| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.12938 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0836268 |
| ZFP30 | ZFP30 zinc finger protein | 0.0795654 |
| DST | dystonin | 0.0744433 |
| PHIP | pleckstrin homology domain interacting protein | 0.0689321 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0646803 |
| ZNF217 | zinc finger protein 217 | 0.0630756 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0619884 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0591303 |
| XPO1 | exportin 1 | 0.0557131 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0552472 |
| HDAC9 | histone deacetylase 9 | 0.0547534 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0537629 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.053615 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.052964 |
| UTRN | utrophin | 0.0515025 |
| ZNF608 | zinc finger protein 608 | 0.0496581 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0492585 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0482334 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0458744 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0454973 |
| NFIB | nuclear factor I/B | 0.0439112 |
| NHSL1 | NHS-like 1 | 0.0432534 |
| OGA | O-GlcNAcase | 0.0431622 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0426516 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.040336 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0403196 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0381672 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0377547 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.037513 |
| SON | SON DNA binding protein | 0.0371081 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0366788 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.03664 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0364456 |
| NFIA | nuclear factor I/A | 0.0363123 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0357144 |
| BNC2 | basonuclin 2 | 0.0356467 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0353341 |
| GPHN | gephyrin | 0.035322 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0351543 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0350479 |
| MEF2C | myocyte enhancer factor 2C | 0.0349252 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0348336 |
| HMGA2 | high mobility group AT-hook 2 | 0.0347993 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0336747 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0333628 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0325911 |
| SKIL | SKI-like proto-oncogene | 0.0325645 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0318003 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0316331 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0314561 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311107 |
| USP34 | ubiquitin specific peptidase 34 | 0.0307334 |
| CEP135 | centrosomal protein 135kDa | 0.0303566 |
| PHF3 | PHD finger protein 3 | 0.029934 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0298641 |
| DMXL2 | Dmx-like 2 | 0.0292618 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0291446 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0290833 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0286636 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0284739 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0284414 |
| UBN2 | ubinuclein 2 | 0.0284366 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0283194 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0280398 |
| JMJD1C | jumonji domain containing 1C | 0.0279082 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0277569 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | 0.027593 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0275761 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0274811 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0270165 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0267758 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0266739 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0265071 |
| ZNF638 | zinc finger protein 638 | 0.0257763 |
| MED13 | mediator complex subunit 13 | 0.0250598 |
| R3HDM2 | R3H domain containing 2 | 0.0250537 |
| YAP1 | Yes-associated protein 1 | 0.0248739 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0247517 |
| BPTF | bromodomain PHD finger transcription factor | 0.0247272 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246418 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0244163 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0243827 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0242453 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0242159 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0239146 |
| PER1 | period circadian clock 1 | 0.023845 |
| MGA | MGA, MAX dimerization protein | 0.0236978 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0236504 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0235239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0235143 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.023513 |
| SQSTM1 | sequestosome 1 | 0.0235075 |
| RREB1 | ras responsive element binding protein 1 | 0.0234595 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0234523 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0234168 |
| REST | RE1-silencing transcription factor | 0.0233675 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0233145 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0232019 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.0231778 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.244325 |
| GPC3 | glypican 3 | -0.123103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109692 |
| COL11A1 | collagen, type XI, alpha 1 | -0.109161 |
| VIM | vimentin | -0.0990854 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0926791 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0899945 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0884594 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0828088 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.08165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.076587 |
| PCDH9 | protocadherin 9 | -0.0750396 |
| COL1A2 | collagen, type I, alpha 2 | -0.072659 |
| COL3A1 | collagen, type III, alpha 1 | -0.0693731 |
| CENPE | centromere protein E, 312kDa | -0.0678605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0672839 |
| PTMA | prothymosin, alpha | -0.0672353 |
| PEG10 | paternally expressed 10 | -0.0642694 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0621946 |
| CALU | calumenin | -0.057697 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0554727 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0538565 |
| GNAS | GNAS complex locus | -0.0488713 |
| NTM | neurotrimin | -0.0460279 |
| TMSB10 | thymosin beta 10 | -0.0457564 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0452532 |
| CALR | calreticulin | -0.0450628 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0450404 |
| RPS16 | ribosomal protein S16 | -0.0435303 |
| ACTG1 | actin gamma 1 | -0.0433347 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.043013 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0421068 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0413631 |
| CENPF | centromere protein F, 350/400kDa | -0.0408074 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0407383 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403272 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0398843 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0395258 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.039171 |
| MAP4 | microtubule-associated protein 4 | -0.0382268 |
| MT2A | metallothionein 2A | -0.0372165 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0362325 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0361418 |
| CDH19 | cadherin 19, type 2 | -0.0359414 |
| RPLP0 | ribosomal protein, large, P0 | -0.0357951 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0355832 |
| RPS8 | ribosomal protein S8 | -0.0354887 |
| PRELID2 | PRELI domain containing 2 | -0.035487 |
| CXADR | coxsackie virus and adenovirus receptor | -0.035317 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0343753 |
| RAI1 | retinoic acid induced 1 | -0.0332185 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0332042 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0324231 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324207 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0320534 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0316859 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0313369 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0312577 |
| RFPL4B | ret finger protein-like 4B | -0.0312404 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0311052 |
| FST | follistatin | -0.0308545 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0308527 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0306955 |
| HMGB2 | high mobility group box 2 | -0.0303767 |
| RTN4 | reticulon 4 | -0.0303318 |
| ARF1 | ADP-ribosylation factor 1 | -0.0301239 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0299722 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0292866 |
| THBS1 | thrombospondin 1 | -0.029019 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0283572 |
| TPX2 | TPX2, microtubule-associated | -0.0283127 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0282545 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0281295 |
| MED12L | mediator complex subunit 12-like | -0.0277834 |
| TMSB4X | thymosin beta 4, X-linked | -0.027504 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0274474 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0271409 |
| MKI67 | marker of proliferation Ki-67 | -0.0269954 |
| ZNF385D | zinc finger protein 385D | -0.0267125 |
| URI1 | URI1, prefoldin-like chaperone | -0.0267036 |
| RPL12 | ribosomal protein L12 | -0.0265775 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265247 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262392 |
| RPL4 | ribosomal protein L4 | -0.026236 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0260227 |
| QKI | QKI, KH domain containing, RNA binding | -0.0259716 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0259375 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0256248 |
| RPS2 | ribosomal protein S2 | -0.0255937 |
| PCDH17 | protocadherin 17 | -0.025496 |
| SGO2 | shugoshin 2 | -0.025215 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0252118 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.025208 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0249425 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0247771 |
| RPL11 | ribosomal protein L11 | -0.0246221 |
| TUBB | tubulin, beta class I | -0.0245835 |
| RPLP1 | ribosomal protein, large, P1 | -0.0245493 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0244372 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0242716 |
