| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Homoharringtonine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Homoharringtonine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO1 | enolase 1, (alpha) | 0.145211 |
| HDAC9 | histone deacetylase 9 | 0.134395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0769301 |
| ADM | adrenomedullin | 0.0701808 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0697291 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0683033 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0614841 |
| IL6ST | interleukin 6 signal transducer | 0.0596572 |
| AHR | aryl hydrocarbon receptor | 0.0552703 |
| COL1A1 | collagen, type I, alpha 1 | 0.0517539 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0485938 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0483298 |
| ZNF395 | zinc finger protein 395 | 0.0454281 |
| DST | dystonin | 0.0433877 |
| S100A9 | S100 calcium binding protein A9 | 0.0426795 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0416285 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.0409786 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0408783 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0404378 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.039192 |
| ARRDC3 | arrestin domain containing 3 | 0.038655 |
| KYNU | kynureninase | 0.0385532 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0383195 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0379117 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0376285 |
| CADM1 | cell adhesion molecule 1 | 0.0366191 |
| TMSB10 | thymosin beta 10 | 0.0362637 |
| ACTG1 | actin gamma 1 | 0.0356727 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0355434 |
| SEPTIN7 | septin 7 | 0.0347719 |
| LAMB3 | laminin, beta 3 | 0.0344329 |
| FLNA | filamin A, alpha | 0.034383 |
| CDK6 | cyclin-dependent kinase 6 | 0.0339989 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0339148 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0335987 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0333847 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0322369 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0316468 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0312996 |
| EGR1 | early growth response 1 | 0.0312225 |
| RPL7 | ribosomal protein L7 | 0.0305656 |
| TET3 | tet methylcytosine dioxygenase 3 | 0.0302639 |
| THBS1 | thrombospondin 1 | 0.0301303 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297592 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0297472 |
| RPL37A | ribosomal protein L37a | 0.0296958 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0296186 |
| BBX | bobby sox homolog (Drosophila) | 0.0291825 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0290868 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0290549 |
| UVRAG | UV radiation resistance associated | 0.0288735 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0288692 |
| ANGPTL4 | angiopoietin-like 4 | 0.0284952 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0277823 |
| PKM | pyruvate kinase, muscle | 0.0277271 |
| PLCB4 | phospholipase C, beta 4 | 0.0272713 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0272656 |
| FMN1 | formin 1 | 0.0272339 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0269881 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0269194 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.026868 |
| PHF21A | PHD finger protein 21A | 0.0267916 |
| PATL2 | protein associated with topoisomerase II homolog 2 (yeast) | 0.0266916 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0262863 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0262737 |
| MT2A | metallothionein 2A | 0.0262525 |
| CD83 | CD83 molecule | 0.0260637 |
| ZNF638 | zinc finger protein 638 | 0.0259296 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0259259 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.025895 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0258905 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0257323 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.025706 |
| ATG10 | autophagy related 10 | 0.0256887 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0256606 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0256594 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0251364 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.024639 |
| SEC61G | Sec61 gamma subunit | 0.024478 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243677 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0238976 |
| ERBIN | erbb2 interacting protein | 0.0238533 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0238116 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0232702 |
| LYST | lysosomal trafficking regulator | 0.0232215 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0231519 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0230405 |
| HOMER1 | homer scaffolding protein 1 | 0.0229678 |
| PGK1 | phosphoglycerate kinase 1 | 0.0229574 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0228471 |
| LDHA | lactate dehydrogenase A | 0.0227934 |
| FOSL1 | FOS-like antigen 1 | 0.0227562 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0226865 |
| NRDC | nardilysin convertase | 0.0226778 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0225854 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0225561 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0225514 |
| MEF2A | myocyte enhancer factor 2A | 0.0224243 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0223895 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0223465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.215393 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.18279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162694 |
| FN1 | fibronectin 1 | -0.146095 |
| JUN | jun proto-oncogene | -0.121952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0867728 |
| SDC4 | syndecan 4 | -0.085906 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0857155 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0766208 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0729474 |
| CALU | calumenin | -0.0712463 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0704521 |
| SEC24D | SEC24 family member D | -0.0692986 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0680495 |
| MAP1B | microtubule-associated protein 1B | -0.0668501 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0630972 |
| COG5 | component of oligomeric golgi complex 5 | -0.0613206 |
| PTGES2 | prostaglandin E synthase 2 | -0.0609951 |
| HDLBP | high density lipoprotein binding protein | -0.059333 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0589324 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0582179 |
| INSIG1 | insulin induced gene 1 | -0.0561757 |
| CANX | calnexin | -0.055547 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0535278 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0530544 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0529936 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0510159 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0504846 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0497967 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0497201 |
| CDK13 | cyclin-dependent kinase 13 | -0.0496778 |
| COG6 | component of oligomeric golgi complex 6 | -0.0488483 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0482841 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0482401 |
| LOXL2 | lysyl oxidase-like 2 | -0.0477462 |
| CENPE | centromere protein E, 312kDa | -0.0470386 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0462635 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0455475 |
| CDH13 | cadherin 13 | -0.0455228 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0450158 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0442406 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0438329 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0421292 |
| TOP1 | topoisomerase (DNA) I | -0.0409871 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0408583 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0402201 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0401548 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0392171 |
| ITGAV | integrin, alpha V | -0.0390924 |
| TPM4 | tropomyosin 4 | -0.0387605 |
| RBM39 | RNA binding motif protein 39 | -0.0380638 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0379899 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0378084 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0377788 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376269 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0372216 |
| ATXN1 | ataxin 1 | -0.0364842 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0364094 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0363567 |
| HMGA2 | high mobility group AT-hook 2 | -0.0361109 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0360007 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0358476 |
| SUCO | SUN domain containing ossification factor | -0.0358285 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0356793 |
| LOX | lysyl oxidase | -0.0353632 |
| WASF2 | WAS protein family, member 2 | -0.0353608 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0346455 |
| KIF4A | kinesin family member 4A | -0.033679 |
| ASPH | aspartate beta-hydroxylase | -0.0336452 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0335383 |
| NOP58 | NOP58 ribonucleoprotein | -0.0334263 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0331989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331661 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0331615 |
| CCNL1 | cyclin L1 | -0.0330718 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0329632 |
| C1D | C1D nuclear receptor corepressor | -0.0325653 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0325093 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.03239 |
| SRP54 | signal recognition particle 54kDa | -0.0323347 |
| GLG1 | golgi glycoprotein 1 | -0.0322985 |
| ANO6 | anoctamin 6 | -0.0321441 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0317158 |
| SFTPA2 | surfactant protein A2 | -0.0315421 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0312284 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0308988 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0308259 |
| RPN2 | ribophorin II | -0.0307362 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.030641 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0306308 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0306076 |
| SMYD3 | SET and MYND domain containing 3 | -0.0304814 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0304799 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0300079 |
| SEC24A | SEC24 family member A | -0.0299389 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0296985 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0293124 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292817 |
| MSN | moesin | -0.0292588 |
| HM13 | histocompatibility (minor) 13 | -0.0292568 |
