| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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124 genes differentially expressed following the Homoharringtonine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.285365 |
| SQSTM1 | sequestosome 1 | 0.176092 |
| LSAMP | limbic system-associated membrane protein | 0.175044 |
| FAT1 | FAT atypical cadherin 1 | 0.160433 |
| AHNAK | AHNAK nucleoprotein | 0.11529 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.107744 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.107537 |
| TXNRD1 | thioredoxin reductase 1 | 0.10533 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.10445 |
| MT2A | metallothionein 2A | 0.101764 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.101487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.100043 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0900768 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0896781 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0885895 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0871802 |
| ENO1 | enolase 1, (alpha) | 0.0831609 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0823431 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0812072 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0711981 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0708824 |
| FNIP1 | folliculin interacting protein 1 | 0.070164 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0602943 |
| GOLGA4 | golgin A4 | 0.0600848 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0597025 |
| H3-3B | H3.3 histone B | 0.0515619 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0491763 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0479752 |
| RBM39 | RNA binding motif protein 39 | 0.0477004 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0457626 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0419723 |
| FOXO3 | forkhead box O3 | 0.0403421 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0396275 |
| SKIL | SKI-like proto-oncogene | 0.0388946 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0388526 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0375542 |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) | 0.0366786 |
| HDAC9 | histone deacetylase 9 | 0.0358379 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0313669 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0295311 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0273482 |
| BPTF | bromodomain PHD finger transcription factor | 0.026235 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0237125 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0234888 |
| EYS | eyes shut homolog (Drosophila) | 0.0233201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0187731 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.015787 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0143716 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0128501 |
| ATF3 | activating transcription factor 3 | 0.0127705 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00903009 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.00765834 |
| NRG3 | neuregulin 3 | 0.00757283 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00697937 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00616408 |
| SPAG9 | sperm associated antigen 9 | 0.00344019 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00304772 |
| VIM | vimentin | 0.00303042 |
| PDE10A | phosphodiesterase 10A | 6.35413E-4 |
| IER2 | immediate early response 2 | 4.82435E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.206652 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18868 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.159949 |
| EFNA5 | ephrin-A5 | -0.14236 |
| EGR1 | early growth response 1 | -0.137839 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.127433 |
| ASPH | aspartate beta-hydroxylase | -0.120632 |
| GPC6 | glypican 6 | -0.0987834 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0958887 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0910779 |
| UBC | ubiquitin C | -0.0851263 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.084972 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0764852 |
| VCL | vinculin | -0.0730407 |
| RTN4 | reticulon 4 | -0.0716451 |
| IGF2 | insulin-like growth factor 2 | -0.0695229 |
| FN1 | fibronectin 1 | -0.0690383 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0644335 |
| PRKCA | protein kinase C, alpha | -0.0637819 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0637132 |
| MYO1E | myosin IE | -0.0599755 |
| SMYD3 | SET and MYND domain containing 3 | -0.0577709 |
| RPS3 | ribosomal protein S3 | -0.0576142 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0548245 |
| RPL23 | ribosomal protein L23 | -0.0505633 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0494342 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0490097 |
| CCNL1 | cyclin L1 | -0.0473876 |
| EGFR | epidermal growth factor receptor | -0.0442331 |
| HDLBP | high density lipoprotein binding protein | -0.0439596 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0432516 |
| ACTN4 | actinin, alpha 4 | -0.0429565 |
| DST | dystonin | -0.0411517 |
| GPHN | gephyrin | -0.0397761 |
| TXNIP | thioredoxin interacting protein | -0.0389997 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.037682 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0376393 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0362133 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0359829 |
| CDH13 | cadherin 13 | -0.0359133 |
| ATF6 | activating transcription factor 6 | -0.0357361 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0356438 |
| LDHA | lactate dehydrogenase A | -0.0348578 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0325979 |
| ZNF292 | zinc finger protein 292 | -0.029631 |
| ANXA2 | annexin A2 | -0.0268696 |
| VGF | VGF nerve growth factor inducible | -0.0214771 |
| ATXN1 | ataxin 1 | -0.0200504 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0196865 |
| JUN | jun proto-oncogene | -0.0192793 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0192091 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0182875 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0139165 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0124357 |
| NUP58 | nucleoporin 58 | -0.0108384 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00923439 |
| RORA | RAR-related orphan receptor A | -0.00877911 |
| PGK1 | phosphoglycerate kinase 1 | -0.0067408 |
| KLF10 | Kruppel-like factor 10 | -0.00649398 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.00450787 |
| MCL1 | myeloid cell leukemia 1 | -0.00367334 |
| SETD5 | SET domain containing 5 | -0.00270152 |
| GLMN | glomulin, FKBP associated protein | -0.00158802 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00152702 |
