |
| RPL31 | ribosomal protein L31 | 0.0298707 |
| GLMN | glomulin, FKBP associated protein | 0.0296825 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0292001 |
| SOCS3 | suppressor of cytokine signaling 3 | 0.0291065 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0289341 |
| CTSL | cathepsin L | 0.0287201 |
| STC1 | stanniocalcin 1 | 0.0285146 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0285013 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0282697 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0277627 |
| RHOB | ras homolog family member B | 0.027579 |
| INTS6 | integrator complex subunit 6 | 0.0275585 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0274028 |
| IFI44 | interferon-induced protein 44 | 0.0273436 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.027319 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0271151 |
| FOSL2 | FOS-like antigen 2 | 0.0269595 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0263882 |
| RPLP1 | ribosomal protein, large, P1 | 0.0261869 |
| PER1 | period circadian clock 1 | 0.026069 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0260643 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0259479 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.025947 |
| ZFP36 | ZFP36 ring finger protein | 0.0257532 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0256381 |
| MAP7 | microtubule-associated protein 7 | 0.0251266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.277134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164111 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.138893 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129435 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.112254 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.104072 |
| ASPH | aspartate beta-hydroxylase | -0.0967099 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0945378 |
| MT2A | metallothionein 2A | -0.0929325 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0828179 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0752974 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0752868 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0676062 |
| GDA | guanine deaminase | -0.0606056 |
| NRCAM | neuronal cell adhesion molecule | -0.0575649 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0567353 |
| FN1 | fibronectin 1 | -0.0562818 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0520112 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0492505 |
| COL5A2 | collagen, type V, alpha 2 | -0.0476566 |
| NEK7 | NIMA-related kinase 7 | -0.0476302 |
| GRAMD1B | GRAM domain containing 1B | -0.0460894 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0448894 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0447626 |
| FLNB | filamin B, beta | -0.0437952 |
| CANX | calnexin | -0.0437267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0435795 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0432069 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.042417 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.041871 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0411707 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0406814 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0354904 |
| SMYD3 | SET and MYND domain containing 3 | -0.0352991 |
| RBM39 | RNA binding motif protein 39 | -0.0349436 |
| FAM13A | family with sequence similarity 13, member A | -0.0348929 |
| PYGL | phosphorylase, glycogen, liver | -0.0346361 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342563 |
| PCBP3 | poly(rC) binding protein 3 | -0.0332726 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0332349 |
| RTN4 | reticulon 4 | -0.0331105 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0314491 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0311994 |
| MFF | mitochondrial fission factor | -0.0310766 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0309068 |
| COPA | coatomer protein complex, subunit alpha | -0.0302714 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0302225 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0300014 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0299985 |
| PDE10A | phosphodiesterase 10A | -0.0299877 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.02943 |
| NBAS | neuroblastoma amplified sequence | -0.0283039 |
| CTSC | cathepsin C | -0.0281669 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0277234 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0273173 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.026928 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0258027 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256495 |
| TPD52 | tumor protein D52 | -0.0256483 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0254844 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0253514 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0251672 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0251004 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0247366 |
| GPC6 | glypican 6 | -0.0244988 |
| COG5 | component of oligomeric golgi complex 5 | -0.0242468 |
| UBC | ubiquitin C | -0.0241419 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0236993 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0236385 |
| MAP1B | microtubule-associated protein 1B | -0.0235064 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0230687 |
| CENPF | centromere protein F, 350/400kDa | -0.0229654 |
| CALU | calumenin | -0.0228069 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0227944 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0225698 |
| HELZ | helicase with zinc finger | -0.0224093 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0223987 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0219769 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0214892 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0213862 |
| OSMR | oncostatin M receptor | -0.0213051 |
| PHF21A | PHD finger protein 21A | -0.0211485 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0209117 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0208066 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0206888 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206372 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0205462 |
| GLIS3 | GLIS family zinc finger 3 | -0.0204599 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0204437 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0203844 |
| ANXA1 | annexin A1 | -0.0202268 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0200735 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0198282 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0197478 |
| MYOF | myoferlin | -0.0197091 |
| TXNIP | thioredoxin interacting protein | -0.0196998 |
| RTN1 | reticulon 1 | -0.0195098 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0193662 |
| TNPO1 | transportin 1 | -0.01928 |
| DIAPH2 | diaphanous-related formin 2 | -0.019273 |
